SLOW GROWING PROLIFERATIVE SQUAMOUS CELL CARCINOMA OF LOWER BACK REGION - A CASE REPORT AND LITERATURE REVIEW
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Keywords
SLOW GROWING, PROLIFERATIVE, SQUAMOUS CELL,CARCINOMA, LOWER BACK,
Abstract
Cutaneous squamous cell carcinoma (cSCC) is a prevalent non-melanoma skin cancer, predominantly found on sun-exposed areas. However, rare presentations in protected regions such as the lower back are often associated with chronic irritation, non-healing ulcers, or prior indigenous treatments, leading to delayed diagnosis and management.
Aim and Objective: To study the slow growing proliferative squamous cell carcinoma of lower back region - a case report and literature review
Case Summary: We present the case of a 70-year-old female with a 2-year history of an ulceroproliferative lesion on the lower back, initially mismanaged with indigenous therapies. Histopathological analysis confirmed well-differentiated squamous cell carcinoma. Imaging revealed subcutaneous infiltration without nodal involvement. The patient underwent wide local excision (WLE) with flap reconstruction. Histopathology confirmed negative margins, and the postoperative course was uneventful.
Conclusion: This case underscores the importance of early diagnosis, imaging, and surgical management of chronic skin ulcers suspicious for malignancy, especially in elderly patients with comorbidities. Emphasis on community education and timely biopsy of non-healing ulcers is vital for early intervention, particularly in rural settings where indigenous treatments are common.
References
2. Que SKT, Zwald FO, Schmults CD. Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging. J Am Acad Dermatol. 2018;78(2):237-47.
3. Alam M, Armstrong A, Baum C, et al. Guidelines of care for the management of cutaneous SCC. J Am Acad Dermatol. 2018;78(3):560-78.
4. Moura DL, Madureira AJ, Soares J, et al. Marjolin ulcers: a study of 18 cases. Ann Plast Surg. 2014;73(3):300-4.
5. Labbé JL, Perrot JL, Vignes S. Marjolin ulcers: 22 cases. Ann Dermatol Venereol. 2020;147(6-7):434-41.
6. Ohtsuka M, Yamazaki S, Saito M, et al. Ulcerative SCC in elderly: outcomes in Japan. J Dermatol. 2022;49(6):581-6.
7. Breuninger H, Eigentler T, Bootz F, et al. Prognostic factors in cSCC. J Clin Oncol. 2021;39(10):1036-44.
8. Lee K, Kim JH, Park SM, et al. Flap reconstruction after excision of cSCC. Arch Plast Surg. 2023;50(2):129-36.
9. Veness MJ. High-risk cSCC of skin: perineural invasion. Aust J Dermatol. 2021;62(1):3-10.
10. Dhiwakar M, Yashoda HT, et al. Clinical spectrum of Marjolin’s ulcer in Indian patients. J Clin Diagn Res. 2022;16(4):PC01-PC04.
11. Nouri K, Rivas MP, Cervantes J. Skin cancer reconstruction. Dermatol Surg. 2022;48(4):456-64.
12. Maheshwari N, Singh R, Patel N. Clinical profile and outcomes of cutaneous SCC in rural India. Indian J Dermatol. 2024;69(1):22-6.
13. Zhu H, Li Q, Wang T. Imaging evaluation of cSCC with CECT. Chin Med J. 2023;136(12):1470-5.
14. Sharma D, Yadav S, Roy R. Histopathological grading and prognostic implications in cSCC. Int J Med Res. 2024;8(2):145-50.
15. Hassan S, Rajan A, Thomas S. Role of comorbidities in cSCC outcomes. BMC Dermatol. 2025;25(1):22.
16. Rao M, Bhatia R, Sharma V. Malignant transformation of chronic ulcers in elderly rural patients: A prospective observational study. Indian J Surg Oncol. 2024;15(1):30–6.
17. Pillai SK, Joseph L, Mehra N. Delayed detection of trunk and gluteal squamous cell carcinomas: A multicenter cohort analysis. J Geriatr Oncol. 2025;16(2):102–8.
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Dr. Swarnava Chanda
Assistant Professor1, Department of Surgery (Surgical Oncology), Dr. BS Kushwah Institute of Medical Sciences, Uttar Pradesh, India.
Dr. Amrita Sinha
Associate Professor2, Department of Pathology, Rama Medical College Hospital and Research Centre, Uttar Pradesh, India.
Dr. Kanwal Kamboj
Associate Professor3, Department of Forensic Medicine, Rama Medical College Hospital and Research Centre, Uttar Pradesh, India.
Dr. Dinesh Kumar Singh
Assistant Professor4, Department of Surgery, Rama Medical College Hospital and Research Centre, Uttar Pradesh, India.
Dr. Razi Shahid
Assistant Professor5*, Department of Anesthesiology, Era’s Lucknow Medical College & Hospital, Uttar Pradesh, India.