HEALTH AND TREATMENT OUTCOMES OF TUBERCULOSIS PATIENTS WITH DIABETES DURING AND AFTER TREATMENT

Main Article Content

Saima Rafique
Nasira Sohail
Mahesh Kumar
Sarfaraz Ahmed
Ravi Kumar
Muhammad Sohail Baig

Keywords

tuberculosis, diabetes mellitus, treatment outcomes

Abstract

Background: World's disease patterns have shifted, with communicable diseases (CDs) declining and noncommunicable diseases (NCDs) increasing. This change has resulted in a struggle for policy attention and resources between supporters of CDs such as tuberculosis (TB) and NCDs such as cardiovascular disease and diabetic mellitus (DM). Currently, there are around 9.6 million new tuberculosis cases per year worldwide, with 1 million of these individuals also having diabetes. The bidirectional link between TB and diabetes suggests that diabetes increases the likelihood of developing TB, whereas TB can cause impaired glucose tolerance (IGT) and new-onset diabetes.


Objective: To monitor the health and treatment outcomes of tuberculosis patients with diabetes during and after treatment


Study design: A longitudinal study


Place and Duration: This study was conducted in Bhitai Dental and Medical College Mirpurkhas from April 2023 to April 2024


Methodology: The participants were all tuberculosis patients who were newly registered with DM cases. A random blood sugar test was used to screen all TB patients for the detection of diabetes mellitus. A laboratory technician collected the samples, which were then analyzed in the lab. All TB patients were checked for diabetes using a random blood sugar test, with samples collected and analyzed by a lab technician.


Results: There were a total of 70 cases that were enrolled in this research. The male to female ratio was 3:1. Majority of the cases were from the age group 51 years to 60 years. Majority of the cases were from urban slum areas.


Conclusion: The integration of tuberculosis and diabetes care improves treatment outcomes and quality of life, which is critical for treating TB and DM effectively.

Abstract 35 | PDF Downloads 19

References

1. Solanki HM, Ranpariya PN, Chudasama RK. Health Status and Treatment Outcome of Tuberculosis with Diabetes Mellitus Cases, Rajkot City, Gujarat–A Longitudinal Study. Indian Journal of Community Medicine. 2023 Jan 1;48(1):75-81.
2. Mishra GP, Munje RP, Dawkore MB. Diabetes and Tuberculosis–Tackling Double Trouble. Indian J Basic Appl Med Res. 2018;8:256-60.
3. Swain A, Rao AP, Sanju SC, Kumar S. Factors affecting diabetes management among tuberculosis-diabetes comorbid patients in Udupi District. Indian Journal of Community Medicine. 2021 Oct 1;46(4):731-4.
4. Sembiah S, Nagar V, Gour D, Pal DK, Mitra A, Burman J. Diabetes in tuberculosis patients: an emerging public health concern and the determinants and impact on treatment outcome. Journal of Family and Community Medicine. 2020 May 1;27(2):91-6.
5. Ranganath TS, Shivaraj BM. A study on tuberculosis treatment outcome in known diabetic patients treated under Revised National Tuberculosis Control Program in Bengaluru. International Journal of Medicine & Public Health. 2015 Jan 1;5(1).
6. Ghanta J, Panja B, Goswami D, Karmakar M, Kundu S, Sen S. The effect of diabetes mellitus on the treatment outcome of tuberculosis. Indian Journal of Public Health Research & Development. 2023 Mar 15;14(2):107-14.
7. Mukhtar F, Butt ZA. Cohort profile: the diabetes-tuberculosis treatment outcome (DITTO) study in Pakistan. BMJ open. 2016 Dec 1;6(12):e012970.
8. Pande T, Huddart S, Xavier W, Kulavalli S, Chen T, Pai M, Saravu K. Prevalence of diabetes mellitus amongst hospitalized tuberculosis patients at an Indian tertiary care center: a descriptive analysis. PloS one. 2018 Jul 18;13(7):e0200838.
9. Jali MV, Mahishale VK, Hiremath MB, Satyanarayana S, Kumar AM, Nagaraja SB, Isaakidis P. Diabetes mellitus and smoking among tuberculosis patients in a tertiary care centre in Karnataka, India. Public health action. 2013 Nov 4;3(1):51-3.
10. Raghuraman S, Vasudevan KP, Govindarajan S, Chinnakali P, Panigrahi KC. Prevalence of diabetes mellitus among tuberculosis patients in urban Puducherry. North American journal of medical sciences. 2014 Jan;6(1):30.
11. Tahir Z, Akhtar AM, Yaqub T, Mushtaq MH, Javed H. Diabetes mellitus among tuberculosis patients: a cross sectional study from Pakistan. African health sciences. 2016;16(3):671-6.
12. Jacob S, George LS, Joy A, Mathew MM, Vijayakumar K, Kumar A, Kunoor A. Prevalence of diabetes mellitus and HIV/AIDS among tuberculosis patients in Kerala. Journal of family medicine and primary care. 2020 Dec 31;9(12):6209-12.
13. Mahato RK, Laohasiriwong W, Koju R. The role of Diabetes mellitus comorbidity on Tuberculosis treatment outcomes in Nepal: A prospective cohort study. South Eastern European Journal of Public Health. 2023 Jan 24.
14. KV N, Duraisamy K, Balakrishnan S, Sagili KD, Satyanarayana S, MV AK, Enarson DA. Outcome of tuberculosis treatment in patients with diabetes mellitus treated in the revised national tuberculosis control programme in Malappuram District, Kerala, India. PloS one. 2013 Oct 14;8(10):e76275.
15. Nagar V, Gour D, Pal DK, Singh AR, Joshi A, Dave L. A study on prevalence of diabetes and associated risk factors among diagnosed tuberculosis patients registered under Revised National Tuberculosis Control Programme in Bhopal District. Journal of Family Medicine and Primary Care. 2018 Jan 1;7(1):130-6.
16. Dey D, Patra BC, Ghosh D. High Diabetes prevalence among males Tuberculosis patients in East Medinipur District of West Bengal, India. Int. J. Adv. Res. 2015;3(4):940-4.
17. Sharma D, Goel NK, Sharma MK, Walia DK, Thakare MM, Khaneja R. Prevalence of diabetes mellitus and its predictors among tuberculosis patients currently on treatment. Indian journal of community medicine. 2018 Oct 1;43(4):302-6.
18. Balakrishnan S, Vijayan S, Nair S, Subramoniapillai J, Mrithyunjayan S, Wilson N, Satyanarayana S, Dewan PK, Kumar AM, Karthickeyan D, Willis M. High diabetes prevalence among tuberculosis cases in Kerala, India.
19. Joshi R, Behera D, Di Tanna GL, Ameer MA, Yakubu K, Praveen D. Integrated Management of Diabetes and Tuberculosis in rural India–results from a pilot Study. Frontiers in Public Health. 2022 May 10;10:766847.
20. Dutt N, Gupta A. A study on diabetes mellitus among cases of pulmonary tuberculosis in a tertiary care Hospital, Ahmedabad. National Journal of Medical Research. 2014 Dec 31;4(04):349-53.