COMPARATIVE STUDY OF CYANOACRYLATE TISSUE ADHESIVE AND SUBCUTICULAR SUTURE FOR WOUND CLOSURE FOLLOWING BREAST SURGERY
Main Article Content
Keywords
Cyanoacrylates, Breast, Tissue Adhesives, Sutures
Abstract
BACKGROUND: This study aims to compare subcuticular sutures and cyanoacrylate tissue adhesive for skin closure. There have been several studies on the benefits of cyanoacrylate tissue adhesive. This tissue adhesive is said to provide superior cosmetic results compared to traditional sutures. This study analyses the results when cyanoacrylate adhesive is used as a substitute for subcuticular sutures.
METHODOLOGY: The prospective interventional study was conducted from August 2022 to May 2024. The study included 68 patients, all of whom met the required inclusion criteria. The outcome of the procedure was detected at day 0, 3, 7, 10, and 30. post-procedural wound complications and cosmetic results were measured at various evaluations.
RESULTS: A total of 68 patients participated in the study, 34 patients in the control group and 34 patients in the study group. Using an adhesive reduced the amount of wound site infection but increased wound gaping. However, no difference in cosmetic outcome after 1 month was observed between cyanoacrylate and subcuticular sutures.
CONCLUSION: Cyanoacrylate tissue adhesive is a good alternative to traditional subcuticular sutures. Patients experience less discomfort when the wound is closed using cyanoacrylate, and a better solvent result can be obtained. Thus, tissue adhesive can be considered for routine treatment procedures in the hospital.
References
10.18203/2349-2902.isj20160659
2. Lakoma A, Kim ES. Minimally invasive surgical management of benign breast lesions. Gland surgery. 2014 May;3(2):142. 10.3978/j.issn.2227-684X.2014.04.01
3. Singer AJ, Quinn JV, Clark RE, Hollander JE, Group TS. Closure of lacerations and incisions with octyl cyanoacrylate: a multicenter randomized controlled trial. Surgery. 2002 Mar 1;131(3):270-6. 10.1067/msy.2002.121377
4. Chow A, Marshall H, Zacharakis E, et al. Use of tissue glue for surgical incision closure: a systematic review and meta-analysis of randomised controlled trials. Journal of the American College of Surgeons. 2010 Jul 1;211(1):114-25
10.1016/j.jamcollsurg.2010.03.013
5. Maw JL, Quinn JV, Wells GA et al. l. A prospective comparison of octyl cyanoacrylate tissue adhesive and suture for the closure of head and neck incisions. The Journal of Otolaryngology. 1997 Feb 1;26(1):26-30. A Prospective Comparison of Octylcyanoacrylate Tissue Adhesive and Suture for the Closure of... | Journal of Otolaryngology | EBSCOhost
6. Toriumi DM, O'Grady K, Desai D, Bagal A. Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery. Plastic and reconstructive surgery. 1998 Nov 1;102(6):2209-19. Plastic and Reconstructive Surgery (lww.com)
7. Gennari R, Rotmensz N, Ballardini B, et al. A prospective, randomized, controlled clinical trial of tissue adhesive (2-octyl cyanoacrylate) versus standard wound closure in breast surgery. Surgery. 2004 Sep 1;136(3):593-9. 10.1016/j.surg.2004.02.015
8. Nipshagen MD, Hage JJ, Beekman WH. Use of 2-octyl-cyanoacrylate skin adhesive (Dermabond) for wound closure following reduction mammaplasty: a prospective, randomized intervention study. PlastReconstr Surg. 2008;122(1):10-18. 10.1097/PRS.0b013e318171524b
9. Freitas RD, Becker TS, Rahal RM, Paulinelli RR, Soares LR. Surgical breast incisions treated with 2-octyl-cyanoacrylate versus intradermal nylon suture: a randomized clinical trial. Revista do ColégioBrasileiro de Cirurgiões. 2019 Dec 20;46. 10.1590/0100-6991e-20192286
10. Zheng K, Gu Q, Zhou D, Zhou M, Zhang L. Recent progress in surgical adhesives for biomedical applications. Smart Materials in Medicine. 2022 Jan 1;3:41-65. 10.1016/j.smaim.2021.11.004
11. Quinn JV, Osmond MH, Yurack JA, Moir PJ. N-2-butylcyanoacrylate: risk of bacterial contamination with an appraisal of its antimicrobial effects. The Journal of emergency medicine. 1995 Jul 1;13(4):581-5.
10.1016/0736-4679(95)80025-5
12. Bao Z, Gao M, Sun Y, Nian R, Xian M. The recent progress of tissue adhesives in design strategies, adhesive mechanism and applications. Materials Science and Engineering: C. 2020 Jun 1;111:110796. 10.1016/j.msec.2020.110796
13. ALICANDRI-CIUFELLI M, Piccinini A, Grammatica A, Molteni G, Spaggiari A, Di Matteo S, Tassi S, Ghidini A, Izzo L, Gioacchini FM, Marchioni D. Aesthetic comparison between synthetic glue and subcuticular sutures in thyroid and parathyroid surgery: a single-blinded randomised clinical trial. Acta Otorhinolaryngologica Italica. 2014 Dec;34(6):406. 0392-100X-34-406.pdf (nih.gov)
14. Chen TH, Choi CL, Suen TK, Kwong A. A prospective randomized controlled trial of octyl cyanoacrylate tissue adhesive and standard suture for wound closure following breast surgery. Hong Kong Medical Journal. 2016. 10.12809/hkmj154513
15. Musham A, Samuel EM, Sahoo AK, Elamurugan TP, Manwar AS. Comparison of Tissue Adhesive Glue with Subcuticular Absorbable Suture for Skin Closure Following Thyroid Surgery: A single-blinded randomised controlled trial. Sultan Qaboos University Medical Journal. 2023 Feb;23(1):42. 10.18295/squmj.1.2022.005
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr Neha Babar
Junior resident 3rd year, Department of General Surgery, Shri B.M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Dr Tejaswini Vallabha
Professor, Department of General Surgery, Shri B.M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Dr Girish Kullolli
Professor, Department of General Surgery, Shri B.M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Dr Shruti Sheelin
Assistant professor, Department of General Surgery, Shri B.M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.