CLINICAL SIGNIFICANCE OF SULCAL AND GYRAL VARIATIONS IN THE HUMAN SUPEROLATERAL SURFACE OF CEREBRAL CORTEX: A CADAVERIC ANALYSIS.
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Abstract
Introduction: The human cerebral cortex exhibits anatomical variability, particularly in the folding patterns of its gyri (ridges) and sulci (grooves). While these variations are generally considered benign, their potential clinical significance remains unclear. This study investigates the prevalence and types of sulcal and gyral variations in the superolateral cerebral cortex and explores their possible influence on neurological function.
Methods: A cadaveric analysis was conducted on 56 human brains obtained from the Department of Anatomy, GIMSH, Durgapur. The superolateral surfaces of both hemispheres were meticulously examined to identify and document any deviations from standard sulcal and gyral patterns. Variations were categorized based on established anatomical classification systems.
Results: The study identified sulcal and gyral variations in 70% of the examined brains. These variations included Superfrontal Gyral, Infro Frontal Gyral, Post Central Gyrul, Sylvian fissure bifurcation, atypical frontal gyri. Statistical analysis explored potential correlations between specific variations and documented medical history of the donors, focusing on neurological conditions.
Conclusion: This cadaveric analysis revealed a significant prevalence of sulcal and gyral variations in the human superolateral cortex. Further investigation is needed to determine the precise clinical implications of these variations. Future studies with larger cohorts and detailed clinical data could elucidate potential associations with neurological function and dysfunction.
References
2. Naidich T, Tang C, Ng J, et al. Surface anatomy of the cerebrum. In: Naidich T, Castillo M, Cha S, et al, editors. Imaging the brain. Philadelphia: Elsevier Inc; 2013. p. 127–53.
3. Ulmer S. Neuroanatomy and cortical landmarks. In: Ulmer S, Jansen O, editors. fMRI: Basics and clinical applications. 3rd edition ed. Switzerland: Springer Nature; 2020. p. 5–13.
4. Sibilla L. Functional anatomy of the major lobes. In: Agarwal N, Port J, editors. Neuroimaging: anatomy meets function. Switzerland: Springer International Publishing; 2018. p. 81–99.
5. Cho S, Kurokawa R, Hagiwara A, et al. Localization of the central sulcus using the distinctive high signal intensity of the paracentral lobule on T1-weighted images. Neuroradiology 2021;64(2):289–99.
6. Su S, Yang N, Gaillard F. Invisible cortex sign: a highly accurate feature to localize the inferolateral central sulcus. J Med Imaging Radiat Oncol 2019; 63(4):439–45.
7. Hill VB, Cankurtaran CZ, Liu BP, et al. A practical review of functional MRI Anatomy of the language and motor systems. AJNR Am J Neuroradiol 2019;40(7): 1084–90.
8. Naidich T, Yousry T. Functional Neuroanatomy. In: Stippich C, editor. Clinical functional MRI: Presurgical functional neuroimaging. Berlin-Heidelberg: Springer-Verlag; 2007. p. 53–86.
9. Wagner M, Jurcoane A, Hattingen E. The U sign: tenth landmark to the central region on brain surface reformatted MR imaging. AJNR Am J Neuroradiol 2013;34(2):323–6.
10. Shah A, Jhawar SS, Goel A. Analysis of the anatomy of the Papez circuit and adjoining limbic system by fiber dissection techniques. J Clin Neurosci 2012; 19(2):289–98.
11. Duprez TP, Serieh BA, Raftopoulos C. Absence of memory dysfunction after bilateral mammillary body and mammillothalamic tract electrode implantation: preliminary experience in three patients. AJNR Am J Neuroradiol 2005;26(1):195–7.
12. Naidich TP, Valavanis AG, Kubik S. Anatomic relationships along the low-middle convexity: Part I-- normal specimens and magnetic resonance imaging. Neurosurgery 1995;36(3):517–32.
13. Destrieux C, Terrier LM, Andersson F, et al. A practical guide for the identification of major sulcogyral structures of the human cortex. Brain Struct Funct 2017;222(4):2001–15.
14. Naidich TP, Kang E, Fatterpekar GM, et al. The insula: anatomic study and MR imaging display at 1.5 T. AJNR Am J Neuroradiol 2004;25(2):222–32.
15. Courchesne E, Press GA, Murakami J, et al. The cerebellum in sagittal plane–anatomic-MR correlation: 1. the vermis. AJRAmJRoentgenol1989;153(4):829–35.
16. Press GA, Murakami J, Courchesne E, et al. The cerebellum in sagittal plane–anatomic-MR correlation: the cerebellar hemispheres. AJR Am J Roentgenol 1989;153(4):837–46.
17. Press GA, Murakami JW, Courchesne E, et al. The cerebellum: 3. anatomic-MR correlation in the coronal plane. AJR Am J Roentgenol 1990;154(3): 593–602.
18. Monte Bispo RF, Casado Ramalho AJ, Buarque de Gusmao LC, et al. Cerebellar vermis: topography and variations. Int J Morphol 2010;28(2):439–43.
19. Naidich T, Brightbill T. Systems for localizing frontoparietal gyri and sulci on axial CT and MRI. Int J Neuroradiol 1996; 2:313–38.
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Dr. Rupa Chhapawal
Dr. Rupa Chhapawal, Professor, Department of Anatomy, Sri Aurobindo Medical College and P.G. Institute, Indore, MP, India
Dr. Bandita Medhi
Dr. Bandita Medhi, Professor, Department of Anatomy, Sri Aurobindo Medical College and P.G. Institute, Indore, MP, India
Dr. Manoj Kumar
Dr. Manoj Kumar, School of Pharmaceutical, Dr. KN Modi University, Jaipur, Rajasthan, India
Dr. Abhimanyu Kumar
Dr. Abhimanyu Kumar, Assistant Professor, Department of Anatomy, Gouri Devi Institute of Medical Sciences & Hospital, Durgapur, West-Bengal, India