EVALUATION OF HEMATOLOGICAL PROFILE OF NEONATES BORN TO PREECLAMPTIC AND NORMOTENSIVE MOTHERS
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Keywords
Neonates, hematological, preeclamptic, normotensive, group etc.
Abstract
Introduction- Preeclampsia, a hypertensive disorder of pregnancy, can adversely affect neonatal outcomes. So this study aims to evaluate hematological parameters in neonates born to preeclamptic versus normotensive mothers to identify potential hematologic alterations linked to intrauterine hypoxia and placental insufficiency.
Material and method- The present study was a hospital-based, comparative cross-sectional study conducted on 200 term neonates, categorized into two groups. Group A constituted 100 neonates born to preeclamptic mothers diagnosed whereas group B had 100 neonates born to healthy, normotensive mothers. Umbilical cord blood was analyzed for hemoglobin, hematocrit, WBC, ANC, platelet count, and red cell indices. Data were analyzed using SPSS v20, with significance set at p<0.05.
Result- Neonates born to preeclamptic mothers had significantly lower gestational age, birth weight, RBC count, and platelet count, but higher hemoglobin, hematocrit, nRBCs, and reticulocytes (all p<0.01). Polycythemia (14% vs. 4%) and thrombocytopenia (46% vs. 12%) were significantly more frequent in the preeclamptic group. NICU admissions, IUGR, neonatal sepsis, and prematurity were also more common. No significant differences were observed in WBC, MCV, MCH, MCHC, or Apgar scores.
Conclusion- Maternal preeclampsia significantly impacts neonatal hematological profiles due to intrauterine hypoxia and placental insufficiency. Routine screening enables early detection and management of complications like thrombocytopenia or polycythemia, improving neonatal outcomes and guiding perinatal care in high-risk pregnancies.
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Dr. Raj Kishor Kumar
Senior Resident, Department of Pathology, Phulo Jhano Medical College and Hospital, Dumka, Jharkhand, India
Dr. Vidyanand Kumar
Senior Resident, Department of Pathology, Medinirai Medical College and Hospital, Daltonganj, Jharkhand, India
Dr. Mukesh Kumar
Senior Resident, Department of Community Medicine. Phulo Jhano Medical College and Hospital, Dumka, Jharkhand, India
Dr. Gaur Chandra Gorain
Junior Resident Academic, Department of Pathology. Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India