THE ROLE OF DIETARY FIBER IN PROMOTING GUT HEALTH AND PREVENTING GASTROINTESTINAL DISEASES: A COMPREHENSIVE REVIEW
Main Article Content
Keywords
Abstract
Dietary fibre has a significant influence on gut microbiota and human health. Fibre significantly impacts both gut microbial ecology and host physiology. The article highlights the protective effects of fibre against heart disease, obesity, diabetes, and cancer. It emphasizes fibre's ability to lower LDL cholesterol, blood pressure, and BMI while also promoting feelings of satiety and maintaining intestinal health. SCFAs, produced through fibre fermentation, are identified as pivotal in regulating energy balance and supporting immune function. Furthermore, SCFAs are noted for their role in enhancing the secretion of insulin and maintaining glucose mechanism from the gut-brain axis, particularly in individuals with obesity and diabetes. In short, the review highlights the critical connection between dietary fibre, the composition of gut microbiota, and human health.
References
2. Dreher ML, Dreher ML. Introduction to dietary fiber. Dietary fibre in health and disease. 2018:1-8.
3. Yamashiro Y. Gut microbiota in health and disease. Annals of Nutrition and Metabolism. 2018 Jan 11;71(3-4):242-6.
4. Merenkova SP, Zinina OV, Stuart M, et al. Effects of dietary fibre on human health:2020;20(1):106-13.
5. Rowland I, Gibson G, Heinken A, et al. Gut microbiota functions in the metabolism of nutrients and other food components. European journal of nutrition. 2018 Feb; 57:1-24.
6. Takeoka A, Kimura T, Hara S, et al. Prevalence of irritable bowel syndrome in Japan, China, and South Korea: an international cross-sectional study. Journal of Neuro-gastroenterology and Motility. 2023 Apr 4;29(2):229.
7. Thongpiya J, Charoenngam N, Ponvilawan B, et al. Increased prevalence of gastroesophageal reflux disease among patients with rheumatoid arthritis: a systematic review and meta-analysis. Current Rheumatology Reviews. 2023 Nov 1;19(4):496-503.
8. Bhatia M, Mattoo A. Diverticulosis and diverticulitis: epidemiology, pathophysiology, and current treatment trends. Cureus. 2023 Aug 8;15(8).
9. Yoosuf S, Singh P, Khaitan A, et al. Prevalence of celiac disease in patients with liver diseases: a systematic review and meta-analyses. Official journal of the American College of Gastroenterology| ACG. 2023 May 1;118(5):820-32.
10. Mathers JC. Dietary fibre and health: the story so far. Proceedings of the Nutrition Society. 2023 May;82(2):120-9.
11. Bennet S, Ohman L, Simren M (2015) Gut microbiota as potential orchestrators of irritable bowel syndrome. Gut Liver 9:318–931
12. Betrapally N, Gillevet P, Bajaj J (2016) Changes in the intestinal microbiome and alcoholic and nonalcoholic liver diseases: causes or effects? Gastroenterology 150:1745–1770
13. Allen JM, Mailing LJ, Niemiro GM, et al. (2018) Exercise alters gut microbiota composition and function in lean and obese humans. Med Sci Sport Exer 50:747–757
14. Estruch R, Ros E, Salas-Salvado J, et al. (2018) Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. N Engl J Med 378:34–50
15. Biagi E, Rampelli S, Turroni S, Quercia S, Candela M, Brigidi P (2017) The gut microbiota of centenarians: signatures of longevity in the gut microbiota profile. Mech Age Dev 165:180–184
16. Kelly JR, Kennedy PJ, Cryan JF, Dinan TG, Clarke G, Hyland NP (2015b) Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Front Cell Neurosci 9:392
17. Singh R, Chang H, Yan D, et al. (2017) Influence of diet on the gut microbiome and implications for human health. J Translate Med 15–29
18. La Fata G, Weber P, Mohajeri M (2017) Probiotics and the gut immune system: indirect regulation. Probiotic Antimicrobe Proteins 10(1):11–21
19. Kelly JR, Kennedy PJ, Cryan JF, et al. (2015b) Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Front Cell Neurosci 9:392–411
20. Firouzi S, Haghighatdoost F (2018) The effects of prebiotic, probiotic, and symbiotic supplementation on blood parameters of renal function: a systematic review and meta-analysis of clinical trials. Nutrition 51–52:104–113
21. Gianotti R, Moss A (2017) Fecal microbiota transplantation from Clostridium difficile to inflammatory bowel disease. Gastroenterol Hepatol 13:209–213
22. Li S, Zhu A, Benes V, et al. (2016) Durable coexistence of donor and recipient strains after fecal microbiota transplantation. Science 352(6285):586–589
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Bareera Sana
Student, University Institute of Diet & Nutritional Sciences, The University of Lahore, Pakistan
Nouman Mushtaq
Student, University Institute of Diet & Nutritional Sciences, The University of Lahore, Pakistan
Zainab Hira
Program Assistant, United Nations World Food Programme
Aimen Ramzi
Visiting Faculty, Riphah International University, Gujranwala Campus
Fatima Abid
Assistant Professor, University Institute of Diet & Nutritional Sciences, The University of Lahore, Pakistan
Areeba Sanaullah
Visiting Faculty, Arid University Barani Institute of Sciences, Burewala, Pakistan
Bibi Nusrat Batool
Student, University Institute of Diet & Nutritional Sciences, The University of Lahore, Pakistan \
Saleha Hameed
Assistant Professor, School of Human Nutrition & Dietetics, Minhaj University Lahore, Pakistan