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Alina Ahmed
Maria Naseer
Reema Mirza
Hadia Akram
Ramla Moughal
Vinesha Devi


Clinical Patterns, Factors, Melasma, Pregnancy


Adult women often develop melasma, an acquired symmetrical dyschromia affecting photo exposed areas. Dermatology clinics see it often, and its lesions affect patient quality of life.

Objective: To assess the frequency of factors leading to the melasma development in female patients at tertiary care hospital, Karachi.

Place and Duration: This Descriptive Cross-Sectional study was held at the Dermatology Department, Dr. Ruth K.M Pfau Civil Hospital, Karachi - Pakistan for Six months from May 31, 2021 to November 30, 2021.

Methods: Every patient who met the requirements and visited Civil Hospital, Karachi was studied. After discussing the study's process, hazards, and benefits, informed consent was obtained. Brief history about demographic information and duration of melasma was taken. The researcher asked the patients about the factors leading to melasma. The designed proforma was used for data collection and entered electronically for research purpose.

Results: The age of the patients ranged from 20 to 45 years with a median of 31 with interquartile range 14. In distribution of factors leading to melasma, pregnancy was noted in 25 (19.7%), oral contraceptive 18 (14.2%), sunlight exposure 31 (24.4%) while family history of melasma was noted in 44 (34.6%) patients.

Conclusion: It is to be concluded that family history of melasma was found noted as most common factor leading to melasma followed by sunlight exposure and pregnancy. More well-controlled and prospective trials are required to authenticate the current results.



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