“MALARIA IN OUTDOOR SETTINGS: CORRELATING CLINICAL MANIFESTATION WITH LABORATORY FINDINGS”
Main Article Content
Keywords
Malaria, Parasitemia, Fever Duration, Severe Malaria, Diagnostic Markers, Neutrophil-to-Lymphocyte Ratio.
Abstract
Background: Malaria is a serious health problem in the world, and its clinical presentation is determined by the extent of severity. The present paper has tried to establish the relationship between the manifestation of malaria in the clinical setting and laboratory findings, including parasitemia and the duration of fever.
Objective: To identify the relationship that exists between the level of parasitemia and duration spent in a febrile condition among patients with malaria at various levels of severity.
Methods: The study was a cross-sectional study conducted in the period between April and September 2024. Most patients with malaria were classified as mild, moderate, or severe patients. Laboratory findings and clinical manifestations, including the degrees of parasitemia and hematological figures, were observed. Correlations were determined by statistical analysis.
Results: The levels of parasitemia had a positive relationship with fever duration. The malaria cases characterized by severe cases exhibited a significant increase in levels of parasitemia (>50,000 parasites/µL) and extended duration of fever. The severe malaria was also linked to high neutrophil-lymphocyte ratios.
Conclusion: Detection and treatment at an early stage are critical in malaria control. The use of parasitemia and inflammatory markers is helpful in measuring the severity of the disease.
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Kalpana
House Officer, KVSS site Hospital SESSI, Landhi Hospital, Karachi, Pakistan
Anoksha
House Officer, KVSS site Hospital SESSI, Landhi Hospital, Karachi, Pakistan
Jeevan Dass
House Officer, KVSS site Hospital SESSI, Landhi Hospital, Karachi, Pakistan
Komal
House Officer, KVSS site Hospital SESSI, Landhi Hospital, Karachi, Pakistan
Kelash Kumar
House Officer (MBBS), Jinnah PostGraduate Medical College (JPMC), Karachi, Pakistan
Zainab Ismail
House Officer, KVSS site Hospital SESSI, Landhi Hospital, Karachi, Pakistan
Hina Khan
Professor, Deputy Director Research and Postgraduate Affairs, Deputy Director Research and Postgraduate Labs, Pakistan