HEPATORENAL SYNDROME: UPDATE

Main Article Content

Katherine Lucía Gordón Reyes
Manuel Rafael Aldás Erazo

Keywords

Hepatorenal syndrome, liver cirrhosis, acute kidney injury, diagnosis, treatment

Abstract

Hepatorenal syndrome is kidney dysfunction due to a decrease in renal flow secondary to chronic liver disease such as liver cirrhosis or acute liver disease. Causing a decrease in the glomerular filtration. In the classification there are two types recognized, AKI, which is characterized by a rapid and progressive deterioration of kidney function, and Non-AKI, by a slow deterioration, but with a better prognosis. This pathology represents a high mortality rate, so timely diagnosis will be key to successful treatment.


General objective: To describe the updates in the diagnostic criteria and treatments of hepatorenal syndrome.


Methods: A narrative literature review was conducted using Science direct, Pubmed, Springer, Scielo/Redalyc and Scopus databases. Scientific articles published during the period 2018-2023 in Spanish and English were included.  Likewise, articles that are in indexed journals and ranked in quartiles according to the SJR (Scimago Institutions Rankins) were selected.


Results: After the results obtained from the literature reviews, there are no specific clinical findings, however, clinical manifestations reflect an underlying advanced liver disease, acute renal injury and circulatory abnormalities.


Conclusions:  it is essential to add Doppler ultrasound studies to the clinical manifestations for the diagnosis, for a comprehensive management in the patient, the optimal treatment is liver transplantation, but it is not always viable, therefore, the pharmacological treatment of vasoconstrictors and albumin is used.

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