A COMPARATIVE STUDY OF LEVOBUPIVACAINE AND ROPIVACAINE FOR PERIOPERATIVE ANALGESIA IN PATIENTS UNDERGOING UPPER LIMB SURGERY BY SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK
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Keywords
Levobupivacaine, Ropivacaine, Brachial Plexus Block.
Abstract
Background: According to clinical research, levobupivacaine and ropivacaine are more beneficial in regional anaesthesia procedures because they have fewer negative effects on the central nervous system and cardiovascular system. Regarding their comparative clinical statistics, there is less information accessible. Levobupivacaine and ropivacaine have only been compared in a small number of studies for brachial plexus blocks.
Methods: This was a randomized parallel group double-blind controlled study conducted over a period of 12 months involving 64 ASA Grade-I or Grade-II status patients belonging to the age group 18-60 years undergoing orthopedic surgery of the elbow, forearm, and hand. Group A (n=35): received 30 ml of 0.5% levobupivacaine; group B (n=35): received 30 ml of 0.5% ropivacaine. Both the groups received supraclavicular brachial plexus block with nerve stimulation.
Results: Regarding the duration of sensory and motor block, the maximum and minimum times of duration of sensory and motor block were much higher in group A than in group B, and the differences were statistically significant. Post-operative VAS (Visual Analogue Score) scale after 1 hour, 6 hours, and 12 hours after completion of surgery. After 1 hour, the VAS score was 0 in both groups. After 6 hours, group A had a maximum score of 2 and a minimum score of 0. But in group B, the maximum score was 2 and the minimum score was 0. 12 hours postoperatively in group A, maximum and minimum VAS were 3 and 0, respectively, whereas in group B, maximum and minimum VAS were 10 and 5, respectively.
Conclusion: Levobupivacaine in supraclavicular brachial plexus block improves the quality of postoperative analgesia and the duration of sensory and motor block without producing significant adverse effects in patients undergoing orthopedic procedures of the elbow, forearm, and hand in comparison to ropivacaine.
References
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Dr. Subrata Bisai
Assistant Professor, Department of Anaesthesiology, Raiganj Government Medical College, Raiganj. West Bengal, India.
Dr. Subir Kumar Brahma
Assistant Professor, Department of Anaesthesiology, Malda Medical College, Malda, West Bengal, India.
Dr. Pradip Kumar Mandal
Associate professor, Department of Anaesthesiology, Malda Medical College, Malda, West Bengal, India.