TO COMPARE CERVIX RIPENING (USING MODIFIED BISHOP SCORE) BETWEEN PROSTIN E2 AND LAMINARIA + PROSTIN E2 IN WOMEN UNDERGOING INDUCTION OF LABOUR
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Keywords
Cervix ripening, Induction of labour, Laminaria, Modified bishop score, Prostin E2
Abstract
Objectives: To compare cervix ripening between laminaria+Prostin E2 and Prostin E2 alone in women undergoing induction of labour.
Study design: Randomized controlled trial.
Place and duration of study: This study was conducted at the MCH Center, Unіt-II, Pakistan Institute of Medical Sciences, Islamabad from 1st of November 2020 to 30th of April 2021. Methods: A total of 132 pregnant women with 37-42 weeks of gestation having singleton pregnancy and planned for induction of labour with unfavorable cervix (bishop score <5) were enrolled in this study and divided in 2 equal groups. In Group A, patients were inserted laminaria tents and intravaginal Prostin E2 3mg tablet (dinoprostone) while in-group B women only received intravaginal Prostin E2 3mg tablet. Primary outcome was set as improvement in modified bishop score and number of women where cervix ripening was achieved. The secondary outcomes were rate of spontaneous vaginal delivery, cesarean section and fetal wellbeing.
Results: The Mean±SD of age is this study was 27±4.6 years. The results of primary outcomes of study showed that women in Group A achieved significantly higher modified bishop score compared to women in Group B (8.9 ± 0.74 Vs 8.1+ 0.33, respectively, p=0.000). Similarly, cervix ripening was achieved in significantly more women in Group A compared to Group B (68.2% Vs 43.9% respectively, p=0.005). The results of secondary outcomes showed that significantly more women had spontaneous vaginal delivery, lesser needed caesarean section and neonates had significantly better APGAR score at 1 minute in Group A compared to Group B. Conclusions: The administration of laminaria along with Prostin E2 tablets results in higher modified bishop score indicating better cervix ripening than Prostin E2 tables alone in women undergoing induction of labour.
References
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Dr Hina Mushtaq
Post Graduate Resident Gynae & Obs, MCH Unit 2; PIMS Islamabad, Pakistan
Dr Sana Ghaffar Bajwa
Post Graduate Resident Gynae & Obs, MCH Unit 2; PIMS Islamabad, Pakistan
Dr Nida Arif
Post Graduate Resident Gynae & Obs, MCH Unit 2; PIMS Islamabad, Pakistan
Dr Sobia Haneef
Post Graduate Resident Pediatrics Medicine, Children Hospital; PIMS Islamabad, Pakistan
Dr Komal Tariq
Post Graduate Resident Cardiology, Ayub Teaching Hospital, Abbottabad, Pakistan
Dr Lubna Bibi
Post Graduate Resident Gyne & Obs, HMC Hospital, Peshawar, Pakistan