STUDY OF ANTIOXIDANT ACTIVITY OF PROPOLIS FROM DIFFERENT AREAS OF PUNJAB, PAKISTAN
Main Article Content
Keywords
Antioxidant, propolis, Natural products, Reactive oxygen species (ROS)
Abstract
This study investigates the antioxidant activity of propolis sourced from various regions of Punjab, Pakistan, specifically Jhang, Toba Tek Singh, and Sargodha. The findings indicate that propolis from these areas demonstrates significant antioxidant potential, suggesting its viability as a natural antioxidant for food supplements. However, further research is essential to isolate and quantify the key active compounds to better understand their specific biological activities. Expanding propolis collection to additional regions within Punjab will provide a more comprehensive evaluation of its antioxidant properties, enabling the identification of the most potent sources.
References
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3. Akyol, S., Ozturk, G., Ginis, Z., Armutcu, F., Yigitoglu, M. R., and Akyol, O. (2013). In vivo and in vitro antineoplastic actions of caffeic acid phenethyl ester (CAPE): therapeutic perspectives. Nutrition and Cancer, 65(4), 515-526.
4. ALaerjani, W. M. A., Khan, K. A., Al-Shehri, B. M., Ghramh, H. A., Hussain, A., Mohammed, M. E. A., and Al-Awadi, A. S. (2022). Chemical profiling, antioxidant, and antimicrobial activity of saudi propolis collected by arabian honey bee Apis mellifera jemenitica colonies. Antioxidants, 11(7), 1413-1431.
5. Ali, A. M., and Kunugi, H. (2021). Propolis, bee honey, and their components protect against coronavirus disease 2019 (Covid-19): A review of in silico, in vitro, and clinical studies. Molecules, 26(5), 1232-1241.
6. Al-Juhaimi, F. Y., Ozcan, M. M., Mohamed Ahmed, I. A., Alsawmahia, O. N., Ozcan, M. M., Ghafoor, K., and Babiker, E. E. (2022). Bioactive compounds, antioxidant activity, fatty acid composition, and antimicrobial activity of propolis from different locations in Turkey. Journal of Apicultural Research, 61(2), 246-254.
7. Almuhayawi, M. S. (2020). Propolis as a novel antibacterial agent. Saudi Journal of Biological Sciences, 27(11), 3079-3086.
8. Alvear, M., Santos, E., Cabezas, F., Pérez-SanMartín, A., Lespinasse, M., and Veloz, J. (2021). Geographic area of collection determines the chemical composition and antimicrobial potential of three extracts of chilean propolis. Plants, 10(8), 1543-1547.
9. Andrade, J. K. S., Denadai, M., de Oliveira, C. S., Nunes, M. L., and Narain, N. (2017). Evaluation of bioactive compounds potential and antioxidant activity of brown, green and red propolis from Brazilian northeast region. Food Research International, 101(4), 129-138.
10. Bankova, V., Bertelli, D., Borba, R., Conti, B. J., da Silva Cunha, I. B., Danert, C., Marcos N. E., Soraia I. F., María I.I., María I. N. M., Giulia P., Milena P., Karina B. S., Ana S., Alexandra C. H. F. S., Nicolas V. S., José M. S., Michael S. F., Marla S., Boryana T. M. V., Michael W., and Zampini, C. (2019). Standard methods for propolis research. Journal of Apicultural Research, 58(2), 1-49.
11. Bankova, V., Trusheva, B., and Popova, M. (2021). Propolis extraction methods: A review. Journal of Apicultural Research, 60(5), 734-743.
12. Banskota, A. H., Tezuka, Y., and Kadota, S. (2001). Recent progress in pharmacological research of propolis. Phytotherapy Research: PTR, 15(7), 561-571.
13. Bayram, E. N., Gerçek, Y. C., Bayram, S., and Toğar, B. (2020). Effects of processing methods and extraction solvents on the chemical content and bioactive properties of propolis. Journal of Food Measurement and Characterization, 14(4), 905-916.
14. Belmehdi, O., Bouyahya, A., Jekő, J., Cziáky, Z., Zengin, G., Sotkó, G., and Abrini, J. (2021). Chemical analysis, antibacterial, and antioxidant activities of flavonoid‐rich extracts from four Moroccan propolis. Journal of Food Processing and Preservation, 45(10), 15-19.
15. Calegari, M. A., Ayres, B. B., Tonial, L. M., de Alencar, S. M., and Oldoni, T. L. C. (2019). Fourier transform near infrared spectroscopy as a tool for predicting antioxidant activity of propolis. Journal of King Saud University-Science, 32(1), 784-790.
16. Christina, D., Hermansyah, H., Wijanarko, A., Rohmatin, E., Sahlan, M., Pratami, D. K., and Mun’im, A. (2018). Selection of propolis Tetragonula sp. extract solvent with flavonoids and polyphenols concentration and antioxidant activity parameters. In AIP Conference Proceedings, 1933(1), 11-20.
17. Cinegaglia, N. C., Bersano, P. R. O., Araújo, M. J. A. M., Búfalo, M. C., and Sforcin, J. M. (2013). Anticancer effects of geopropolis produced by stingless bees on canine osteosarcoma cells in vitro. Evidence-Based Complementary and Alternative Medicine, 20(13), 1444-1452.
18. Dezmirean, D. S., Paşca, C., Moise, A. R., and Bobiş, O. (2020). Plant sources responsible for the chemical composition and main bioactive properties of poplar-type propolis. Plants, 10(1), 22-27.
19. Dossena, S., and Marino, A. (2021). Cellular oxidative stress. Antioxidants, 10(3), 399.
20. Freires, I. A., de Alencar, S. M., and Rosalen, P. L. (2016). A pharmacological perspective on the use of Brazilian red propolis and its isolated compounds against human diseases. European Journal of Medicinal Chemistry, 110(3), 267-279.
21. Galeotti, F., Crimaldi, L., Maccari, F., Zaccaria, V., Fachini, A., and Volpi, N. (2017). Selective treatment to reduce contamination of propolis by polycyclic aromatic hydrocarbons (PAHs) still preserving its active polyphenol component and antioxidant activity. Natural product research, 31(17), 1971-1980.
22. Galeotti, F., Maccari, F., Fachini, A., and Volpi, N. (2018). Chemical composition and antioxidant activity of propolis prepared in different forms and in different solvents useful for finished products. Foods, 7(3), 41-45.
23. Garófalo, C.A. (2004). Diversidade e abundância de abelhas solitárias: viabilidade e utilização como polinizadores na agricultura. II Encuentro Colombiano Sobre Abejas Silvestres, 36(7), 111-117.
24. Ghisalberti, E. L. (1979). Propolis: A review. Bee World, 60(2), 59-84.
25. Greenleaf, S.S., and Kremen, C. (2006). Wild bees enhance honey bees’ pollination of hybrid sunflower. The Proceedings of the National Academy of Sciences, 103(4), 13890-13895.
26. Gregoris, E., and Stevanato, R. (2010). Correlations between polyphenolic composition and antioxidant activity of Venetian propolis. Food and Chemical Toxicology, 48(1), 76-82.
27. Guzelmeric, E., Yuksel, P. I., Yaman, B. K., Sipahi, H., Celik, C., Kırmızıbekmez, H., and Yesilada, E. (2021). Comparison of antioxidant and anti-inflammatory activity profiles of various chemically characterized Turkish propolis sub-types: Which propolis type is a promising source for pharmaceutical product development? Journal of Pharmaceutical and Biomedical Analysis, 203(5), 114-196.
28. Habryka, C., Socha, R., and Juszczak, L. (2020). The effect of enriching honey with propolis on the antioxidant activity, sensory characteristics, and quality parameters. Molecules, 25(5), 11-76.
29. Huang, S., Zhang, C. P., Wang, K., Li, G. Q., and Hu, F. L. (2014). Recent advances in the chemical composition of propolis. Molecules, 19(12), 19610-19632.
30. Jug, M., Končić, M. Z., and Kosalec, I. (2014). Modulation of antioxidant, chelating and antimicrobial activity of poplar chemo-type propolis by extraction procures. LWT-Food Science and Technology, 57(2), 530-537.
31. Kekecoglu, M., Eroğlu, N., Kambur, M., and Münir, U. Ç. A. K. (2020). The relationships between propolis collecting capability and morphometric features of some honey bee races and ecotypes in Anatolia. Journal of Agricultural Sciences, 26(1), 71-77.
32. Koh, C. L., Sam, C. K., Yin, W. F., Tan, L. Y., Krishnan, T., Chong, Y. M., and Chan, K. G. (2013). Plant-derived natural products as sources of anti-quorum sensing compounds. Sensors, 13(5), 6217-6228.
33. Kuropatnicki, A. K., Szliszka, E., and Krol, W. (2013). Historical aspects of propolis research in modern times. Evidence-Based Complementary and Alternative Medicine, 20(13), 1-11.
34. Machado, B. A. S., Silva, R. P. D., Barreto, G. D. A., Costa, S. S., Silva, D. F. D., Brandao, H. N., and Padilha, F. F. (2016). Chemical composition and biological activity of extracts obtained by supercritical extraction and ethanolic extraction of brown, green and red propolis derived from different geographic regions in Brazil. PloS one, 11(1), 45-54.
35. Majewska, M. B., and Majewski, J. (2016). Importance of bees in pollination of crops in the European union countries. Economic Science for Rural. Development. Proceedings of Conference, 42(20), 11-19.
36. Marco, S., Piccioni, M., Pagiotti, R., and Pietrella, D. (2017). Antibiofilm and antioxidant activity of propolis and bud poplar resins versus Pseudomonas aeruginosa. Evidence-Based Complementary and Alternative Medicine, 20(17), 31-39.
37. Michener, C. D. (2007). The bees of the world, (The Johns Hopkins University Press: Baltimore, USA).
38. Moreira, L., Dias, L. G., Pereira, J. A., and Estevinho, L. (2008). Antioxidant properties, total phenols and pollen analysis of propolis samples from Portugal. Food and Chemical Toxicology, 46(11), 3482-3485.
39. Mulyati, A. H., Sulaeman, A., Marliyati, S. A., Rafi, M., and Fikri, A. M. (2020). Phytochemical analysis and antioxidant activities of ethanol extract of stingless bee propolis from Indonesia. In AIP Conference Proceedings, 22(1), 09-14.
40. Nna, V. U., Bakar, A. B. A., Lazin, M. R. M. L. M., and Mohamed, M. (2018). Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats. Food and Chemical Toxicology, 120(6), 305-320.
41. Oliveira, I., Sousa, A., Ferreira, I. C., Bento, A., Estevinho, L., and Pereira, J. A. (2008). Total phenols, antioxidant potential and antimicrobial activity of walnut (Juglans regia L.) green husks. Food and Chemical Toxicology, 46(7), 2326-2331.
42. Oliveira, I., Sousa, A., Valentão, P., Andrade, P. B., Ferreira, I. C., Ferreres, F., and Pereira, J. A. (2007). Hazel (Corylus avellana L.) leaves as source of antimicrobial and antioxidative compounds. Food Chemistry, 105(3), 1018-1025.
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Jun 30, 2024
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Amina Ghaffar, Tahira Azam, Drakhshaan, Saleha Ashfaq, Rida Fatima, Ayesha Aslam, Tayyab Khurshid, Shumaila Yousaf, & Seemab Kousar. (2024). STUDY OF ANTIOXIDANT ACTIVITY OF PROPOLIS FROM DIFFERENT AREAS OF PUNJAB, PAKISTAN. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 2495-2521. https://doi.org/10.53555/jptcp.v31i6.6934
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Author Biographies
Amina Ghaffar
Department of Zoology, Government College University, Faisalabad Pakistan
Tahira Azam
Institute of Pharmaceutical Sciences, University of Veterinary & Animal Sciences, Lahore Pakistan
Drakhshaan
Institute of Pharmaceutical Sciences, University of Veterinary & Animal Sciences, Lahore Pakistan
Saleha Ashfaq
Department of Biology, The University of Haripur, KP, Pakistan
Rida Fatima
Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore.
Ayesha Aslam
Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore.
Tayyab Khurshid
Department of Pathology, University of Veterinary & Animals Sciences, Lahore Pakistan
Shumaila Yousaf
Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore.
Seemab Kousar
Department of Zoology, Government College University, Faisalabad Pakistan
How to Cite
Amina Ghaffar, Tahira Azam, Drakhshaan, Saleha Ashfaq, Rida Fatima, Ayesha Aslam, Tayyab Khurshid, Shumaila Yousaf, & Seemab Kousar. (2024). STUDY OF ANTIOXIDANT ACTIVITY OF PROPOLIS FROM DIFFERENT AREAS OF PUNJAB, PAKISTAN. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 2495-2521. https://doi.org/10.53555/jptcp.v31i6.6934