Evaluation of Microleakage of Hesperidin incorporated dentin adhesive- an invitro study

Main Article Content

M. Shamly
Iffat Nasim


Hesperidin, Collagen-crosslinker, Total etch dentin adhesive, Micro-organisms, Quality of life


Background: Resin-dentin bonds are less durable than resin-enamel bonds, because of the heterogeneity of the structure and composition of dentin. The failure of resin-dentin bonding will result in microleakage, staining, recurrent caries, and postoperative sensitivity. Hesperidin as a natural collagen cross linker inhibits collagen degradation by MMP inhibition and also facilitates remineralization. Thus it can prevent microleakage and also further demineralization by improving dentin bond stability.
Materials And Methods: In total etch dentin adhesive, 2% hesperidin was added. Dye penetration testing with a stereomicroscope was used in class V cavities to analyse microleakage. The scoring method applied was comparable to that of Munro, Hilton, and Hermesch (2003). Independent sample t test was used for statistical analysis using statistical software version 23.
Results: For the test groups, microleakage values generally occurred at the junction of the restored dentin and enamel, whereas for the control groups, they mostly occurred at the junction of the restored dentin and axial wall. The difference was statistically significant in favour of the test group with less microleakage when compared to the control group, according to statistical analysis using the student t test (p value: 0.04).
Conclusion: Within the limitations, Hesperidin incorporated total etch dentin adhesive can be used effectively to reduce microleakage in total-etch adhesive restorations.
Clinical Significance: Microleakage at the adhesive interface can cause a number of issues, including secondary caries, post-operative sensitivity, and restorative failure. The durability and success rate of adhesive restorations can be increased by lowering microleakage with the use of hesperidin. For long-term therapeutic outcomes and patient satisfaction, this is especially crucial.

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