FREQUENCY OF NEUROPSYCHIATRIC ILLNESS OF PSORIASIS

Main Article Content

Zohra Samreen
Sara Inayat Khan
Sundus Jahangir
Beenish Mahjabeen
Bakhtawar Urooj
Bushra Nazish
Muhammad Kamran Taj
Saad Rehman

Keywords

Neuropsychiatric, Illness, Psoriasis, Psychosocial, Morbidity

Abstract

Objective:


To determine the frequency of different neuropsychiatric illnesses in patients of psoriasis.


Material and Methods:


Psoriasis and psychological disturbances are linked together like other mental disorders, particularly depression and anxiety. The psoriasis patients (n=48) visiting the dermatology outpatient department of a tertiary care hospital, Quetta over a year were selected for the study.


Result:


 Plaque psoriasis (n=33; 68.7%) was the most common type of psoriasis among the participants, followed by palmoplantar psoriasis (n=7; 14.4%), erythrodermic psoriasis (n=5; 10.4%) and guttate (n=3; 6%) psoriasis. Males (n=31; 64.58%) were more likely to be affected by psoriasis than females (n=17; 35.41%). Psychiatric screeners were positive in 62.5% of patients in the study and negative in 37.5%. The results showed that 21 (63.6%) of the plaque psoriasis individuals had positive results, while palmoplantar (n=3; 42.8%) and erythrodermic (n=3; 60%) had the lowest psychiatric morbidity. The guttate had the highest prevalence of psychiatric screener positivity (n=3; 100%). According to the skindex, the commonest psychiatric morbidity in psoriasis patients was fear (68.75%), followed by embarrassment (66.66%), depression (64.58%), anger (62.5%), social problem (60.41%), discomfort (58.33%), cognitive impairment (47.91%) and physical limitation (41.66%).


Conclusion:
The study highlights plaque psoriasis as the most prevalent type, with males more affected than females. Psychiatric screeners revealed substantial positivity, particularly in guttate psoriasis. Skindex analysis showcased prevalent psychological morbidities, notably fear and embarrassment. This underscores the need for holistic management, recognizing the profound impact of psoriasis on mental well-being alongside dermatological symptoms. Integrating psychiatric care into treatment strategies is vital for improving the quality of life for patients grappling with the psychosocial burdens of psoriasis.

Abstract 230 | pdf Downloads 132

References

Akay, A.Y.N.U.R., Pekcanlar, A., Bozdag, K.E., Altintas, L. & Karaman, A. (2002). Assessment of depression in subjects with psoriasis vulgaris and lichen planus. Journal of the European Academy of Dermatology and Venereology, 16(4), 347-352.
2. American Psychiatric Association, D.S.M.T.F. and American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM-5 (Vol. 5, No. 5). Washington, DC: American psychiatric association.
3. Barankin, B. & DeKoven, J. (2002). Psychosocial effect of common skin diseases. Canadian Family Physician, 48(4), 712-716.
4. Langley, R.G.B., Krueger, G.G. & Griffiths, C. (2005). Psoriasis: epidemiology, clinical features, and quality of life. Annals of the Rheumatic Diseases, 64(suppl 2), ii18-ii23.
5. Basavaraj, K.H., Navya, M.A. & Rashmi, R. (2011). Stress and quality of life in psoriasis: an update. International Journal of Dermatology, 50(7), 783-792.
6. Bharath, S., Shamasundar, C., Raghuram, R. & Subbakrishna, D.K. (1997). Psychiatric morbidity in leprosy and psoriasis--a comparative study. Indian Journal of Leprosy, 69(4), 341-346.
7. Boehncke, W.H. & Boehncke, S. (2014). More than skin-deep: the many dimensions of the psoriatic disease. Swiss Medical Weekly, 144(1718), w13968-w13968.
8. Burkauskas, J., Slabadiene, M., Podlipskyte, A. & Steibliene, V. (2023). Factors associated with worsened clinical symptoms of psoriasis and disease-related quality of life during the COVID-19 lockdown: A cross-sectional study. Frontiers in Medicine, 9, 1027853.
9. Chen, Y. & Lyga, J. (2014). Brain-skin connection: stress, inflammation and skin aging. Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets-Inflammation & Allergy)(Discontinued), 13(3), 177-190.
10. Dediol, I., Buljan, M., Buljan, D., Bulat, V., Vurnek Živković, M. & Situm, M. (2009). Association of psoriasis and alcoholism: psychodermatological issue. Psychiatria Danubina, 21(1), 9-13.
11. Ferreira, B.I.R.C., Abreu, J.L.P.D.C., Dos Reis, J.P.G. & Figueiredo, A.M.D.C. (2016). Psoriasis and associated psychiatric disorders: a systematic review on etiopathogenesis and clinical correlation. The Journal of Clinical and Aesthetic Dermatology, 9(6), 36.
12. Gaikwad, R., Deshpande, S., Raje, S., Dhamdhere, D.V. & Ghate, M.R. (2006). Evaluation of functional impairment in psoriasis. Indian Journal of Dermatology, Venereology and Leprology, 72, 37.
13. Han, C., Lofland, J.H., Zhao, N. & Schenkel, B. (2011). Increased prevalence of psychiatric disorders and health care-associated costs among patients with moderate-to-severe psoriasis. Journal of Drugs in Dermatology: JDD, 10(8), 843-850.
14 Paraskevi, M., Corinna, M., Gabriele, G., Stephan, H. & Georg, J. (2020). Skin diseases in patients with primary psychiatric disorders. Psychiatry Investigation, 17(2): 157–162.
15. Joy, W., Sonia, W., Daniel, B., Shin, M.N., Syed, K.A., Adina, R.L. & Joel M.G. (2023). Neuropsychiatric disorders in adults with atopic dermatitis: A population-based cohort study. Journal of the European Academy of Dermatology and \Venereology, 38(3): 543-548.
16. Charlotte, R. & Armstrong, W. (2020). Association between the mental health of patients with psoriasis and their satisfaction with physicians. JAMA Dermatology, 156(7):754-76
17. Jing, J. (2021). Psychiatric morbidity in patients with psoriasis, acne, vitiligo and other dermatological disorders. Ethiopian Journal of Health Development, 35(3): 35(3): 264-269.
18. Sarkar, S., Sarkar, A., Saha, R. & Sarkar, T. (2014). Psoriasis and psychiatric morbidity: a profile from a tertiary care centre of Eastern India. Journal of family Medicine and Primary Care, 3(1), 29.
19. Chag, J., Javadekar, A., Mukherjee, S.S., Chaudhury, S & Saldanha, D. (2022). Psychiatric Co-Morbidy and quality of life in patients with psoriasis in a tertiary care hospital. The Journal of International Medical Sciences Academy, 35($):337-343.

Most read articles by the same author(s)