A PROSPECTIVE RANDOMIZED COMPARATIVE STUDY OF PROPOFOL AND LIGNOCAINE IN TERMS OF ATTENUATION OF CARDIOVASCULAR RESPONSES DURING TRACHEAL EXTUBATION
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Abstract
Ivan Magill’s, the Father of endotracheal anaesthesia, and Joun Lundy’s development of balanced anaesthesia were significant milestones that paved the way for modern anesthesia practices.Controlled ventilation techniques have indeed become a cornerstone of anesthesisa care, allowing for safer and more effective management of patients undergoing surgery. The stress response during tracheal extubation can indeed trigger significant hemodynamic changes, posing risks for hypertensive patients and those with CVD. The study was undertaken to compare the effect of Propofol and Lignocaine in attenuating cardiovascular responses during extubation as compared to controls.
References
2. Kern MJ, Gudipati C, Tatineni S, Aquirre F, Serrota H, Deligonul U . Effect of abruptly increased intrathoracic pressure on coronary blood flow velocity in patients. Am Heart J 1990;119:863-70
3. Nishina K, Mikawa K, Maekawa N, Obara H. Attenuation of cardiovascular responses to tracheal extubation : comparision of verapamil,Lignocaine and verapamil-Lignocaine combination . Anesth Analg 1997;85,1005-10
4. Lai JIANG, Xiano-jian WAN, Hua Xu, Jin-Jun BIAN, Wen-Jun HAN, Ke –Ming ZHU et al. effect of diltiazem and Lignocaine on arterial pressure or heart rate and quality of extubation in patient undergoing uvulopalato-pharyngoplasty. Journal of medical colleges of PLA 2007;22: 4, 230-233
5. Nho J S, Lee S Y, Kang J M, Kim M C, Choi Y K, Shin O Y et al. Effect of maintaining a remifentanil infusion on the recovering profiles during emergence from anaesthesia and tracheal extubation, Br J Anaesth 2009; 103: 6, 817-821
6. Kovac A L, Masiongate A. Comparison of nicardipine versus esmolol in attenuating the hemodynamic responses to anaesthesia emergence and extubation,Journal of cardiothoracic and vascular anaesthesia 2007;21:1, 45-50
7. Nishina K, Mikawa K, Maekawa N, fentanyl attenuates cardiovascular responses to tracheal extubation, Acta aneasthesiologica scandinavica 1995;39:1, 85-89
8. Robinson BJ, Eben TJ, O’Brien TJ, Colinco M D, Muzi M . Mechanisms whereby Propofol mediates peripheral vasodilators in human,sympatho-inhibition or direct vascular relaxation? , Anesthesiology 1997;86:64-72
9. Wallin G, Cassuto J, Hogstrom S, Faxen A, Rimback G, Hedner T. Effects of Lignocaine infusion on the sympathetic response to abdominal surgery. Anesth Analg 1987;66:1008-13
10. Lowrie A, Johnston PL, Fell D, Robinson SL. Cardiovascular and plasma catecholamine responses at tracheal extubation. Br J Anaesth 1992;68:261-3.
11. Vaziri MTM, Jouybar R, Vaziri N M, Vaziri N M, Panah A. Attenuation of cardiovascular responses and upper airway events to tracheal extubation by low dose Propofol. Iran Red Crescent Med J 2013 Apr;15(4):298-301
12. Coriat P, Mundler O, Bousseau D, Fauchet M, Rous A C, Echter E, et al. Response of left ventricular ejection fraction to recovery from general anesthesia: measurement by gated radionuclide angiography. Anesth Analg 1986;65:593-600.
13. Wellwood M, Aylmer A, Teasdale S, Fremes S, Ivanov J, Madonik M, et al. Extubation and myocardial ischemia. Anesthesiology 1984;61(3A):A132
14. Vaziri MTM, Jouybar R, Vaziri N M, Vaziri N M, Panah A. Attenuation of cardiovascular responses and upper airway events to tracheal extubation by low dose Propofol. Iran Red Crescent Med J 2013 Apr;15(4):298-301
15. Bidwai AV, Bidwai VA, Rogers CR, Stanley TH. Blood-pressure and pulse-rate responses to endotracheal extubation with and without prior injection of Lignocaine. Anesthesiology 1979;51:171-3
16. Wallin G, Cassuto J, Hogstrom S, Faxen A, Rimback G, Hedner T. Effects of Lignocaine infusion on the sympathetic response to abdominal surgery. Anesth Analg 1987;66:1008-13

