PHARMACOLOGICAL ACTION OF DIFFERENT HERBAL ENDODONTIC IRRIGANTS AND THEIR EFFICACY AS IRRIGANTS IN PULPECTOMY OF PRIMARY TEETH: A LITERATURE REVIEW.
Main Article Content
Keywords
Antimicrobial efficacy, chelating ability, herbal endodontic irrigants, pulp tissue dissolution capability
Abstract
For millennia, humans have been using traditional medicine to cure & prevent various illnesses. Different herbal products & their numerous beneficial properties have been promoted use in both the medical & dental fields. The pulpectomy procedure is directed to eliminate microorganisms from the primary teeth' root canal space, which ultimately carries out the associated healing of apical tissue. Complex root canal morphology, presence of lateral & accessory canals, continuously resorbing root, and primary teeth demand particular attention. Conventional irrigants are synthetically made chemical substances that pose some difficulty during the procedure as the physical & chemical properties of irrigants are less tolerated by pediatric patients. Post-treatment complications & certain adverse reactions are also well-documented with conventional irrigants. An irrigation solution has been chosen considering its antimicrobial efficacy, ability to remove smear layer & ability to dissolve pulp tissue. In this regard, Kaul & Raut instituted a classification of herbal endodontic irrigants. Different bioactive components in herbal agents and their mechanism of action inside the root canals are the potential for their use in pulpectomy procedures. In this context, this narrative review aims to discuss the pharmacodynamics of different herbal irrigants & their efficacy as root canal irrigants in the field of pediatric dentistry.
References
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14. Tartari T, Guimaraes BM, Amoras LS, Duarte MAH, Silva e Souza PAR, Bramante CM. Etidronate causes minimal changes in the ability of sodium hypochlorite to dissolve organic matter. Int Endod J. 2015;48:399-404.
15. Prabhakar J, Senthikumar M, Priya MS, Mahalakshmi K, Sehgal PK, Sukumaran VG. Evaluation of Antimicrobial Efficacy of Herbal Alternatives (Triphala & Green tea polyphenols), MTAD & 5% Sodium Hypochlorite against Enterococcus faecalis Biofilm Formed on Tooth Substrate: An In Vitro Study. J Endod. 2010;36:83-86.
16. Cogulou D, Uzel A, Oncag O, Eronat C. PCR-based identification of selected pathogens associated with endodontic infections in deciduous & permanent teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:443-9.
17. Lewis K, Ausubel FM. Prospects for plant-derived anti-bacterials.Nat. Biotechnol.2006;24(12):1504-1507.
18. Chowdhury AR. Essential oils of the leaves of Eupatorium odoratum L. from Shillong (N.E.). J.Ess. Oil-Bear. Plan.2002;5:14-18.
19. Ambareen Z, Konde S, Raj SN, Kumar NC. Antimicrobial efficacy of herbal extracts. Int J Oral Health Dentistry 2015;1:108.
20. Abascal K, Yarnell E. Herbs & drug resistance. Part 2- clinical inplications of research on microbial resistance to antibiotics. Altern Complementary Therapies 2002;8:284-90.
21. Purva Parvin Kale & Ambar W Raut, A proposed classification system for herbal endodontic irrigants,J Conserv Dent, 2021 May-Jun; 24(3);293-295.
22. Yoshida M, Fukushima H, Yamamoto K, Ogawa K, Toda T, Sagawa H. Correlation between clinical symptoms on microorganisms isolated from root canals with periapical pathosis. J Endod 1987; 13 (1):24-28.
23. Rana V, Baba SM, Pandey A. Bacteriology of infected deciduous root canal: a review. People’s J Scientific Res 2009 Jul; 2(2):45-48.
24. Cogulu D, Uzel A, Oncag O, EronatC. PCR-based identification of selected pathogens associated with endodontic infections in deciduous & permanent teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106(3):443-449.
25. HuYw, Zhu M, Liu Z. A bacteriology analysis from infected root canals of human deciduous teeth. Shanghai J stomatal 1998;7(3):143-146.
26. Capello C, Fischer U, Hungerbuhler K. What is green solvent? A comparative framework for the environmental assessment of solvents.2007;ISSUE 9.
27. Novak KM,ed. (2002). Drug Facts and Comparisons 9 56th ed.0. St. Louis, Missouri: Wolters Kluwer Health. P. 2345. ISBN 978-1-57439-110-7.
28. ‘’Azadiracta indica ‘’ Germplasm Resources Information Network. Agriculyural Research Service, United States Department of Agriculture. Retrived 9 June 2017.
29. Reddy RR, Kumari K, Lokanath O, Mamatha S, Reddy D. Antimicrobial activity of Azadiracta Indica (neem) leaf, bark & seed extracts. Inter J Res Phytochem Pharmacol 2013;3:1-4.
30. Biswas K, Chattopadhyay I, Banerjee RK, Bandyopadhay U. Biological activities & medical properties of neem ( Azadiracta indica). Curr Sci 2001;82:1336-45.
31. Bohora A, Heghe V, Kokate S. Comparison of the antibacterial efficiency of neem leaf extract & 2% sodium hypochlorite against E. faecalis, C. albicans & mixed culture -an in vitro study. Endodontology 2010; 22: 8-12.
32. Dutta A, Kundabala M. Comparative antimicrobial efficacy of Azadiracta indica irrigant with standard endodontic irrigants: a preliminary study. J Conserv Dent 2014;17:133-7.
33. Ravishankar P, Laksmi T, Kumar SA. Ethano-butanical approach for root canal treatment-an update. J Conserv Dent 2014;17:133-7.
34. Mohammad A. Alzohairy. Therapeutics role of Azadiracta indica & their active constituents in diseases prevention & treatment. Evid Baesd Complement Alternat Med. 2016.
35. Dutta A, Kundabala M. Antimicrobial efficacy of endodontic irrigants from Azadiracta indica :An in vitro study. Acta Odontol Scand. 2013;71:1594-8.
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Aug 23, 2024
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Dr. Manna Haque Akhanda, Dr. Fahmida Siddiqua, Dr. Dilara Jahan, Dr. Ikramul Ahmed, Dr. Md. Zahid Hossain, Dr. Anam Ahmed, & Dr. Shahidul Islam. (2024). PHARMACOLOGICAL ACTION OF DIFFERENT HERBAL ENDODONTIC IRRIGANTS AND THEIR EFFICACY AS IRRIGANTS IN PULPECTOMY OF PRIMARY TEETH: A LITERATURE REVIEW. Journal of Population Therapeutics and Clinical Pharmacology, 31(8), 1332-1345. https://doi.org/10.53555/7w754y88
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Author Biographies
Dr. Manna Haque Akhanda
MS (Pediatric dentistry), Ex- HOD, D. pharmacology, Ex- HOD, Pediatric dentistry Community Based Medical College Bangladesh, Dental Unit; Consultant, BD Lab health center
Dr. Fahmida Siddiqua
MS (Pediatric dentistry), Lecturer; Pediatric dentistry, Dhaka Dental College
Dr. Dilara Jahan
DDS, MCPS (Dental surgery), Medical officer, Pediatric dentistry Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Dr. Ikramul Ahmed
MPH, Associate Professor & Head, Department of Children Preventive & Community Dentistry
Dr. Md. Zahid Hossain
MS (Pediatric dentistry), Lecturer, Department of Periodontology & Oral pathology Dhaka Dental College
Dr. Anam Ahmed
MPH, MPhil, Associate Professor, Dept. of Dental Public Health University Dental College, Dhaka
Dr. Shahidul Islam
DDS, MS (Pediatric dentistry), Associate Professor, Pediatric Dentistry University Dental College, Dhaka
How to Cite
Dr. Manna Haque Akhanda, Dr. Fahmida Siddiqua, Dr. Dilara Jahan, Dr. Ikramul Ahmed, Dr. Md. Zahid Hossain, Dr. Anam Ahmed, & Dr. Shahidul Islam. (2024). PHARMACOLOGICAL ACTION OF DIFFERENT HERBAL ENDODONTIC IRRIGANTS AND THEIR EFFICACY AS IRRIGANTS IN PULPECTOMY OF PRIMARY TEETH: A LITERATURE REVIEW. Journal of Population Therapeutics and Clinical Pharmacology, 31(8), 1332-1345. https://doi.org/10.53555/7w754y88