DOMPERIDONE INDUCED GALACTORRHOEA IN REPRODUCTIVE AGE GROUP FEMALES- A CASE SERIES
Main Article Content
Keywords
Domperidone, drug induced galactorrhoea, galactorrhoea, prolactin, reproductive age group females.
Abstract
Background: Domperidone is a commonly utilized anti-emetic and combination drug with proton pump inhibitor. Galactorrhoea is a exceptional adverse effect of this drug.
Aim: To report the rare side effect of domperidone i.e. galactorrhoea.
Method: A hospital based case study of females taking domperidone presenting with galactorrhoea.
Result: The females of reproductive age group on domperidone showed galactorrhoea as an uncommon side effect.
Conclusion: Females displaying with galactorrhoea ought to be explored for prolactenemia and appropriate history of intake Domperidone.
References
1. Barone JA. Domperidone: a peripherally acting dopamine2-receptor antagonist. Ann Pharmacother. 1999;33:429–440. [PubMed] [Google Scholar] [Ref list]
2. Reddymasu SC, Soykan I, McCallum RW Domperidone: review of pharmacology and clinical applications in gastroenterology..Am J Gastroenterol. 2007 Sep;102(9):2036-45. doi: 10.1111/j.1572-0241.2007.01255.x. Epub 2007 May 3.PMID: 17488253 Review
3. Melmed JS, Jameson L. Disorders of Anterior Pituitary and Hypothalamus. In: Fauci AS (editor). Harrison’s Principles of Internal Medicine. 7th edition. New York: McGraw-Hill Co. 2008;2205-6.3.Cann PA, Read NW, Hold
4. Cann PA, Read NW, Holdsworth CD. Galactorrhoea as side effect of domperidone. Br Med J (Clin Res Ed) 1983;286:1395–6. [PMC free article] [PubMed] [Google Scholar]
5. Domperidone induced galactorrhea: An unusual presentation of a common drug Mary Anne Poovathingal, Rama Bhat, and Ramamoorthi. Indian J Pharmacol. 2013 May-Jun; 45(3): 307–308.doi: 10.4103/0253-7613.111913
6. Shlomo Melmed J, Larry Jameson. Disorders of Anterior Pituitaryand Hypothalamus. In: Fauci AS et al. Harrison’s Principles ofInternal Medicine. XVIIth editon, Vol II, New York: McGraw-Hill Co.2008; 2205-6.
2. Reddymasu SC, Soykan I, McCallum RW Domperidone: review of pharmacology and clinical applications in gastroenterology..Am J Gastroenterol. 2007 Sep;102(9):2036-45. doi: 10.1111/j.1572-0241.2007.01255.x. Epub 2007 May 3.PMID: 17488253 Review
3. Melmed JS, Jameson L. Disorders of Anterior Pituitary and Hypothalamus. In: Fauci AS (editor). Harrison’s Principles of Internal Medicine. 7th edition. New York: McGraw-Hill Co. 2008;2205-6.3.Cann PA, Read NW, Hold
4. Cann PA, Read NW, Holdsworth CD. Galactorrhoea as side effect of domperidone. Br Med J (Clin Res Ed) 1983;286:1395–6. [PMC free article] [PubMed] [Google Scholar]
5. Domperidone induced galactorrhea: An unusual presentation of a common drug Mary Anne Poovathingal, Rama Bhat, and Ramamoorthi. Indian J Pharmacol. 2013 May-Jun; 45(3): 307–308.doi: 10.4103/0253-7613.111913
6. Shlomo Melmed J, Larry Jameson. Disorders of Anterior Pituitaryand Hypothalamus. In: Fauci AS et al. Harrison’s Principles ofInternal Medicine. XVIIth editon, Vol II, New York: McGraw-Hill Co.2008; 2205-6.