The Efficacy of Pentazocine and Diclofenac Versus Paracetamol and Diclofenac for Post- Caesarean Section Analgesia
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Keywords
Nonsteroidal anti-inflammatory drugs (NSAIDs), Pentazocine, Diclofenac, Paracetamol, Post- Caesarean.
Abstract
It is well acknowledged that a kind of multimodal analgesia may be achieved by combining parenteral opioid-like pentazocine or tramadol with nonsteroidal anti-inflammatory drugs (NSAIDs) as diclofenac. This combination offers the advantages of both pain reduction and additive anti-inflammatory activities.
Aim: To assess the effectiveness of diclofenac and pentazocine vs diclofenac and paracetamol for post-operative pain management after cesarean delivery.
Patients and methods: Five papers were examined after an automated search of Medline, PubMed, the Cochrane Library, Scopus, Science Direct, and Google Scholar. Research that look at the effectiveness of diclofenac and pentazocine for post-csection analgesia in comparison to diclofenac and paracetamol. quasi-randomized controlled trials or randomized controlled trials (RCTs). Studies conducted on human participants. Studies available in English language. Studies with interventions using pentazocine and diclofenac in one arm and paracetamol and diclofenac in another arm, with appropriate dosages and administration routes.
Results: Our findings showed that As in the included studies, the individuals' mean age was 29.8 ± 5.9 years, with a range of 20 to 34 years. five studies were discussed.
Conclusion: We concluded that Both analgesic combos might be sufficient to relieve pain within the first 24 hours after surgery. In the first 24 hours after CS, pentazocine and diclofenac produced greater analgesia than paracetamol and diclofenac, but they were also more likely to cause adverse effects.
References
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