ULTRASONOGRAPHIC EVALUATION OF ENDOMETRIAL THICKNESS AND PATTERN IN ABNORMAL UTERINE BLEEDING.
Main Article Content
Keywords
Abnormal uterine bleeding; Transvaginal ultrasound; Endometrial thickness; Endometrial pattern; Histopathology.
Abstract
Background: Abnormal uterine bleeding (AUB) is a common gynecologic problem where early identification of endometrial pathology is important, especially in perimenopausal and postmenopausal women. Transvaginal ultrasound (TVUS) is widely used as a first-line test to assess endometrial thickness (ET) and detect structural causes that may require further evaluation.
Methods: A cross-sectional observational study was conducted among 130 women (≥18 years) presenting with AUB, excluding pregnancy, prior malignancy, and recent hormone use. All participants underwent TVUS with ET measurement and endometrial pattern assessment, and endometrial sampling/hysteroscopy was performed when indicated by clinical or sonographic suspicion.
Results: Mean age was 41.8 ± 10.6 years; 61.5% were reproductive age, 23.1% perimenopausal, and 15.4% had postmenopausal bleeding. On TVUS, perimenopausal women more commonly had ET >12 mm (46.7%), while 50% of postmenopausal bleeders had ET >4 mm; predominant patterns were homogeneous (46.2%), heterogeneous (32.3%), cystic (13.8%), and focal lesions (7.7%). Final diagnoses were benign/normal in 42.3%, polyps in 15.4%, hyperplasia without atypia in 13.8%, EIN/atypical hyperplasia in 4.6%, and carcinoma in 3.1%, with higher mean ET in premalignant/malignant categories.
Conclusion: TVUS-based assessment of ET together with standardized morphological descriptors provides a practical triage approach in women with AUB to identify those needing biopsy or hysteroscopy while avoiding unnecessary invasive testing in low-risk cases. These findings support continuing TVUS as the initial imaging modality in AUB evaluation, with escalation based on risk profile and suspicious ultrasound features.
References
2. National Institute for Health and Care Excellence (NICE). Heavy menstrual bleeding: assessment and management (NG88). London: NICE; 2018 (updated 2021). Available from: https://www.nice.org.uk/guidance/ng88/chapter/recommendations
3. American College of Obstetricians and Gynecologists (ACOG). The role of transvaginal ultrasonography in evaluating the endometrium of women with postmenopausal bleeding. Committee Opinion No. 734. Obstet Gynecol. 2018;131(5):e124-e129.
4. Leone FPG, Timmerman D, Bourne T, et al. Terms, definitions and measurements to describe the sonographic features of the endometrium and intrauterine lesions: a consensus opinion from the International Endometrial Tumor Analysis (IETA) group. Ultrasound Obstet Gynecol. 2010;35(1):103-112.
5. Park YR, Lee SW, Kim YH, et al. Endometrial thickness cut‑off value by transvaginal ultrasonography for screening of endometrial pathology in premenopausal and postmenopausal women. Obstet Gynecol Sci. 2019;62(6):445-453.
6. Khare A, Bansal R, Sharma P, et al. Endometrial cut‑off thickness as predictor of endometrial pathology in perimenopausal women with abnormal uterine bleeding. J Midlife Health. 2022;13(1):27-33.
7. Priya S, Kumari S, Singh P, et al. Sonographic and histopathological correlation and evaluation of endometrium in perimenopausal women with abnormal uterine bleeding. Int J Reprod Contracept Obstet Gynecol. 2016;5(12).

