ASSOCIATION OF HYPERURICEMIA WITH THE PRESENCE AND SEVERITY OF CORONARY ARTERY DISEASE IN PATIENTS UNDERGOING CORONARY ANGIOGRAPHY
Main Article Content
Keywords
Hyperuricemia, Coronary artery disease, Gensini score, Angiography, Cardiovascular risk.
Abstract
Introduction: Coronary artery disease (CAD) is on the list of leading causes of morbidity and mortality in the world. Hyperuricemia is no longer a benign disease or metabolic disorder since studies have found an increasing correlation of hyperuricemia and cardiovascular risk and the severity of CAD.
Objective: To identify the relationship that exists between hyperuricemia and the severity and occurrence of CAD among patients who were undergoing coronary angiography in a tertiary care hospital.
Materials and Methods: A cross-sectional study was conducted from July, 2024 to December, 2024 at the Rashid Latif Medical College, Lahore. A sample size of 250 patients who received coronary angiography was involved. The level of serum uric acid and the severity of CAD based on Gensini score were determined. Data analysis was performed using SPSS 26.
Results: The prevalence of hyperuricemia was 41.6 percent. An increased uric acid was linked to increased prevalence of the triple vessel disease and a much higher percentage of mean Gensini scores in the normouricemic patients.
Conclusion: Hyperuricemia was significantly associated with each and severity of CAD which justifies its position as a mere adjunctive risk stratification marker.
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Muhammad Ahmad Raza Butt
Associate Professor, Rashid Latif Medical College, Lahore, Pakistan
Tahir Mumtaz
Post Fellow Interventional Cardiology, Sindh Institute of Cardiovascular Disease Sukkur, Pakistan
Raja Mahendar Paul Nankani
Specialist General Practitioner, (AKMC Abu Dhabi UAE)/ Jinnah Postgraduate Medical Center Hospital Karachi, Pakistan
Muhammad Tayyab
Assistant Professor, Rashid Latif Medical University Lahore, Pakistan
Atif Ahmed Khan
Assistant Professor, Intervention Cardiology, Sindh Institute of Cardiovascular Diseases Hyderabad, Sindh, Pakistan
Faisal Ahmed
Assistant Professor, Department of Cardiology, Hamdard University Hospital, Pakistan