EXPLORING ADVANCEMENTS IN VETERINARY MEDICINE: A COMPREHENSIVE REVIEW OF CURRENT TRENDS AND INNOVATIONS
Main Article Content
Keywords
Veterinary Medicine, Innovation, Technology, One Health, Therapeutics
Abstract
This review covers almost every aspect of veterinary medicine, including preventative medicine, surgical procedures, diagnostic procedures, therapeutic methods, and technological breakthroughs on the subject. Wearable devices, digital health platforms, and telemedicine are examples of technology innovations that have had a significant influence on the delivery of veterinary care. These advancements have improved the availability of online consultations, point-of-care patient monitoring, and client communication. One Health programs and interdisciplinary cooperation are becoming increasingly important in the process of tackling emerging health challenges, as evidenced by global trends that have an impact on veterinary education, research, and practice. In addition, as a result of recent advancements in therapeutic intervention, surgical procedures, and the incorporation of technology in veterinary medicine, the transformative potential of immunotherapy, gene therapy, minimally invasive surgery, and drug delivery systems based on nanotechnology has been established. By providing a comprehensive summary of recent developments and discoveries, the purpose of this study is to educate veterinarians, researchers, educators, and lawmakers on the most recent innovations that will influence veterinary healthcare in the future.
References
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29. Nguyen, F., Fergus, M., & Hodge, A. (2020). Telemedicine in Veterinary Practice. In G. D. DiGiacomo & C. E. Rousseau (Eds.), Veterinary Telemedicine: A Practical Guide to Telemedicine Protocols in Veterinary Practice (pp. 39-47). Wiley.
30. Thomason, J. D., Creevy, K. E., & Goggs, R. (2021). Artificial intelligence and machine learning in veterinary medicine: An overview. The Veterinary Journal, 272, 105648.
31. Zinsstag, J., Schelling, E., Waltner-Toews, D., Whittaker, M., Tanner, M., & Waltner-Toews, D. (2021). One Health: The Theory and Practice of Integrated Health Approaches. CABI.
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33. Freeman, L. M., Lofgren, J. L., Nguyen, P., & Jewell, D. E. (2020). Postgraduate Continuing Education for Veterinarians: An Industry in Need of Resuscitation. Veterinary Clinics of North America: Small Animal Practice, 50(6), 1083-1094.
34. Weaver, D. S. (2017). Veterinary Medical Education in the Age of One Health. Journal of Veterinary Medical Education, 44(1), 11-16.
35. Ko S, Abatan MO. Biotechnology a key tool to breakthrough in medical and veterinary research. Biotechnology and Molecular Biology Review. 2008;3(4):088-094.
36. Patil A, Chan C, Dyavaiah M, Rooney JP, Dedon P. Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications. RNA Biology. 2012;9(7):990-1001.
37. Cutrera J, King G, Jones P, Kicenuik K, Gumpel E, Xia X, Li S. Safe and effective treatment of spontaneous neoplasms with interleukin 12 electro‐chemo‐gene therapy. Journal of Cellular and Molecular Medicine. 2015;19(3):664-675.
38. Calvet CY, Mir LM. The promising alliance of anti-cancer electrochemotherapy with immunotherapy. Cancer and Metastasis Reviews. 2016;1-13.
39. Beltran WA, Cideciyan AV, Lewin AS, Iwabe S, Khanna H, Sumaroka A, Swider M. Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human Xlinked retinitis pigmentosa. Proceedings of the National Academy of Sciences. 2012;109(6):2132-2137.
40. Callejas D, Mann CJ, Ayuso E, Lage R, Grifoll I, Roca C, Ferre T. Treatment of diabetes and long-term survival following insulin and glucokinase gene therapy. Diabetes. 2013;DB_121113.
41. Callan MB, Haskins ME, Wang P, Zhou S, High KA, Arruda VR. Successful phenotype improvement following gene therapy for severe hemophilia a in privately owned dogs. PloS one. 2016;11(3):e0151800.
42. Liew PS, Hair-Bejo M. Farming of plant-based veterinary vaccines and their applications for disease prevention in animals. Advances in Virology. 2015;12. Article ID: 936940
43. Borroto CG. Biotechnology and its application to veterinary science. Conf. Office International des Epizooties (OIE), World organization for Animal health. 2008;231-240.
44. Salih B, Tripathi V, Trifonov EN. Visible periodicity of strong nucleosome DNA sequences. Journal of Biomolecular Structure and Dynamics. 2015;33(1):1-9.
45. Maharana BR, Tewari AK, Saravanan BC, Sudhakar NR. Important hemoprotozoan diseases of livestock: Challenges in current diagnostics and therapeutics: An update. Veterinary World. 2016;9(5):487.
46. Meyfour A, Tavirani MR, Sadeghi MR. Common proteomic technologies, applications, and their limitations. Journal of Paramedical Sciences. 2013;4.
47. Ceciliani F, Eckersall D, Burchmore R, Lecchi C. Proteomics in veterinary medicine applications and trends in disease pathogenesis and diagnostics. Veterinary Pathology Online. 2014;51(2):351-362.
48. Schrödl W, Büchler R, Wendler S, Reinhold P, Muckova P, Reindl J, Rhode H. Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine. Proteomics-Clinical Applications; 2016.
49. Schmitt B, Henderson L. Diagnostic tools for animal diseases. Revue Scientifique et TechniqueOffice International des Épizooties. 2005;24(1):243.
50. Rest J.S. & Mindell D.P. (2003). – SARS associated coronavirus has a recombinant polymerase and coronaviruses have a history of host-shifting. Infect. Genet. Evol., 3 (3), 219- 225.
51. Frenkal M.A. & Borkan J.M. (2003). – An approach for integrating complementary-alternative medicine into primary health care. Fam. Prac., 20 (3), 324-332.
52. Hermansen J.E. (2003). – Organic livestock production systems and appropriate development in relation to public expectations. Livest. Prod. Sci., 80, 3-15.
53. Banville A. (1994). – Consumer pressures against compounding. JAVMA, 205 (2), 286-287.
54. Parry J.R. & Vincent A. (1998). – Can we tame wild medicine? New Scient., 1, 26-29.
2. Lacetera, N. (2019). Impact of climate change on animal health and welfare. Animal Frontiers, 9(1), 26-31.
3. Forastiere, F. 2010. Climate change and health: a challenge for epidemiology and public health. Int. J. Public Health 55:83–84. doi:10.1007/ s00038-009-0096-9.
4. Ballester, J., J.-M. Robine, F.R. Herrmann, and X. Rodó. 2011. Long-term projections and acclimatization scenarios of temperature-related mortality in Europe. Nat. Commun. 2:358. doi:10.1038/ncomms1360.
5. Rose, H., T. Wang, J. van Dijk, and E.R. Morgan. 2015. GLOWORM-FL: a simulation model of the effects of climate and climate change on the free-living stages of gastro-intestinal nematode parasites of ruminants. Ecol. Mod. 297:232–245. doi:10.1016/j.ecolmodel.2014.11.033
6. Buller H, Blokhuis H, Jensen P, Keeling L. Towards farm animal welfare and sustainability. Animals. (2018) 8. doi: 10.3390/ani806 0081
7. World Organisation for Animal Health (OIE). Internet Website Accessed in December. (2018). Available online at: http://www.oie.int/index.php?id=169& L=0&htmfile=chapitre_aw_introduction.htm (accessed September 24, 2019).
8. Pinillos RC, Appleby MC, Manteca X, Scott-Park F, Smith C, Velarde A. One welfare—a platform for improving human and animal welfare. Vet Record. (2016) 179:412–3. doi: 10.1136/vr.i5470
9. Lerner H, Berg C. The concept of health in one health and some practical implications for research and education: what is one health? J Infect Ecol Epidemiol. (2015) 5. doi: 10.3402/iee.v5.25300
10. Le Gall FG, Plante CA, Berte FCJ, Bouley T, Seifman RM, Karesh WB, et al. Operational framework for strengthening human, animal and environmental public health systems at their interface. World Bank Group (2018) 138.
11. Gardiner, A. (2021). History of veterinary medicine. Handbook of Historical Animal Studies; Roscher, M., Krebber, A., Mizelle, B., Eds, 493-508.
12. Hunter, P. (2016). Veterinary medicine: a guide to historical sources. Routledge.
13. Wynn, S. G., & Fougère, B. J. (2007). The roots of veterinary botanical medicine. Veterinary. Herbal. Med, 33-49.
14. Mitsuda, T. (2017). Entangled histories: German veterinary medicine, c. 1770–1900. Medical History, 61(1), 25-47.
15. Zinsstag, J., Schelling, E., Waltner-Toews, D., Whittaker, M., Tanner, M., & Waltner-Toews, D. (2021). One Health: The Theory and Practice of Integrated Health Approaches. CABI.
16. Nguyen, F., Fergus, M., & Hodge, A. (2020). Telemedicine in Veterinary Practice. In G. D. DiGiacomo & C. E. Rousseau (Eds.), Veterinary Telemedicine: A Practical Guide to Telemedicine Protocols in Veterinary Practice (pp. 39-47). Wiley.
17. Strasser, R., Flock, D., Giguère, S., & Stull, J. (2020). Teaching Animal Welfare and Ethics in Veterinary Education. In A. M. Hewson & J. P. H. Rivers (Eds.), Veterinary Clinical Ethics: A Practical Guide (pp. 295-303). Springer.
18. Santos, E. A., Kaelber, J. T., Murthy, K., & Wagner, J. E. (2020). Gene Therapy for Genetic Diseases in Companion Animals: From Promise to Reality. Frontiers in Genetics, 11, 509.
19. Grosenbaugh, D. A., Leard, A. T., Bergman, P. J., Klein, M. K., Meleo, K., Susaneck, S., ... & Milner, R. (2011). Safety and efficacy of a xenogeneic DNA vaccine encoding for human tyrosinase as adjunctive treatment for oral malignant melanoma in dogs following surgical excision of the primary tumor. American Journal of Veterinary Research, 72(12), 1631-1638.
20. Vilar, J. M., Batista, M., Morales, M., Santana, A., Cuervo, B., Rubio, M., ... & Cugat, R. (2014). Assessment of the effect of intra-articular injection of autologous adipose-derived mesenchymal stem cells in osteoarthritic dogs using a double blinded force platform analysis. BMC Veterinary Research, 10(1), 1-7.
21. Suk, J. S., Xu, Q., Kim, N., Hanes, J., & Ensign, L. M. (2016). PEGylation as a strategy for improving nanoparticle-based drug and gene delivery. Advanced Drug Delivery Reviews, 99, 28-51.
22. London, C. A., Bernabe, L. F., Barnard, S., Kisseberth, W. C., Borgatti, A., Henson, M., ... & Henry, C. J. (2019). Preclinical Evaluation of the Novel, Orally Bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Spontaneous Canine Cancer: Results of a Phase I Study. PloS One, 14(3), e0209464.
23. Steffey, M. A., Garcia-Nolen, T., & Park, S. A. (2003). Laparoscopic techniques in small animals. The Veterinary Clinics of North America. Small Animal Practice, 33(5), 1129-1150.
24. Sacher, A., & Mayhew, P. D. (2018). Arthroscopy in Small Animals: Principles and Techniques for the Veterinary Orthopedic Surgeon. Veterinary Clinics of North America: Small Animal Practice, 48(1), 27-55.
25. Kalb, S., Mahler, J., & Koenig, A. (2017). Robot-assisted laparoscopy in small animal surgery. The Veterinary Clinics of North America. Small Animal Practice, 47(2), 473-493.
26. Chanoit, G., McKee, W. M., & Laporte, J. M. (2005). The use of surgical robots in orthopaedic surgery. The Veterinary Journal, 170(1), 28-38.
27. Steagall, P. V., Monteiro, B. P., & Ruel, H. L. (2013). A systematic review of the analgesic efficacy of cannabinoid medications in the management of acute postoperative pain. Veterinary Anaesthesia and Analgesia, 40(3), 251-260.
28. Freeman, L. J., Rahmani, E. Y., & Al-Nadaf, S. (2006). Use of a board-certified surgeon vs a non-board-certified surgeon: outcome and cost analysis. Journal of the American Veterinary Medical Association, 229(12), 2114-2118.
29. Nguyen, F., Fergus, M., & Hodge, A. (2020). Telemedicine in Veterinary Practice. In G. D. DiGiacomo & C. E. Rousseau (Eds.), Veterinary Telemedicine: A Practical Guide to Telemedicine Protocols in Veterinary Practice (pp. 39-47). Wiley.
30. Thomason, J. D., Creevy, K. E., & Goggs, R. (2021). Artificial intelligence and machine learning in veterinary medicine: An overview. The Veterinary Journal, 272, 105648.
31. Zinsstag, J., Schelling, E., Waltner-Toews, D., Whittaker, M., Tanner, M., & Waltner-Toews, D. (2021). One Health: The Theory and Practice of Integrated Health Approaches. CABI.
32. Rabinowitz, P. M., Kock, R., Kachani, M., Kunkel, R., Thomas, J., Gilbert, J., ... & Taylor, L. (2018). Toward proof of concept of a one health approach to disease prediction and control. Emerging Infectious Diseases, 24(1), e180047.
33. Freeman, L. M., Lofgren, J. L., Nguyen, P., & Jewell, D. E. (2020). Postgraduate Continuing Education for Veterinarians: An Industry in Need of Resuscitation. Veterinary Clinics of North America: Small Animal Practice, 50(6), 1083-1094.
34. Weaver, D. S. (2017). Veterinary Medical Education in the Age of One Health. Journal of Veterinary Medical Education, 44(1), 11-16.
35. Ko S, Abatan MO. Biotechnology a key tool to breakthrough in medical and veterinary research. Biotechnology and Molecular Biology Review. 2008;3(4):088-094.
36. Patil A, Chan C, Dyavaiah M, Rooney JP, Dedon P. Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications. RNA Biology. 2012;9(7):990-1001.
37. Cutrera J, King G, Jones P, Kicenuik K, Gumpel E, Xia X, Li S. Safe and effective treatment of spontaneous neoplasms with interleukin 12 electro‐chemo‐gene therapy. Journal of Cellular and Molecular Medicine. 2015;19(3):664-675.
38. Calvet CY, Mir LM. The promising alliance of anti-cancer electrochemotherapy with immunotherapy. Cancer and Metastasis Reviews. 2016;1-13.
39. Beltran WA, Cideciyan AV, Lewin AS, Iwabe S, Khanna H, Sumaroka A, Swider M. Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human Xlinked retinitis pigmentosa. Proceedings of the National Academy of Sciences. 2012;109(6):2132-2137.
40. Callejas D, Mann CJ, Ayuso E, Lage R, Grifoll I, Roca C, Ferre T. Treatment of diabetes and long-term survival following insulin and glucokinase gene therapy. Diabetes. 2013;DB_121113.
41. Callan MB, Haskins ME, Wang P, Zhou S, High KA, Arruda VR. Successful phenotype improvement following gene therapy for severe hemophilia a in privately owned dogs. PloS one. 2016;11(3):e0151800.
42. Liew PS, Hair-Bejo M. Farming of plant-based veterinary vaccines and their applications for disease prevention in animals. Advances in Virology. 2015;12. Article ID: 936940
43. Borroto CG. Biotechnology and its application to veterinary science. Conf. Office International des Epizooties (OIE), World organization for Animal health. 2008;231-240.
44. Salih B, Tripathi V, Trifonov EN. Visible periodicity of strong nucleosome DNA sequences. Journal of Biomolecular Structure and Dynamics. 2015;33(1):1-9.
45. Maharana BR, Tewari AK, Saravanan BC, Sudhakar NR. Important hemoprotozoan diseases of livestock: Challenges in current diagnostics and therapeutics: An update. Veterinary World. 2016;9(5):487.
46. Meyfour A, Tavirani MR, Sadeghi MR. Common proteomic technologies, applications, and their limitations. Journal of Paramedical Sciences. 2013;4.
47. Ceciliani F, Eckersall D, Burchmore R, Lecchi C. Proteomics in veterinary medicine applications and trends in disease pathogenesis and diagnostics. Veterinary Pathology Online. 2014;51(2):351-362.
48. Schrödl W, Büchler R, Wendler S, Reinhold P, Muckova P, Reindl J, Rhode H. Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine. Proteomics-Clinical Applications; 2016.
49. Schmitt B, Henderson L. Diagnostic tools for animal diseases. Revue Scientifique et TechniqueOffice International des Épizooties. 2005;24(1):243.
50. Rest J.S. & Mindell D.P. (2003). – SARS associated coronavirus has a recombinant polymerase and coronaviruses have a history of host-shifting. Infect. Genet. Evol., 3 (3), 219- 225.
51. Frenkal M.A. & Borkan J.M. (2003). – An approach for integrating complementary-alternative medicine into primary health care. Fam. Prac., 20 (3), 324-332.
52. Hermansen J.E. (2003). – Organic livestock production systems and appropriate development in relation to public expectations. Livest. Prod. Sci., 80, 3-15.
53. Banville A. (1994). – Consumer pressures against compounding. JAVMA, 205 (2), 286-287.
54. Parry J.R. & Vincent A. (1998). – Can we tame wild medicine? New Scient., 1, 26-29.
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May 25, 2024
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Areesha Arkan, Zia Ullah, Shahzad Ahmad, Naveed Hussain, Iqra Mehroz, Ali Qaisar, Hafsa Sarfraz, & Abdul Aziz. (2024). EXPLORING ADVANCEMENTS IN VETERINARY MEDICINE: A COMPREHENSIVE REVIEW OF CURRENT TRENDS AND INNOVATIONS. Journal of Population Therapeutics and Clinical Pharmacology, 31(5), 1367–1377. https://doi.org/10.53555/jptcp.v31i5.6347
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Author Biographies
Areesha Arkan
Department of Veterinary Surgery, University of Veterinary and Animal Sciences Lahore, 54000, Pakistan.
Zia Ullah
Department of Veterinary Surgery, University of Veterinary and Animal Sciences Lahore, 54000, Pakistan
Shahzad Ahmad
Department of Veterinary Surgery, University of Veterinary and Animal Sciences Lahore, 54000, Pakistan.
Naveed Hussain
Department of Veterinary Surgery, University of Veterinary and Animal Sciences Lahore, 54000, Pakistan.
Iqra Mehroz
Department of Veterinary Surgery, University of Veterinary and Animal Sciences Lahore, 54000, Pakistan.
Ali Qaisar
Department of Veterinary Surgery, University of Veterinary and Animal Sciences Lahore, 54000, Pakistan
Hafsa Sarfraz
University of Veterinary and Animal Science Lahore, Department of Pathology.
Abdul Aziz
Department of Veterinary Clinical Sciences, University of Poonch Rawalakot, Pakistan