STATUS OF HEMOGLOBIN LEVEL IN PENUMONIA PATIENT UNDER 5 YEARS

Main Article Content

Muhammad Owais
Hameed Ullah
Haleema Begum
Muhammad Ramzan Waris
Aisha Durrani
Madiha Gul

Keywords

Haemoglobin, pneumonia, anaemia, paediatric.

Abstract

Background:  pneumonia is rated as one of the main causes of morbidity and mortality, chiefly in the developing world. Patients in these groups have haemoglobin levels that can be influenced by inflammation, nutritional deficiency or other disease, thus their recovery. The learning objectives of this research include determining haemoglobin status among pneumonic children.


Objectives: To measure plasma haemoglobin concentration in children with pneumonia and less than five years, evaluate the relationship between anaemia and disease severity and to describe the influence of the severity of the condition on the prognosis of pneumonia, including duration of illness, hospital stay and death.


Study design: A Prospective Observational Study.


Place and duration of study. Department of Peads children A ward Khyber Teaching Hospital from jan 2022 to march 2022


Methods: This prospective study enrolled 50 under-five children with pneumonia diagnosis. The haemoglobin levels in the patients were noted at the time of admission, and these results were correlated with other clinical indices, such as severity of pneumonia. The data was gathered through clinical assessment, laboratory investigations, and cultures/endoscopy swabs. Data was analyzed using the SPSS software for statistical analysis with set statistical level of significance at p<0.05 to compare haemoglobin levels and different severities of pneumonia as well as recovery outcomes.


Results: were mean aged 2.8 years (SD = 1.3) at the time of the study and 50 of these patients participated in the current study. Regarding haemoglobin concentrations: The mean value for the group was 9.2 g/dL (standard deviation = 1.5 g/dL). Significantly lower haemoglobin levels predicted a higher severity level of pneumonia, the correlation being – 0. 62, p = 0. 02. Hospital stay of children was significantly longer for children with Haemoglobin levels below 8 g/dL, 5.7 days as compared to 3.2 days of children having Haemoglobin greater than or equal to 8 g/dL (p = 0.03). Absolute anaemia, which was the anaemia with the highest prevalence, was found to double the complication rates such as hypoxia and respiratory distress.


Conclusion: Pneumonia severity and length of stay were significantly higher in children under 5 with lower haemoglobin levels. More awareness of pneumonia and its signs in children may help officials diagnose and treat anaemia in children with pneumonia promptly. The results of the present study underscore a need for recommending haemoglobin levels when working on patients with paediatric pneumonia.


 

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References

1. World Health Organization. Anaemia in children and adolescents: A public health problem. WHO Report. Available at: https://www.who.int. Published 2013.
2. Prendergast, A.J., Kelly, P. Paediatric anaemia and infection: Impact of iron deficiency. Current Opinion in Clinical Nutrition & Metabolic Care. 2015;18(4):417-424.
3. Bhandari, N., et al. Iron deficiency and its impact on pneumonia severity. Journal of Tropical Paediatrics. 2012;58(3):228-234.
4. Pene, F., et al. Anaemia in children with pneumonia and its association with disease outcomes. Critical Care Medicine. 2010;38(5):1227-1233.
5. Kumar, V., et al. Anaemia and its role in respiratory failure in paediatric pneumonia. Paediatric Respiratory Reviews. 2015;16(4):243-249.
6. Agrawal, R., et al. Nutritional intervention and its effect on the severity of pneumonia in children. Indian Journal of Paediatrics. 2014;81(10):1031-1037.
7. Smith, J.H., et al. Haemoglobin levels as a predictor of pneumonia outcomes in children. Paediatric Infectious Disease Journal. 2013;32(5):467-472.
8. Jafari, N., et al. The effect of iron supplementation on pneumonia recovery. Journal of Clinical Nutrition. 2017;68(4):401-406.
9. Baqui, A.H., et al. Anaemia and pneumonia in children: The role of malnutrition in developing countries. International Journal of Infectious Diseases. 2009;13(2):82-88.
10. Rauf, S., et al. Iron supplementation and its impact on pneumonia outcomes in developing countries. Tropical Medicine & International Health. 2017;22(3):295-300.
11. Bhatia, R., & Bhushan, V. Prevalence of anaemia in children under five years of age and its association with clinical outcomes in pneumonia. Asian Journal of Clinical Nutrition. 2016;8(3):42-48.
12. Hossain, M.I., et al. Impact of iron deficiency anaemia on pneumonia and its clinical outcomes in paediatric patients. Journal of Paediatrics and Child Health. 2018;54(6):620-625.
13. Singh, M., & Sharma, V. Clinical implications of anaemia in paediatric pneumonia: A review of current evidence. Journal of Tropical Medicine & Hygiene. 2014;77(2):82-87.
14. Chandra, R., et al. Role of nutritional status in the recovery of children with pneumonia. Journal of Clinical Paediatrics. 2012;51(6):477-481.
15. Gupta, P., et al. Anaemia, pneumonia, and iron deficiency: The role of nutritional intervention in paediatric patients. Nutritional Therapy & Metabolism. 2015;33(4):123-129.
16. Patel, M., et al. Effect of iron deficiency on disease severity in children with pneumonia. Paediatrics and International Child Health. 2017;37(2):101-106.
17. Wilson, J., & Harper, L. Impact of haemoglobin on hospital length of stay in paediatric pneumonia patients. Archives of Disease in Childhood. 2015;100(5):456-462.
18. Brown, C., et al. Anaemia and its association with morbidity in pneumonia: A study in a low-income setting. International Journal of Paediatrics. 2016;4(2):149-154.
19. Sanders, R., et al. Nutritional interventions for managing severe pneumonia in children: A systematic review. Paediatric Health, Medicine and Therapeutics. 2016;7:39-45.
20. Weng, X., & Hwang, H. Haemoglobin and disease outcomes in paediatric pneumonia: A review of the literature. Journal of Paediatric Infection and Immunity. 2014;23(1):56-62.