ROLE OF PROBIOTICS ON PSYCHIATRIC DISORDERS HOW THEY MODULATE IMMUNE PATHWAY TO IMPROVE BRAIN FUNCTION :THE GUT –BRAIN AXIS

Main Article Content

Dr. Rajesh Singh
Dr. Amrita Chauhan
Dr.Deepak Gawali
Dr.Ashish Saraswat

Keywords

Depression, Gut flora, mental health, Cognitive function.

Abstract

Introduction:-  The central and the enteric nervous system, linking emotional and cognitive centers of the brain with peripheral intestinal functions basically its an bidirectional syatem. The interaction between microbiota and GBA appears to be bidirectional, namely through signaling from gut-microbiota to brain and from brain to gut-microbiota by means of neural, endocrine, immune, and humoral links. Studies showed that distension of the gut resulted in activation of key pathways within the brain and that such pathways are exaggerated in disorders such as irritable bowel syndrome (IBS), a functional gastrointestinal (GI) disorder with dysregulated microbiota-gut-brain axis


 Material And Methods:-Patients attending OPD clinic in   Psychiatry Department  with. Depression ,e ither male or female of Age group -more than 10 years to 70 years of age. Around 100 such patients observed followed by Questionnaire based survey from January  2022 to April  2022.


 Conclusion:- The deteriorating mental health has become a global health issue and has had a major impact on day to day life of the people. Gut flora  is disturbed due to ill food habits of people. Understanding and addressing the mental health issues of patients and general public is important in terms of their efficiency and adaptability towards poor mental health and this is also noteworthy to identify role of probiotics towards promotion of positive mental health.

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