AN OBSERVATIONAL STUDY OF HEPATITIS C INFECTION IN PREGNANT WOMEN BY USING SEROLOGICAL DIAGNOSTIC METHOD.
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Keywords
Hepatitis C virus, Antenatal care, Enzyme linked immunosorbent assay, Pregnancy.
Abstract
Hepatitis C virus infection remains a significant public health problem worldwide. Over 71 million people’s deaths result from complications of untreated chronic HCV infection. A major barrier to HCV elimination still results from the fact that a substantial proportion of patients with chronic HCV infection are unaware of their infection, with large variations across different regions, countries and risk populations. Pregnant women constitute a vulnerable population due to the risk of vertical transmission. This study aims to determine the seroprevalence of HCV infection among pregnant women attending the Antenatal care in Index medical college, department of microbiology.
Objective: To Assess the demographic and risk factors associated with HCV positivity and highlight the importance of routine HCV screening in antenatal care. Seropositive cases with gestational diabetes and risk factors associated with acquisition of HCV infection & to estimate the HCV infection by detecting antibody and/ or antigen by ELISA/Rapid test.
Method: An observational study design was used. Pregnant women attending the ANC clinic during the study period were screened for HCV antibodies using Standard ELISA technique. Demographic and clinical data were collected using a structured questionnaire in our ANC department clinic of Index medical college & hospital Indore.
Result: Out of the 109 pregnant women attending ANC clinic in institute a total of 3 were found to be positive for anti-HCV antibody & confirm by ELISA test where 2.7% seropositive rate were found to be in this study.
Conclusion: In our study were concluded that insignificant seroprevalence of HCV in pregnant women those who attend the ANC department of index medical college. Early detection enables counseling and monitoring. Direct-acting antiviral (DAA) therapy can be planned postpartum. Infants born to HCV-positive mothers can be followed up for timely diagnosis.
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Dr Kailash Jatav
Associate Professor, Department of Microbiology, Index Medical College, Hospital & Research Centre, Indore, M.P. Email: kailasha099@gmail.com
Chesta Rani
Ph.D. Scholar, Department of Microbiology Index Medical College, Hospital & Research Centre, Indore, M.P. India, Email: chesta09r@gmail.com
Ravi Kumar
Assistant Professor, Department of Forensic Science, Teerthanker Mahaveer University, Moradabad, U.P. Email: Ravi.Paramedical@tmu.ac.in
