PREVALENCE OF HEPATITIS B AND C INFECTIONS AMONG HOSPITALIZED RESPIRATORY PATIENTS: A TERTIARY CARE ANALYSIS FROM MULLANA, HARYANA
Main Article Content
Keywords
Hepatitis B, Hepatitis C, Respiratory infections, Tertiary care, Haryana
Abstract
Hepatitis B virus (HBV) and Hepatitis C virus (HCV) co-infections in respiratory patients represent a significant healthcare challenge in North India. The intersection of chronic liver disease and respiratory pathology creates complex clinical scenarios requiring specialized attention.
Objectives: To determine the prevalence of HBV and HCV infections among hospitalized respiratory patients at a tertiary care center in Mullana, Haryana, and analyze associated risk factors and clinical outcomes.
Methodology: A cross-sectional observational study was conducted from January 2019 to December 2020 among 384 hospitalized respiratory patients aged 18-75 years. Data collection included demographic profiles, clinical presentations, laboratory investigations including HBsAg and anti-HCV antibodies, and chest imaging findings. Statistical analysis was performed using SPSS version 26.0.
Results: The prevalence of HBV infection was 12.8% (n=49) and HCV infection was 8.1% (n=31) among respiratory patients. Co-infection rate was 2.3% (n=9). Chronic obstructive pulmonary disease (COPD) patients showed higher hepatitis prevalence (18.4%) compared to pneumonia patients (9.2%). Mortality rate was significantly higher in hepatitis-positive respiratory patients (15.8% vs 6.2%, p<0.001).
Conclusion: The study reveals substantial hepatitis burden among respiratory patients in Haryana, necessitating routine screening protocols and integrated management approaches in tertiary care settings.
References
2. Singh P, Sharma R. Regional variations in hepatitis C prevalence across Punjab and Haryana: a comprehensive survey. J Viral Hepat. 2020;27(8):642-650.
3. Mehta N, Patel K, Shah D. Clinical outcomes of hepatitis-positive patients in respiratory intensive care units. Crit Care Med. 2021;49(3):445-452.
4. Liu L, Wang Y, Zhang Z. Hepatitis infections and respiratory disease progression: a systematic review and meta-analysis. Respirology. 2020;25(7):634-645.
5. Agarwal R, Kumar A. Hepatitis burden assessment in Haryana's healthcare facilities: gaps and opportunities. Indian J Public Health. 2019;63(2):178-184.
6. World Health Organization. Global hepatitis report 2021. Geneva: WHO Press; 2021.
7. Rathi S, Kamble P, Joshi SR. Epidemiology of viral hepatitis in India: current status and future directions. Natl Med J India. 2020;33(3):134-141.
8. Tandon BN, Acharya SK, Tandon A. Epidemiology of hepatitis B virus infection in India. Gut. 2019;68(Suppl 2):II5-II8.
9. Ministry of Health and Family Welfare. National Viral Hepatitis Control Program: Progress Report 2021. New Delhi: Government of India; 2021.
10. Indian Council of Medical Research. Guidelines for prevention and management of viral hepatitis in healthcare settings. New Delhi: ICMR; 2020.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr. Mineshkumar Uttambhai Patel
Assistant Professor, Department of General Medicine, M. M. Institute of Medical Sciences and Research, Mullana, Ambala, Haryana
Mr. Alok Pritam
Statistician cum Tutor, Department of Community Medicine, Netaji Subhash Medical College & Hospital, Bihta, Patna, Bihar, India
Dr. Arunkumar Rameshwarprasad Varun
Professor, Department of Community Medicine, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India
Dr. Shivanand M Gundalli
Associate Professor, Department of Pathology, M M Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India