ASSESSMENT OF CARDIAC AND ELECTROLYTE PROFILE IN CHILDREN INFESTED WITH ASCARIASIS

Main Article Content

Ghanwa Ahmad
Shaaf Ahmad
Muhammad Amir Iqbal
Nabila Roohi

Keywords

Ascariasis, serum electrolytes, HDL-C, LDL-C, VLDL-C

Abstract

Background: Assessment of cardiac and electrolyte profile is of huge medical concerns in children infested with Ascaris lumbricoides. As prolonged deviations in these serum constituents can result in serious health hazards. Methods: For this random case control investigation, 196 children infected with ascariasis were recruited from Lahore (n=58; urban) and Narowal (n=138; rural) districts of Punjab province. Whereas, 200 healthy control (Lahore, n=92; Narowal, n=108) children were also engaged from both districts. Serum electrolytes and lipid profile of both healthy control and ascariasis infected children were assessed.


Methods: Biochemical assessment of lipid profile and serum electrolytes was performed using photochemistry analyzer. Independent student “t” test was applied for statistical interpretation using graph Pad prism version 6.0 software. Results: There was a significant (P < 0.001) decrease in the levels of sodium, chloride and calcium in ascariasis positive children. However, magnesium presented a marked (P < 0.001) increase in infected children as compared to control group. While, no significant difference was observed in levels of Potassium. Cholesterol, HDL-C and LDL-C presented a prominent decline in positive children as compared to control. While, Triglycerides and VLDL-C presented prominent elevation in ascariasis positive children as compared to control. Conclusion: Due to deranged bio chemical profile overall performance of the children infested with ascariasis is compromised.

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