NANOPARTICLE-ENHANCED REGENERATIVE MEDICINE: A COMPREHENSIVE REVIEW ON APPLICATIONS, ADVANCES, AND DRUG DELIVERY SYSTEMS
Main Article Content
Keywords
Regenerative medicine, Nanoparticles, Tissue Engineering, drug delivery system
Abstract
Nanoparticle-enhanced regenerative therapies represent a paradigm shift in healthcare, using nanoparticles distinct capabilities to boost treatments for tissue repair and regeneration. The historical development, wide range of applications, and methodological complexities of nanoparticles integration in regenerative medicine are examined in this study. Through a thorough analysis of the literature, we are able to demonstrate the revolutionary potential of nanoparticles in enhancing regenerative processes, ranging from tissue engineering and targeted medication administration to imaging. Thematic studies highlight the adaptability and promise of nanoparticles in addressing medical needs by revealing applications across therapeutic modalities. An emphasis is placed on a rigorous approach that includes a thorough study design, selection criteria, and data analysis techniques to guarantee the integrity and dependability of the findings. The complex relationship between nanoparticles and regenerative processes is elucidated through findings and discussions, which also highlight significant turning points and the development of nanoparticle drug delivery systems as a pillar of regenerative medicine. This review concludes by summarizing the revolutionary field of nanoparticle-enhanced regenerative medicines and predicting a time when injured tissues would not only be mended but also effectively and precisely regenerated, bringing in a new era of individualized and regenerative healthcare.
References
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2. A. Bayes-Genis, P. Gastelurrutia, M.-L. Cámara, A. Teis, J. Lupón, C. Llibre, E. Zamora, X. Alomar, X. Ruyra, and S. Roura, "First-in-man safety and efficacy of the adipose graft transposition procedure (AGTP) in patients with a myocardial scar," EBioMedicine, vol. 7, pp. 248-254, 2016.
3. K. Chaudhury, V. Kumar, J. Kandasamy, and S. RoyChoudhury, "Regenerative nanomedicine: current perspectives and future directions," International Journal of Nanomedicine, pp. 4153-4167, 2014.
4. J. Bartunek, A. Terzic, B. A. Davison, G. S. Filippatos, S. Radovanovic, B. Beleslin, B. Merkely, P. Musialek, W. Wojakowski, and P. Andreka, "Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial," European heart journal, vol. 38, pp. 648-660, 2017.
5. M. Fathi-Achachelouei, H. Knopf-Marques, C. E. Ribeiro da Silva, J. Barthès, E. Bat, A. Tezcaner, and N. E. Vrana, "Use of nanoparticles in tissue engineering and regenerative medicine," Frontiers in bioengineering and biotechnology, vol. 7, p. 113, 2019.
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7. Q. Ullah, M. Qasim, A. Abaidullah, R. Afzal, A. Mahmood, A. Fatima, and I. Haidri, "EXPLORING THE INFLUENCE OF NANOPARTICLES AND PGPRS ON THE PHYSICO-CHEMICAL CHARACTERISTICS OF WHEAT PLANTS: A REVIEW," EPH-International Journal of Agriculture and Environmental Research, vol. 10, pp. 1-9, 2024.
8. L. Zhang and T. J. Webster, "Nanotechnology and nanomaterials: promises for improved tissue regeneration," Nano today, vol. 4, pp. 66-80, 2009.
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Jun 11, 2024
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Palwasha Tehseen, Umair Mahmood, Fatima Gulzar, Rabia Afzal, Aisha Ghaffar, Iqra Nawaz, Isma Rafiq, Mahpara Jabeen, Aqsa Abbas, & Rimsha Saleem. (2024). NANOPARTICLE-ENHANCED REGENERATIVE MEDICINE: A COMPREHENSIVE REVIEW ON APPLICATIONS, ADVANCES, AND DRUG DELIVERY SYSTEMS. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 929-954. https://doi.org/10.53555/jptcp.v31i6.6589
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Author Biographies
Palwasha Tehseen
Department of Chemistry, University of Agriculture Faisalabad, Pakistan
Umair Mahmood
Department of Biochemistry, University of Agriculture Faisalabad, Sub-Campus Toba Tek Singh, Pakistan
Fatima Gulzar
Department of Chemistry, University of Agriculture Faisalabad, Pakistan
Rabia Afzal
Department of Chemistry, University of Agriculture Faisalabad, Pakistan
Aisha Ghaffar
Department of Chemistry, University of Sialkot, Pakistan
Iqra Nawaz
Department of Chemistry, University of Sialkot, Pakistan
Isma Rafiq
Department of Chemistry, University of Sialkot, Pakistan
Mahpara Jabeen
Department of Chemistry, Government College University Faisalabad, Pakistan
Aqsa Abbas
Department of Chemistry, University of Agriculture Faisalabad, Pakistan
Rimsha Saleem
Department of Chemistry, University of Agriculture Faisalabad, Pakistan
How to Cite
Palwasha Tehseen, Umair Mahmood, Fatima Gulzar, Rabia Afzal, Aisha Ghaffar, Iqra Nawaz, Isma Rafiq, Mahpara Jabeen, Aqsa Abbas, & Rimsha Saleem. (2024). NANOPARTICLE-ENHANCED REGENERATIVE MEDICINE: A COMPREHENSIVE REVIEW ON APPLICATIONS, ADVANCES, AND DRUG DELIVERY SYSTEMS. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 929-954. https://doi.org/10.53555/jptcp.v31i6.6589