Assessing the Efficacy of Routine Computed Tomography in Detecting Colorectal Cancer

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Abdullah Hussain Alzahrani, Abeer Abdulrahman Albori, Badar Sulaiman Alkhunaizan, Essam Mohammed Aljubran, Hamoud Rashed Aldaheam, Abdolla Deer Albogamy, Yazeed Saud Almalki, Abdulrahman Adel Alobaydaa

Keywords

Colorectal neoplasm, X-ray computed tomography, Spiral computed tomography, Diagnosis

Abstract

While colonoscopy and CT colonography are highly sensitive methods for detecting colorectal cancer, certain patients may find the necessary bowel preparation and insufflation of gas into the colon challenging. This study evaluates the efficacy of unprepared contrast CT scans in identifying colorectal cancer.


METHODS: A retrospective analysis was conducted on patients who underwent contrast CT scans of the abdomen and pelvis followed by colonoscopy at hospital


RESULTS: Among 96 identified patients who underwent CT prior to colonoscopy, the sensitivity of CT in detecting colorectal cancer was 100% (95% CI: 19.8–100%), with a specificity of 95.7% (95% CI: 88.8–98.6%). The positive predictive value was 33.3% (95% CI: 6.0–75.9%), and the negative predictive value was 100% (95% CI: 94.8–100%).


CONCLUSIONS: A negative non-targeted CT scan for colorectal malignancy typically provides reassurance, but decisions regarding further investigation should be individualized, considering the likelihood of underlying malignancy and patient comorbidities. Nonetheless, positive CT findings usually necessitate subsequent video colonoscopy for assessment

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References

1. Cancer Research UK. Cancer Mortality for Common Cancers. [Online] Available at: http://www.cancerresearchuk.org/cancer-info/cancerstats/mortality/cancerdeaths/ [Accessed: August 2013].
2. Pickhardt, P.J., Choi, J.R., Hwang, I., et al. (2003). Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. New England Journal of Medicine, 349(23), 2191–2200.
3. Phillips, R.K. (2009). Colorectal Surgery. 4th ed. Edinburgh: Saunders.
4. Dixon, A.K., Goldstone, K.E. (2002). Abdominal CT and the Euratom Directive. European Radiology, 12(6), 1567–1570.
5. Ozel, B., Pickhardt, P.J., Kim, D.H., et al. (2010). Accuracy of routine nontargeted CT without colonography technique for the detection of large colorectal polyps and cancer. Diseases of the Colon & Rectum, 53(7), 911–918.
6. Munikrishnan, V., Gillams, A.R., Lees, W.R., et al. (2003). Prospective study comparing multislice CT colonography with colonoscopy in the detection of colorectal cancer and polyps. Diseases of the Colon & Rectum, 46(10), 1384–1390.
7. Mizrahi, M., Mintz, Y., Rivkind, A., et al. (2005). A prospective study assessing the efficacy of abdominal computed tomography scan without bowel preparation in diagnosing intestinal wall and luminal lesions in patients presenting to the emergency room with abdominal complaints. World Journal of Gastroenterology, 11(13), 1981–1986.
8. Uzzaman, M.M., Alam, A., Nair, M.S., et al. (2012). Computed tomography findings of bowel wall thickening: its significance and relationship to endoscopic abnormalities. Annals of the Royal College of Surgeons of England, 94(1), 23–27.
9. Moraitis, D., Singh, P., Jayadevan, R., Cayten, C.G. (2006). Colonic wall thickening on computed tomography scan and clinical correlation. Does it suggest the presence of an underlying neoplasia? American Surgeon, 72(3), 269–271.
10. Thoeni, R.F., Moss, A.A., Schnyder, P., Margulis, A.R. (1981). Detection and staging of primary rectal and rectosigmoid cancer by computed tomography. Radiology, 141(1), 135–138.
11. Ng, C.S., Doyle, T.C., Pinto, E.M., et al. (2002). Evaluation of CT in identifying colorectal carcinoma in the frail and disabled patient. European Radiology, 12(12), 2988–2997.
12. Ganeshan, A., Upponi, S., Uberoi, R., et al. (2007). Minimal-preparation CT colon in detection of colonic cancer, the Oxford experience. Age and Ageing, 36(1), 48–52.
13. Robinson, P., Burnett, H., Nicholson, D.A. (2002). The use of minimal preparation computed tomography for the primary investigation of colon cancer in frail or elderly patients. Clinical Radiology, 57(5), 389–392.
14. Atkin, W.S., Saunders, B.P. (2002). Surveillance guidelines after removal of colorectal adenomatous polyps. Gut, 51, V6–V9.