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Dr Abubakkar Alam
Dr Muhammad Zeeshan
Dr Farhan Abbas Baloch
Dr Khalid Shehzad
DR. MaazUllah
Dr Muhammad Awais


Prevalence, Chronic Liver Disease, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome


Background: Chronic liver disease (CLD) has a detrimental effect on the liver, an essential organ with several physiological functions, and has an influence on worldwide healthcare systems. The difficulties related to CLD are impaired by the increasing frequency of metabolic syndrome, especially in non-alcoholic fatty liver disease (NAFLD).

Objective: The objective of this research was to ascertain the metabolic syndrome prevalence in people with CLD, with a particular emphasis on NAFLD.

Methodology: A cross-sectional study of 540 NAFLD patients aged 18-55 in a medical ward of Hayatabad Medical Complex analyzed blood pressure, height, weight, waist circumference, and diagnosed metabolic syndrome and fatty liver using sonology and NCEP-ATP III criteria, respectively. The Mann-Whitney U test in SPSS (version 27) compared risk factor profiles between NAFLD and control cohorts; p<0.05 was significant.

Results: This study found a 20.18% prevalence of NAFLD (n=109) with distinct risk factor profiles compared to controls. NAFLD patients had higher frequencies of both very few (0 or 1, p<0.012) and significantly more (4 p<0.038) risk factors, highlighting the importance of individual profiles for identification and intervention strategies.

Conclusion: This study highlights a significant association between NAFLD and metabolic syndrome, with a prevalence of 20.18% and 33.94%, respectively, in NAFLD patients. Furthermore, NAFLD patients exhibit distinct risk factor profiles compared to controls, emphasizing the importance of individualized assessments for effective identification and management.

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