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Joel Lexchin


Health Canada, journal advertisements, Pharmaceutical Advertising Advisory Board, product monograph, surrogate outcomes


Medical journal advertisements make claims for some products based on surrogate outcomes and do not point out that these drugs have not been shown to influence hard clinical outcomes. Some drugs approved on the basis of surrogate outcomes have later had to be withdrawn from the market because of safety problems. Changing the wording in the Product Monograph would require drug manufacturers to note the limits of knowledge about these products.

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