SPECTRUM OF HISTOPATHOLOGICAL CHANGES IN RUPTURED TUBAL ECTOPIC PREGNANCY AND ITS ASSOCIATION WITH TUBERCULOSIS

Main Article Content

Khalida Depar
Saima Gaffar
Samreen Memon
Pushpa Goswami
Farhana Rajpar
Barkha Goswami

Keywords

Ectopic pregnancy, histopathological findings, ruptured fallopian tube, Tuberculosis

Abstract

Background: Ectopic pregnancy significantly contributes in maternal morbidity and mortality. Fallopian tube is the commonest site of ectopic pregnancy. Genital tuberculosis, which manifest as chronic pelvic pain, pelvic inflammatory infection, infertility, or ectopic pregnancy, affects a significant number of women in underdeveloped countries where tuberculosis is still a serious health concern.


Objective: The aim of this study is to observe Histopathological changes in ruptured fallopian tube and association of tuberculosis in ruptured tubal pregnancy as an etiological factor for ectopic pregnancy.


Method: This descriptive study was conducted on 45 cases of ectopic tubal pregnancy admitted in the department of OBG during the study period. Slides were studied for various histological changes.


Results: Histopathological findings of ruptured fallopian tubes revealed ruptured ectopic  products of conception and few chorionic villi in 16 cases, chorionic villi with decidual tissue  and hemorrhage found in 12 cases, focal mucosal/intramural patches of necrosis seen in 13 cases while, TB granuloma in 04 cases. Tubal walls found invaded by chorionic villi up to serosa in 32 cases while tubal invasion was up to smooth muscle layer in 13 patients.


Conclusion: This study found non-significant association with tuberculosis in ruptured tubal ectopic pregnancy.

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