STUDY OF RECOVERY CHARACTERISTICS AND HEMODYNAMIC PARAMETERS AFTER USING SEVOFLURANE OR DESFLURANE IN SPINE SURGERIES

Main Article Content

Dr. Gauri S. Kene
Dr. Rachan Amin
Dr. Soujan Chowta
Dr. Yashvanth R.
Dr. Suchet Sharath
Dr. Akhil Rao U. K
Dr. Ramesh Prabhu

Keywords

Spine Surgery, Desflurane, Sevoflurane, Recovery Characteristics

Abstract

BACKGROUND: Spine surgeries are associated with intraoperative cardiovascular instability and there is significant intraoperative blood loss. Rapid recovery is desirable after a spine surgery as it enables early post-operative neurological evaluation and prompt management of complications. Inhaled anaesthetic agents like sevoflurane and desflurane have low blood gas partition coefficients and thus share the advantage of faster onset and neutralize of anesthetic effect as compared with older inhaled anaesthetic agents.


METHODS: The study was conducted in Lokmanya Tilak municipal medical college and general hospital, Mumbai. It is a randomized prospective study with 88 patients meeting inclusion criteria in all patients following parameters duration of surgery, level of spine surgery, hemodynamic parameters and recovery characteristics was recorded and evaluated.


RESULTS: We conclude that compared to sevoflurane, desflurane provides stable hemodynamic parameters and early recovery and emergence from anesthesia when in spine surgeries.


CONCLUSION: We conclude that desflurane provides stable hemodynamic parameters and early recovery and emergence from anesthesia compared to sevoflurane in spine surgeries.

Abstract 24 | PDF Downloads 29

References

[1] Gupta P, Rath GP, Prabhakar H, Bithal PK. Comparison between sevoflurane and desflurane on emergence and recovery characteristics of children undergoing surgery for spinal dysraphism. Indian J Anaesth 2015;59(8):482-7.
[2] Kaur A, Jain AK, Sehgal R, Sood J. Hemodynamics and early recovery characteristics of desflurane versus sevoflurane in bariatric surgery. J Anaesthesiol Clin Pharmacol 2013;29(1):36-40.
[3] Bastola P, Bhagat H, Wig J. Comparative evaluation of propofol, sevoflurane and desflurane for neuroanaesthesia: A prospective randomised study in patients undergoing elective supratentorial craniotomy. Indian J Anaesth 2015;59(5):287-94.
[4] Patil Y, Bagade S, Patil N, Jadhav N. A prospective randomized study comparing recovery following anesthesia with a combination of intravenous dexmedetomidine and desflurane or sevoflurane in spinal surgeries. J Anaesthesiol Clin Pharmacol 2017;33(4):524-8.
[5] Rodrigues G, Ravi C, Prabhu R. Fast-track surgery: a new concept of perioperative management of surgical patients. Journal of Health Specialties 2013;1(3):114.
[6] Chudasama, Palak A; Mehta, Milan V. Comparison of haemodynamic parameters and recovery characteristics between sevoflurane and desflurane in patients undergoing day-care surgical procedure. Advances in Human Biology 2018;8(3):140-4.
[7] Erk G, Erdogan G, Sahin F, Taspinar V, Dikmen B. Anesthesia for laparoscopic cholecystectomy: comparative evaluation--desflurane/sevoflurane vs. propofol. Middle East J Anaesthesiol 2007;19(3):553-62.
[8] Shan J, Sun L, Wang D, Li X. Comparison of the neuroprotective effects and recovery profiles of isoflurane, sevoflurane and desflurane as neurosurgical pre-conditioning on ischemia/reperfusion cerebral injury. Int J Clin Exp Pathol 2015;8(2):2001-9.
[9] Jindal R, Kumra VP, Narani KK, Sood J. Comparison of maintenance and emergence characteristics after desflurane or sevoflurane in outpatient anaesthesia. Indian J Anaesth 2011;55(1):36-42.
[10] Rörtgen D, Kloos J, Fries M, Grottke O, Rex S, Rossaint R, et al. Comparison of early cognitive function and recovery after desflurane or sevoflurane anaesthesia in the elderly: A double-blinded randomized controlled trial. Br J Anaesth 2010;104:167-74.
[11] White PF, Tang J, Wender RH, Yumul R, Stokes OJ, Sloninsky A, et al. Desflurane versus sevoflurane for maintenance of outpatient anesthesia: the effect on early versus late recovery and perioperative coughing 2009;109(2):387-93.
[12] Romeo RC, Bettencourt AB, Vallejo MC. Desflurane vs. sevoflurane wake up times in laparoscopic gastric patients. Anesthesiology 2004;101:A128.
[13] Vallejo MC, Sah N, Phelps AL, O'Donnell J, Romeo RC. Desflurane versus sevoflurane for laparoscopic gastroplasty in morbidly obese patients. J Clin Anesth. 2007;19(1):3-8.
[14] Magni G, Rosa IL, Melillo G, Savio A, Rosa G. A comparison between sevoflurane and desflurane anesthesia in patients undergoing craniotomy for supratentorial intracranial surgery. Anesth Analg 2009;109(2):567-71.
[15] Macario A, Dexter F, Lubarsky D. Meta-analysis of trials comparing postoperative recovery after anesthesia with sevoflurane or desflurane. Am J Health Syst Pharm 2005;62(1):63-8.