FREQUENCY OF MULTI VESSEL DISEASE AND ASSOCIATED IN-HOSPITAL OUTCOMES IN PATIENTS PRESENTING WITH STEMI AND UNDERGOING PRIMARY PCI
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Keywords
Hospital Outcomes, Multi-Vessel Disease, Myocardial Infarction, STEMI
Abstract
OBJECTIVES: To determine the frequency of multivessel disease in patients presenting with ST-segment evaluation myocardial infarction (STEMI) at NICVD Karachi.
- To determine the frequency of in-hospital outcomes associated with multivessel disease in STEMI patients.
STUDY DESIGN AND SETTING: The descriptive case series study was conducted at the Cardiology Emergency Department and Cath Lab during the period of September 28, 2022, to March 25, 2023, at the National Institute of Cardiovascular Disease in Karachi, Pakistan.
MATERIALS AND METHODS: All patients who fulfilled the inclusion criteria and visited NICVD, Karachi, were included in the study. Informed consent was obtained after explaining the procedure, risks, and benefits of the study. All the patients underwent primary PCI and were observed for 48 hours post-PCI in the ward to assess the in-hospital outcomes of the associated multivessel disease. All the collected data was entered into the proforma attached at the end and used electronically for research purposes.
RESULTS: The mean ± SD of age was 55.36±8.40 years. In the distribution of gender, 107 (70.9%) were male while 44 (29.1%) were female. Multi-vessel disease was noted in 75 (49.7%) patients. In the distribution of in-hospital outcomes, contrast-induced nephropathy was noted in 10(13.3%) patients, pulmonary edema 3(4.0%), cardiogenic shock 2(2.7%), need for a ventilator 4(5.3%), heart block 3(4.0%) while mortality was documented in 7(9.3%) patients.
CONCLUSION: It is to be concluded that contrast-induced nephropathy was a common in-hospital outcome of multivessel disease in STEMI patients, followed by mortality and a need for a ventilator. Furthermore, our findings outline the need for future research to investigate those factors that could be considered to be at higher risk of adverse in-hospital outcomes.
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