STUDY OF THE MATERNAL AND FETAL OUTCOME IN PREGNANCIES COMPLICATED WITH HYPERTENSIVE DISORDERS OF PREGNANCY: A STUDY AT MGM HOSPITAL AND RESEARCH CENTRE, PATNA.
Main Article Content
Keywords
Hypertension, Maternal outcome, Foetal outcome, Low birth weight, Eclampsia, Severe pre-eclampsia.
Abstract
Hypertension is the most common medical disorder encountered during pregnancy, occurring in 5-10% of pregnancies. Women with hypertensive disorders of pregnancy (HDP) are all at increased risk of complications antenatally and in the puerperium.
Objective: This study aims to determine the maternal and perinatal outcomes of hospitalized pregnant cases with hypertension.
Methods: This was a 18 months prospective cross sectional study conducted in MGM Hospital and Research centre,Patna . Maternal and Perinatal outcomes were compared among the HDP groups and results were analysed and tabulated by SPSS version, using chi square method.
Results: 42.5% of the patients had Gestational Hypertension. 32.5% of the patients had Preeclampsia. 11.5% of the patients had Chronic Hypertension In Pregnancy. 8.0% of the patients had PECH. 5.5% of the patients had Eclampsia, PECH had the largest proportion of Maternal Morbidity like PPH and Acute renal failure, and Eclampsia had the largest proportion of Maternal Morbidity( Placental Abruption, Pulmonary Edema, HELLP ,DIC). Maternal Mortality was observed in 1 (0.5%) Patients of eclampsia probably due to intracerebral haemorrhages. Eclampsia had the largest proportion of APGAR Score Category at 5 minutes: <7 and Gestational Hypertension had the largest proportion of APGAR Score Category at 5 minutes: ≥7. Eclampsia had the largest proportion of Neonatal Outcome as NICU Admission and IUD, Neonates 1.2% of the patients in the group of Gestational Hypertension had Died. 6.2% of the patients in the group of Preeclampsia had Died. 9.1% of the patients in the group of Eclampsia had Died.
Conclusion: A substantial burden of maternal and perinatal morbidity and mortality is associated with hypertensive disorders of pregnancy, more so in eclampsia and severe preeclampsia group as compared to gestational hypertension and mild pre-eclampsia.
References
2. Sibai BM, Mercer B, Sarinoglu C. Severe preeclampsia in the second trimester: recurrence risk and long-term prognosis. Am J Obset Gynecol. 1991, 165(5 Pt 1):1408– 1412.
3. Barton JR, O‘brien JM, Bergauer NK et al. Mild gestational hypertension remote from term: progression and outcome. Am J Obstet Gynecol. 2001, 184(5):979–983.
4. Sibai BM, Sarinoglu C, Mercer BM. Eclampsia. VII. Pregnancy outcome after eclampsia and long-term prognosis. Am J Obstet Gynecol. 1992, 166(6 Pt 1):1757– 1761.
5. Maynard SE, Min JY, Merchan J et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest. 2003, 111(5):649–658
6. Matthys LA, Coppage KH, Lambers DS et al. Delayed postpartum preeclampsia: an experience of 151 cases. Am J Obstet Gynecol. 2004, 190(5):1464–1466.
7. .Osungbade KO, Ige OK. Public health perspectives of preeclampsia in developing countries: implications for health system strengthening. Journal of Pregnancy. 2011, 6.
8. Audibert F, Boucoiran I, An N et al. Screening for preeclampsia using first- trimester serum markers and uterine artery Doppler in nulliparous women. Am J Obstet Gynecol. 2010, 203(4): 383.e1-383.e8
9. Franklin University Simple test can help predict and diagnose preeclampsia. Science daily. 2010
10. Perry IJ, Beevers DG. The definition of preeclampsia. Br J Obstet and Gynecol. 1994, 101:587-91
11. Patel R, Baria H, Patel HR et al. A study on pregnancy induced hypertension and foetal outcome among patients with PIH at a tertiary care hospital, Valsad. Int J Community Med Public Health 2017;4:4277-81.
12. Ye C, Ruan Y, Zou L et al. The 2011 Survey on Hypertensive Disorders of Pregnancy (HDP) in China: Prevalence, Risk Factors, Complications, Pregnancy and Perinatal Outcomes. PLoS ONE 2014;9(6): e10018
13. Xavier IM, Simões ACZ, Oliveira R de, Barros YE, Sarmento ACA, Medeiros KS de, et al. Maternal-fetal outcomes of women with hypertensive disorders of pregnancy. Revista da Associação Médica Brasileira [Internet]. 2023 ;69:e20230060.
14. Joshi P, Kathaley M, Borade S et al. Maternal and Perinatal Outcome in Hypertensive Disorders of Pregnancy - A Retrospective Study. MVP Journal of Medical Sciences 2018; 5(1):87-91
15. .Sharma C, Gupta S, Tyagi M et al. Maternal & Perinatal outcome in Hypertensive Disorders of Pregnancy in a Tertiary Care Hospital in Northern India. Obstet Gynecol Int J. 2017, 6(6): 00229.
16. Bernardes TP, Zwertbroek EF, Broekhuijsen K et al. Delivery or expectant management for prevention of adverse maternal and neonatal outcomes in hypertensive disorders of pregnancy: an individual participant data meta- analysis. 29 world congress on Ultrasound Obstet Gynecol. 2019.
17. Panda S, Das R, Sharma N, Das A, Deb P, Singh K. Maternal and Perinatal Outcomes in Hypertensive Disorders of Pregnancy and Factors Influencing It: A Prospective Hospital-Based Study in Northeast India. Cureus. 2021 Mar 18;
18. Seyom E, Abera M, Tesfaye M et al. Maternal and fetal outcome of pregnancy related hypertension in Mettu Karl Referral Hospital, Ethiopia. J Ovarian Res. 2015, 8:10.
