COLLOIDS VERSUS CRYSTALLOIDS GUIDED BY INFERIOR VENA CAVA COLLAPSIBILITY INDEX IN BIPOLAR TRANSURETHRAL RESECTION PROSTATE; RANDOMIZED CONTROLLED STUDY.

Main Article Content

Mohamed Ahmed Tolba
Mohamed Abdellatif Ghanem
Mohammed Abaalkhayl
Sameh Mohamed El-Sherbiny
Amany Hazem EL-Deeb

Keywords

Transurethral resection prostate, volume overload, colloids, crystalloids, inferior vena cava diameter, fluid challenge

Abstract

BACKGROUNDː Intravenous (IV) fluid replacement during transurethral resection of the prostate (TURP) is still unclear. The purpose of this study was to compare colloids versus crystalloids using inferior vena cava collapsibility index (IVC-CI) to show their impact on the total amount of IV infused fluids.


Methods:  This study included 34 American Society of Anesthesiologists physical status class I and II patients who underwent bipolar TURP. Eligible patients were randomly assigned to two equal groups, crystalloid and colloid (n=17 in each group). The study subjects and the investigators assessing the outcome were blinded to the study group. The primary outcome was the total IV administered fluids volume. Secondary outcomes were  the postoperative serum sodium and potassium, maximum and minimum IVC diameters, IVC-CI, incidence of bradycardia and hypotension, and total IV furosemide dose


RESULTSːI The mean ± SD of the total intravenous infused fluids in colloid group was  355.6 + 151 ml and in the crystalloid group was 602.5 + 200 ml (p = 0.0003). There were no statistical difference between the 2 groups in the serum sodium and potassium at the end of surgery, maximum and minimum IVC diameters, IVC-CI, incidence of bradycardia, incidence of hypotension, total intraoperative ephedrine dose, incidence of intraoperative nausea and/or vomiting, and total IV furosemide dose.


CONCLUSIONSː Colloid volume optimization using US-guided IVC-CI had reduced the total IV fluid volume and achieved volume optimization during TURP surgery with hemodynamic stability preventing fluid overload.

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