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Tariq Rafique
Muhammad Bilal Yusuf
Ammar Ahmed
Madiha Iftikhar
Dr. Med Jeyatheepan Jeyaretnam
Aksa Alina Joy


infection with Staphylococcus aureus, staphylococcal scalded skin syndrome, and staphylococcal toxic shock syndrome


Background: Staphylococcus aureus produces epidermolytic toxins leading to Staphylococcal Scalded Skin Syndrome (SSSS), characterized by blistering, erythematous cellulitis, and skin peeling. It primarily affects adults and some pediatric patients.

Methods: This review outlines the clinical foundation, etiopathogenesis, complications, treatments, and anticipated future developments of SSSS.

Results: SSSS is a toxin-mediated infection requiring wound care, antibiotic therapy, and supportive care to reduce mortality. A multidisciplinary approach involving dermatologists, infectious disease specialists, and surgeons is crucial due to its differential diagnoses, including toxic epidermal necrolysis, adverse drug reactions, and Steven Johnson syndrome.

Conclusion: Understanding SSSS's clinical aspects and management strategies is essential. Further research is needed to enhance treatment efficacy and patient outcomes.

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