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Akansha Arora
Debasish Padhi
Nasir Mahmood
Madhukar Katiyar
Ankita Bajpai


Bipolar disorder, IPSRT, Efficacy, Comparison


Background:  Bipolar disorder is one of the most burdensome mental disorder which is associated with high levels of morbidity and disability in the person who often exhibits frequent recurrences which is attributed to factors such as non-compliance of drug, stressful life events, and disruptions in the social rhythm. Along with pharmacotherapy, effective treatment of bipolar affective disorder (BPAD) should center on principles of social rhythm stabilization, stabilizing the interpersonal relationship, knowing and working on the stressors of the patient. IPSRT acts on the social rhythm as well as the inter-relationship of a person and it can act as a supportive measure in the patients of BPAD.

Aim and objective: This study aimed to evaluate the efficacy of IPSRT in bipolar affective disorder patients.

Material and Methods: A comparative prospective study was carried in the Department of Psychiatry at Rama Medical College Hospital & Research Centre, Kanpur on 44 BPAD patients which was divided into two groups, experimental (IPSRT + pharmacotherapy) and control group (Pharmacotherapy alone). In the IPSRT sessions, we have focused on the patient’s disruptions in social routines, interpersonal problems, and social role transitions which had been associated with affective episodes. The efficacy of IPSRT was measured by comparison of mean scores at baseline & then at 3-month using the Hamilton Depression Rating Scale (HAM-D), Young Mania Rating Scale (YMRS), and Global Assessment of functioning (GAF).

Results and Discussion: There was a considerable improvement in the HAMD-17, YMRS, and GAF scores in both the experimental and the control group, however on comparison at baseline and then at 3 months p-value of HAMD-17(0.001), YMRS(<0.0001) and GAF(0.0001) in experimental group was more significant as compared to that of HAMD-17(0.0063), YMRS(0.0012) and GAF(0.004) of the control group. In those patients who received IPSRT, their social and circadian rhythm were regularized as well as their interpersonal relationships improved.

Conclusion: IPSRT may serve as an add-on therapy along with pharmacotherapy which can help the patients in reduction of psychopathology. It also works on interpersonal and social relationship impairment in Bipolar patients.

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