Main Article Content

Zarish Sultan
Hira Iftikhar
Iqra Khalid
Huda Ismail
Tabish Ali Virk
Marzough Aziz Albalawi
Fatema Suliman Alatawi
Mohsen Suliman Alatawi
Amnah A. Alharbi
Sanaa Almowallad
Mody Albalawi
Nizwa itrat


Systematic skeleton disease, chronic metabolic bone disease, Osteoporosis, Barley gras


Osteoporosis is systematic skeleton disease that is defined by low bone mass and changes in structure of bone tissue, which leads to high risks of weak bones and fractures. According to International Osteoporosis Foundation 1 in 3 women and 1 in 5 men over the age 50 years are suffering from osteoporosis. Barley grass powder is the best functional food for supplying nutrients and removing toxins from human cells, its functional components have also provided significant health benefits because it contains many nutrients such as essential amino acids, fiber, vitamins and both micro and macro minerals. The present study was conducted to evaluate the therapeutic effect of barley grass powder in treatment and prevention of osteoporosis in females. For this purpose, characterization (proximate analysis) of barley grass powder was conducted as an initial part of study. Human efficacy was carried out on 45 osteoporotic females in 3 groups, giving them barley grass powder for 60 days with different dosages, G0 was treated as control group, G1 was group was given 5g of barley grass powder and G2 was given 10 g of barley grass powder per day before any meal. Their BMD was checked before and after the completion of study. The data obtained was subjected to statistical analysis for the evaluation of results. The results showed that barley grass powder contained moisture 16 %, ash 18.95 %, fat3.8 %, protein 8.75 %, and fiber 8.16 %, NFE 44. 34 % and dry matter 84 %. The results of BMD values of treatment groups (G1 and G2) were significantly (p≤ (0.05) increased as compared to the BMD values of control group. It showed that barley grass powder can be used for the treatment of osteoporosis.


Abstract 391 | pdf Downloads 196


1. Comparison of hydrability, antioxidants, microstructure, and sensory quality of barley grass powder using ultra‐micro‐crushing combined with hot air and freeze drying. Food Science & Nutrition. 2021 Apr; 9(4):1870-80.
2. Zeng Y, Pu X, Yang J, Du J, Yang X, Li X, Li L, Zhou Y, Yang T. Preventive and therapeutic role of functional ingredients of barley grass for chronic diseases in human beings. Oxidative medicine and cellular longevity. 2018 Apr 4;2018
3. Chang KH, Lai CH, Chen SC, Tang IN, Hsiao WT, Liou TH, Lee CM. Femoral neck bone mineral density in ambulatory men with poliomyelitis. Osteoporosis international. 2011 Jan;22(1):195-200.
4. .Selem MS, Elgendy SA, Afify WA, Sweid EM, Menem A. Bone Densitometry in Children with Idiopathic Nephrotic Syndrome. Benha Journal of Applied Sciences. 2019 Zhou W, Cao X, Islam MN, Zheng H, Li J, Liu F, Cao Y, Dai Y. Mar 1;4(1):127-34.
5. Akkawi I, Zmerly H. Osteoporosis: current concepts. Joints. 2018 Jun; 6(02):122-7.
6. Marcucci G, Brandi ML. Rare causes of osteoporosis. Clinical cases in mineral and bone metabolism. 2015 May;12(2):151.
7. AACC. Approved Methods of Analysis, 10th ed.; American Association of Cereal Chemists. Inc: St. Paul, MN, 2000.
8. AOAC. Official Methods of Analysis, 16th ed.; The Association of Official Analytical Chemicals. Inc.: Arlington, USA, 1990.
9. Taga, M.-S.; Miller, -E.-E.; Pratt, D.-E. China Seeds as Source of Natural Lipid Antioxidation. J. Am. Oil Chemists’ Soc. 1984, 61, 928–931.
10. Ordon-Ez, -A.-A.-L.; Gomez, J.-D.; Vattuone, M.-A.; Isla, M. I. Antioxidant Activities of Sechium Edule (Jacq.) Swart Extracts. Food Chem. 2006, 97, 452–458. DOI: 10.1016/j.foodchem.2005.05.024.
11. Cho, C.W., Song, Y.R., Lim, W.C., Hwang, Y.H., Rhee, Y.K., Choi, J.W., Lee, K.T. and Hong, H.D., 2020. Acute oral toxicity and genotoxicity of polysaccharide fraction from young barley leaves (Hordeum vulgare L.). Foods, 9(6), p.809.
12. Liu, Peterson, K.L. and Raboy, V., 2007. Comparison of the phosphorus and mineral concentrations in bran and abraded kernel fractions of a normal barley (Hordeum vulgare) cultivar versus four low phytic acid isolines. Journal of Agricultural and Food Chemistry, 55(11), pp.4453-4460.
13. Gelagay, B., 2011. Study on the levels of some essential and non-essential metals in four different varieties of barley (Hordeum vulgare l.) Grown in dale and aleta wondo woredas, in Sidamo zone, Ethiopia (doctoral dissertation).
14. Elbakry, K.A.E.A.E., Alazabi, N.I., Omer, N.M., Bahnasawy, M.H. and Ahmed-Farid, O.A.H., 2019. Physiological and behavioral study on depressed rats model treated with Hordeum vulgare extract referenced to SSRI class. Biomedical Research and Therapy, 6(9), pp.3379-3390.
15. Wahman, L.F., Abd Rabo, M.M., Elgoly, A.H.M. and Yousef, M.H., 2020. Potential Role of Plants Hordeum vulgare L. and Panax ginseng L. in Resolving the Fertility Disorders and Stress-Induced Oxidative Stress Arises from Hypothyroidism in Adult Female Rats. In Plant Stress Physiology. IntechOpen.
16. Elbakry, K.A.E.A.E., Alazabi, N.I., Omer, N.M., Bahnasawy, M.H. and Ahmed-Farid, O.A.H., 2019. Physiological and behavioral study on depressed rats model treated with Hordeum vulgare extract referenced to SSRI class. Biomedical Research and Therapy, 6(9), pp.3379-3390.
17. Tao, J.H., Gong, X.Y., Cao, Y.L., Zhang, Q.Y., Jing, S.S., Wang, H. and Chen, Y.G., 2021. Mechanism of barley malt-dependent DRD2 to treat hyperprolactinemia based on UPLC-Q-TOF/MS and network pharmacology. European Journal of Integrative Medicine, 43, p.101322.

Most read articles by the same author(s)