A Prospective Cohort Study to Assess Soluble FAS Ligand as a Marker of Fetal Programming and an Early Predictor of Feto- Maternal Sensitization in Relation to In Vivo IgE Assessment and cord Blood Mononuclear Cells

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Doha Magdy Emam, Magda Yehia El Seify, Terez Boshra Kamel, Dalia Helmy El-Ghoneimy ,Enas Samir Nabih, Randa Ibrahim Taha , Eman AboElmaaty Mohamed

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Abstract

Background: Allergy is a state of sensitization of the immune system, Programming of disease in fetal and early postnatal life has been hypothesized to be an important mechanism for atopic diseases, peripheral blood mononuclear cell responses to allergen can be detected from as early as 22 weeks gestation, Many immune cells, including neutrophil, monocytes, macrophages and lymphocytes, express Fas (CD95) on their surface. 

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