ENHANCING DIABETES MELLITUS (DM2) CARE THROUGH PHARMACEUTICAL INTERVENTIONS: A REVIEW OF THE LITERATURE
Main Article Content
Keywords
Type 2 Diabetes Mellitus, Diabetes Complications, Pharmaceutical Assistance, Adherence To Drug Treatment
Abstract
Background: Diabetes mellitus (DM) poses significant public health challenges globally, including in Pakistan, where it ranks as the fourth leading cause of death. Chemists play a vital role in diagnosing, treating, and managing type II diabetes mellitus (DM2) patients.
Methods: A systematic review was conducted using medical databases SCIELO, LILACS, and VHL. A total of 1190 scholarly articles were screened, resulting in the inclusion of 31 investigations. Ten studies met the inclusion criteria.
Results: Pharmaceutical interventions have demonstrated efficacy in reducing the risk of complications associated with poorly controlled DM2 and promoting patient adherence to medication regimens. Pharmacy specialists are integral to DM2 patient care, contributing to glycemic control, adherence to dosage guidelines, lifestyle modifications, and medication selection based on necessity, efficacy, safety, and affordability.
Conclusion: The involvement of chemists in managing DM2 is crucial for improving patient outcomes and addressing the significant public health burden associated with the condition. Pharmacist-led interventions contribute to better disease control and patient adherence, ultimately reducing morbidity and mortality rates associated with DM2.
References
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19. Hias, J., Defieuw, L., Vanassche, T., Verhamme, P., & Van der Linden, L. (2024). Therapy and guideline adherence at a multidisciplinary hypertension clinic: A prospective, observational study. Vascular Pharmacology, 154, 107271.
20. Jaber, D., Al Shihab, A., & Tamimi, L. N. (2024). Efficacy and Safety of Pharmacist-Managed NSAIDs Deprescribing: A Jordanian Outpatient Study. Journal of Clinical Pharmacy and Therapeutics, 2024.
21. Katare, M. R. K., & Ugale, S. REVIEW ON CLINICAL PHARMACY.
22. Keller, M. S., Qureshi, N., Mays, A. M., Sarkisian, C. A., & Pevnick, J. M. (2024). Cumulative Update of a Systematic Overview Evaluating Interventions Addressing Polypharmacy. JAMA Network Open, 7(1), e2350963-e2350963.
23. Khardali, A., Syed, N. K., Alqahtani, S. S., Qadri, M., Meraya, A. M., Rajeh, N., . . . Gunfuthi, S. (2024). Assessing medication adherence and their associated factors amongst type-2 diabetes mellitus patients of Jazan Province, Saudi Arabia: A single-centre, cross-sectional study. Saudi Pharmaceutical Journal, 32(1), 101896.
24. Kozlowski, S., Tworkoski, E., Dharmarajan, S., Flowers, N., Kwist, A., Shangguan, S., . . . Kelman, J. A. (2024). Dispensing pharmacy chains and direct anticoagulants: Potential associations with patient outcomes. Pharmacoepidemiology and Drug Safety, 33(2), e5749.
25. Le, K. D. R., Le, K., & Foo, F. (2024). The Impact of Glucagon-like Peptide 1 Receptor Agonists on Obstructive Sleep Apnoea: A Scoping Review. Pharmacy, 12(1), 11.
26. Majd, Z., Mohan, A., Fatima, B., Johnson, M. L., Essien, E. J., & Abughosh, S. M. (2024). Trajectories of adherence to ACEI/ARB medications following a motivational interviewing intervention among Medicare Advantage beneficiaries in Texas. Patient Education and Counseling, 119, 108073.
27. Masad, S. M., Alshahrani, A. M., Alshubayni, A. M., Aldosar, A. M., Masad, M. M., & Ali, S. I. (2024). Evaluating medication adherence and its impact on glycemic control in elderly diabetic patients: a cross-sectional analysis. Pakistan Heart Journal, 57(1), 1-7.
28. Mellot, M., Jawal, L., Morel, T., Fournier, J.-P., Tubach, F., Cadwallader, J.-S., . . . Zerah, L. (2024). Barriers and Enablers for Deprescribing Glucose-Lowering Treatment in Older Adults: A Systematic Review. Journal of the American Medical Directors Association.
29. Mills, W. R., Howard, S., Pitzen, K., Smitherman, J., Cole, L., Wolfram, J., . . . Poltavski, D. (2024). A Novel Home-Based Medication Management Program and Its Influence on Hospitalization Rates among Home Health Care Recipients. Journal of the American Medical Directors Association, 25(1), 155-157. e151.
30. Mohajan, D., & Mohajan, H. K. (2024). Oral Hypoglycaemic Agents: Non-Insulin Medications for Type 2 Diabetes Patients. Innovation in Science and Technology, 3(1), 23-31.
31. Moon, J., Chladek, J. S., Wilson, P., & Chui, M. A. (2024). Clinical decision support systems in community pharmacies: a scoping review. Journal of the American Medical Informatics Association, 31(1), 231-239.
32. Neeland, I. J., Bourges-Sevenier, B., Dazard, J.-E., Albar, Z., Landskroner, Z., Tashtish, N., . . . Nennstiel, M. (2024). Second-year results from CINEMA: A novel, patient-centred, team-based intervention for patients with Type 2 diabetes or prediabetes at high cardiovascular risk. American Journal of Preventive Cardiology, 17, 100630.
33. Nyamagoud, S. B., Swamy, A. H. V., & Kangrali, B. (2024). Assessment of Health-Related Quality of Life and Associated Factors among Type 2 Diabetes Mellitus Patients Attending a Tertiary Care Hospital. Ind. J. Pharm. Edu. Res, 58(1), 326-332.
34. Oh, R. C., Murphy, K. C., Jenks, C. M., Lopez, K. B., Patel, C. M. A., Scotland, E. E., & Khanna, M. (2024). Low-Carbohydrate and Ketogenic Dietary Patterns for Type 2 Diabetes Management. Federal Practitioner, 41(1).
35. Othman, N., Lean, Q. Y., Neoh, C. F., Abd Wahab, M. S., Noor, N. M., Lim, S. L., & Wong, Y. Y. Trajectory, Perceived Causes and Efforts in Diabetes Self-management: A Qualitative Study Among Young People With Type 2 Diabetes Mellitus and Caregivers.
36. Parsons, K. A., Ekong, G. J., Charbonneau, M. S., Laisure, M. R., & Capoccia, K. L. (2024). Diabetes distress among people with type 2 diabetes in a pharmacist-run community care clinic. American Journal of Health-System Pharmacy, 81(1), e9-e11.
37. Ranganath, T., & Panda, P. S. (2024). ASSESSMENT OF DIABETIC LITERACY AND PERCEIVED GAPS IN HEALTHCARE PROVISION AMONG TYPE 2 DIABETES NEPHROPATHY PATIENTS: A MIXED METHOD STUDY IN A TERTIARY CARE CENTER IN BANGALORE. Int J Acad Med Pharm, 6(1), 310-314.
38. Sperl-Hillen, J. M., Haapala, J. L., Dehmer, S. P., Chumba, L. N., Ekstrom, H. L., Truitt, A. R., . . . Pankonin, M. A. (2024). Protocol of a patient randomised clinical trial to improve medication adherence in primary care. Contemporary Clinical Trials, 136, 107385.
39. Tokita, J., Lam, D., Vega, A., Wang, S., Amoruso, L., Muller, T., . . . Zabetian, A. (2024). A Real-World Precision Medicine Program Including the KidneyIntelX Test Effectively Changes Management Decisions and Outcomes for Patients With Early-Stage Diabetic Kidney Disease. Journal of Primary Care & Community Health, 15, 21501319231223437.
40. Torres-Novellas, B., Rius, P., Figueiredo-Escribá, C., Mariño, E. L., & Modamio, P. (2024). Drug-Related Problems Detected in Complex Chronic Patients by Community Pharmacists of Catalonia: Perception of the Person-Centred Approach Necessity. Paper presented at the Healthcare.
41. Zhang, R.-T., Liu, Y., Sun, C., Wu, Q.-Y., Guo, H., Wang, G.-M., . . . Bai, X.-Y. (2024). Predicting Hypoglycemia in Elderly Inpatients with Type 2 Diabetes: The ADOCHBIU Model.
2. Alatawi, A. D., Elgendy, M. O., Sayed, A. M., Mallhi, T. H., Khan, Y. H., Alzarea, A. I., . . . Alanazi, A. S. (2024). Evaluation of Utilisation and Satisfaction of Patients towards Pharmaceutical Services in Hospitals: A Descriptive Study from Al-Jouf Region of Saudi Arabia. Ind. J. Pharm. Edu. Res, 58(1), 355-363.
3. Albai, O., Braha, A., Timar, B., Sima, A., Deaconu, L., & Timar, R. (2024). Assessment of the Negative Factors for the Clinical Outcome in Patients with SARS-CoV-2 Infection and Type 2 Diabetes Mellitus. Diabetes, Metabolic Syndrome and Obesity, 271-282.
4. Althubyani, A. N., Gupta, S., Tang, C. Y., Batra, M., Puvvada, R. K., Higgs, P., . . . Thomas, J. (2024). Barriers and Enablers of Diabetes Self-Management Strategies Among Arabic-Speaking Immigrants Living with Type 2 Diabetes in High-Income Western Countries Systematic Review. Journal of Immigrant and Minority Health, 1-14.
5. Baas, G., Crutzen, S., Smits, S., Denig, P., Taxis, K., & Heringa, M. (2024). Process evaluation of a pharmacist‐led intervention aimed at deprescribing and appropriate use of cardiometabolic medication among adult people with type 2 diabetes. Basic & clinical pharmacology & toxicology, 134(1), 83-96.
6. Badi, S., Suliman, S. Z., Almahdi, R., Aldomah, M. A., Marzouq, M. E., Ibrahim, E. E. M., . . . Ibrahim, M. I. M. (2024). The Impact of Clinical Pharmacist Diabetes Education on Medication Adherence in Patients with Type 2 Diabetes Mellitus: An Interventional Study from Khartoum, Sudan. Journal of Personalized Medicine, 14(1), 74.
7. Berthoumieux, A., Linke, S., Merry, M., Megliola, A., Juusola, J., & Napoleone, J. (2024). Long-Term Results of a Digital Diabetes Self-Management and Education Support Program Among Adults With Type 2 Diabetes: A Retrospective Cohort Study. The Science of Diabetes Self-Management and Care, 26350106231221456.
8. Burton, D., Gysel, S., & Tsuyuki, R. T. (2024). Why we need to incorporate obesity medicine into community pharmacies (Vol. 157, pp. 3-6): SAGE Publications Sage CA: Los Angeles, CA.
9. CG, A.-O., Adibe, M., Ukwe, C., & Aguwa, C. (2030). Journal of Pharmaceutics and Therapeutics The Impact of Family Support on Medication Adherence and Glycemic Control of Type 2 Diabetes Outpatients in a Nigerian Tertiary Hospital.
10. Chen, C., Zhou, Y., Xu, J.-Y., Song, H.-Y., Yin, X.-W., & Gu, Z.-J. (2024). Effect of Peer Support Interventions in Patients with Type 2 Diabetes: A Systematic Review. Patient Education and Counseling, 108172.
11. Chui, M. A., Berbakov, M. E., Gilson, A. M., Stone, J. A., Lehnbom, E. C., Hoffins, E. L., & Ford II, J. H. (2024). Engineering Resilient Community Pharmacies: Exploring an Integrative Approach to Medication Safety.
12. Corvaisier, M., & Annweiler, C. (2024). The invaluable contributions of clinical pharmacy to geriatric medicine. Maturitas, 180.
13. Dibenedetto, J. R., Cetrone, M., Antonacci, M., Cannone, D. P., Antonacci, S., Bratta, P., . . . Tricarico, D. (2024). The Community Pharmacy as a Study Center for the Epidemiological Analysis of the Population Vaccination against SARS-CoV-2: Evaluation of Vaccine Safety and Pharmaceutical Service. Pharmacy, 12(1), 16.
14. Ekenberg, M., Qvarnström, M., Sundström, A., Martinell, M., & Wettermark, B. (2024). Socioeconomic factors associated with poor medication adherence in patients with type 2 diabetes. European Journal of Clinical Pharmacology, 80(1), 53-63.
15. Eshiet, U. I., Igwe, C. N., & Ogbeche, A. O. (2024). Comparative assessment of medication knowledge among ambulatory patients: A cross-sectional study in Nigeria. Exploratory Research in Clinical and Social Pharmacy, 13, 100388.
16. Espírito-Santo, M., Santos, S., & Estêvão, M. D. (2024). Digital Solutions Available to Be Used by Informal Caregivers, Contributing to Medication Adherence: A Scoping Review. Pharmacy, 12(1), 20.
17. Fornwald, C. R., Russo-Alvarez, G., Pantalone, K. M., Zeleznikar, E., Parker, M., McCorkindale, N., . . . Hermiller, T. (2024). Endocrinology/Primary Care Pharmacy Collaboration vs Endocrinology Care Alone in Patients With Type 2 Diabetes and A1c> 9%. Journal of Pharmacy Technology, 87551225231224251.
18. Hall, H. M., Ashley, K. C., Schadler, A. D., & Naseman, K. W. (2024). Evaluation of a Pharmacist-Managed Diabetes Transitions of Care Medication Management Clinic. The Science of Diabetes Self-Management and Care, 26350106231221463.
19. Hias, J., Defieuw, L., Vanassche, T., Verhamme, P., & Van der Linden, L. (2024). Therapy and guideline adherence at a multidisciplinary hypertension clinic: A prospective, observational study. Vascular Pharmacology, 154, 107271.
20. Jaber, D., Al Shihab, A., & Tamimi, L. N. (2024). Efficacy and Safety of Pharmacist-Managed NSAIDs Deprescribing: A Jordanian Outpatient Study. Journal of Clinical Pharmacy and Therapeutics, 2024.
21. Katare, M. R. K., & Ugale, S. REVIEW ON CLINICAL PHARMACY.
22. Keller, M. S., Qureshi, N., Mays, A. M., Sarkisian, C. A., & Pevnick, J. M. (2024). Cumulative Update of a Systematic Overview Evaluating Interventions Addressing Polypharmacy. JAMA Network Open, 7(1), e2350963-e2350963.
23. Khardali, A., Syed, N. K., Alqahtani, S. S., Qadri, M., Meraya, A. M., Rajeh, N., . . . Gunfuthi, S. (2024). Assessing medication adherence and their associated factors amongst type-2 diabetes mellitus patients of Jazan Province, Saudi Arabia: A single-centre, cross-sectional study. Saudi Pharmaceutical Journal, 32(1), 101896.
24. Kozlowski, S., Tworkoski, E., Dharmarajan, S., Flowers, N., Kwist, A., Shangguan, S., . . . Kelman, J. A. (2024). Dispensing pharmacy chains and direct anticoagulants: Potential associations with patient outcomes. Pharmacoepidemiology and Drug Safety, 33(2), e5749.
25. Le, K. D. R., Le, K., & Foo, F. (2024). The Impact of Glucagon-like Peptide 1 Receptor Agonists on Obstructive Sleep Apnoea: A Scoping Review. Pharmacy, 12(1), 11.
26. Majd, Z., Mohan, A., Fatima, B., Johnson, M. L., Essien, E. J., & Abughosh, S. M. (2024). Trajectories of adherence to ACEI/ARB medications following a motivational interviewing intervention among Medicare Advantage beneficiaries in Texas. Patient Education and Counseling, 119, 108073.
27. Masad, S. M., Alshahrani, A. M., Alshubayni, A. M., Aldosar, A. M., Masad, M. M., & Ali, S. I. (2024). Evaluating medication adherence and its impact on glycemic control in elderly diabetic patients: a cross-sectional analysis. Pakistan Heart Journal, 57(1), 1-7.
28. Mellot, M., Jawal, L., Morel, T., Fournier, J.-P., Tubach, F., Cadwallader, J.-S., . . . Zerah, L. (2024). Barriers and Enablers for Deprescribing Glucose-Lowering Treatment in Older Adults: A Systematic Review. Journal of the American Medical Directors Association.
29. Mills, W. R., Howard, S., Pitzen, K., Smitherman, J., Cole, L., Wolfram, J., . . . Poltavski, D. (2024). A Novel Home-Based Medication Management Program and Its Influence on Hospitalization Rates among Home Health Care Recipients. Journal of the American Medical Directors Association, 25(1), 155-157. e151.
30. Mohajan, D., & Mohajan, H. K. (2024). Oral Hypoglycaemic Agents: Non-Insulin Medications for Type 2 Diabetes Patients. Innovation in Science and Technology, 3(1), 23-31.
31. Moon, J., Chladek, J. S., Wilson, P., & Chui, M. A. (2024). Clinical decision support systems in community pharmacies: a scoping review. Journal of the American Medical Informatics Association, 31(1), 231-239.
32. Neeland, I. J., Bourges-Sevenier, B., Dazard, J.-E., Albar, Z., Landskroner, Z., Tashtish, N., . . . Nennstiel, M. (2024). Second-year results from CINEMA: A novel, patient-centred, team-based intervention for patients with Type 2 diabetes or prediabetes at high cardiovascular risk. American Journal of Preventive Cardiology, 17, 100630.
33. Nyamagoud, S. B., Swamy, A. H. V., & Kangrali, B. (2024). Assessment of Health-Related Quality of Life and Associated Factors among Type 2 Diabetes Mellitus Patients Attending a Tertiary Care Hospital. Ind. J. Pharm. Edu. Res, 58(1), 326-332.
34. Oh, R. C., Murphy, K. C., Jenks, C. M., Lopez, K. B., Patel, C. M. A., Scotland, E. E., & Khanna, M. (2024). Low-Carbohydrate and Ketogenic Dietary Patterns for Type 2 Diabetes Management. Federal Practitioner, 41(1).
35. Othman, N., Lean, Q. Y., Neoh, C. F., Abd Wahab, M. S., Noor, N. M., Lim, S. L., & Wong, Y. Y. Trajectory, Perceived Causes and Efforts in Diabetes Self-management: A Qualitative Study Among Young People With Type 2 Diabetes Mellitus and Caregivers.
36. Parsons, K. A., Ekong, G. J., Charbonneau, M. S., Laisure, M. R., & Capoccia, K. L. (2024). Diabetes distress among people with type 2 diabetes in a pharmacist-run community care clinic. American Journal of Health-System Pharmacy, 81(1), e9-e11.
37. Ranganath, T., & Panda, P. S. (2024). ASSESSMENT OF DIABETIC LITERACY AND PERCEIVED GAPS IN HEALTHCARE PROVISION AMONG TYPE 2 DIABETES NEPHROPATHY PATIENTS: A MIXED METHOD STUDY IN A TERTIARY CARE CENTER IN BANGALORE. Int J Acad Med Pharm, 6(1), 310-314.
38. Sperl-Hillen, J. M., Haapala, J. L., Dehmer, S. P., Chumba, L. N., Ekstrom, H. L., Truitt, A. R., . . . Pankonin, M. A. (2024). Protocol of a patient randomised clinical trial to improve medication adherence in primary care. Contemporary Clinical Trials, 136, 107385.
39. Tokita, J., Lam, D., Vega, A., Wang, S., Amoruso, L., Muller, T., . . . Zabetian, A. (2024). A Real-World Precision Medicine Program Including the KidneyIntelX Test Effectively Changes Management Decisions and Outcomes for Patients With Early-Stage Diabetic Kidney Disease. Journal of Primary Care & Community Health, 15, 21501319231223437.
40. Torres-Novellas, B., Rius, P., Figueiredo-Escribá, C., Mariño, E. L., & Modamio, P. (2024). Drug-Related Problems Detected in Complex Chronic Patients by Community Pharmacists of Catalonia: Perception of the Person-Centred Approach Necessity. Paper presented at the Healthcare.
41. Zhang, R.-T., Liu, Y., Sun, C., Wu, Q.-Y., Guo, H., Wang, G.-M., . . . Bai, X.-Y. (2024). Predicting Hypoglycemia in Elderly Inpatients with Type 2 Diabetes: The ADOCHBIU Model.
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Jun 22, 2024
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How to Cite
Bander Alshehri, Wan Ahmad Syazani Mohamed, Usman Ali, Abdur Rehman, Muhammad Mohsin, Tariq Rafique, & Shabana Naz. (2024). ENHANCING DIABETES MELLITUS (DM2) CARE THROUGH PHARMACEUTICAL INTERVENTIONS: A REVIEW OF THE LITERATURE. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 1578-1588. https://doi.org/10.53555/jptcp.v31i6.6722
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Author Biographies
Bander Alshehri
Assistant Professor, Department of Medicine, University of Jeddah, Saudi Arabia
Wan Ahmad Syazani Mohamed
Medical Doctor, Nutrition Unit, Nutrition, Metabolism and Cardiovascular Research Centre (NMCRC), Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health Malaysia, Level 3, Block C7, No. 1, Jalan Setia Murni U13/52, Seksyen U13, Setia Alam, 40170 Shah Alam, Selangor, Malaysia
Usman Ali
Resident Physician, Department of Medicine, Ayub Teaching Hospital Abbottabad, Pakistan,
Abdur Rehman
Resident Physician, Department of General Medicine, Ayub Teaching Hospital Abbottabad, Pakistan
Muhammad Mohsin
Associate Editor, Research Journal of Innovative Ideas and Thoughts
Tariq Rafique
Assistant Professor Dadabhoy Institute of Higher Education, Karachi, Pakistan
Shabana Naz
Crop Reporting Service, Agriculture Department Sargodha, Government of Punjab, Pakistan
How to Cite
Bander Alshehri, Wan Ahmad Syazani Mohamed, Usman Ali, Abdur Rehman, Muhammad Mohsin, Tariq Rafique, & Shabana Naz. (2024). ENHANCING DIABETES MELLITUS (DM2) CARE THROUGH PHARMACEUTICAL INTERVENTIONS: A REVIEW OF THE LITERATURE. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 1578-1588. https://doi.org/10.53555/jptcp.v31i6.6722