TRANSFEROSOMES: A BREAKTHROUGH IN TARGETED DRUG DELIVERY
Main Article Content
Keywords
Targeted drug delivery, Transfersomes, Transdermal, Medication etc
Abstract
Transferosomes are a revolutionary development in the realm of targeted drug delivery, providing a viable way around the drawbacks of traditional drug delivery methods. Phospholipids, surfactants, and an edge activator make up these ultra-deformable vesicles, which allow them to pass easily through biological barriers like the skin. Transferosomes' special structure enables them to encapsulate medications that are both lipophilic and hydrophilic, guaranteeing a wide range of therapeutic uses. Transferosomes' content is responsible for their remarkable flexibility and deformability, which enable them to pass across small intercellular gaps without compromising their integrity. This property minimizes systemic side effects and increases patient compliance by facilitating a controlled and prolonged release of the medication in addition to enhancing its penetration and absorption.
Transferosomes can also be designed to target particular tissues or cells, which increases the therapeutic efficacy of the medications that are encapsulated while lowering off-target effects.
The effectiveness of transferosomes in delivering a range of medications, such as anti-inflammatory medicines, peptides, proteins, and genetic material, has been shown in both clinical and preclinical investigations. Their application encompasses transdermal, topical, and systemic routes, demonstrating their adaptability in managing a range of medical illnesses, including infectious infections, diabetes, and cancer. To sum up, transferosomes offer a flexible, effective, and patient-friendly method of drug administration, marking a substantial advancement in targeted drug delivery. The capabilities and uses of transferosomes are expected to be substantially enhanced by ongoing research and development in this area, opening the door to more individualized and efficient therapeutic interventions.
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Priya Chaturvedi
Research Scholar, Integral University, Department of Pharmaceutics, Kursi Road Lucknow -226026, Uttar Pradesh, India
Dr Vaseem A Ansari
Professor, Department of Pharmaceutics, Integral University, Kursi Road Lucknow -226026, Uttar Pradesh, India
Dr Shaheen Sultana
Professor, Galgotias University, Department of Pharmaceutics, Greater Noida- 203201, Uttar Pradesh, India