INCIDENCE OF NON-INVASIVE VENTILATION FAILURE AND MORTALITY IN CHILDREN WITH ACUTE RESPIRATORY DISTRESS SYNDROME

Main Article Content

Dr Aamir Shehzad
Dr Osama Omer
Dr Arham Mahmood
Ikram Ullah Khan
Ihsan Ullah Khan
Dr Rabia Tabassum
Zara Haseen
Dr. Hooria Ahmad

Keywords

Abstract

Introduction: Acute respiratory distress syndrome (ARDS) poses a significant challenge in pediatric care due to its potential for respiratory failure and mortality.


Objectives: The main objective of the study is to find the incidence of non-invasive ventilation failure and mortality in children with acute respiratory distress syndrome.


Material and methods: This retrospective study was conducted at Lady Reading Hospital Peshawar from August 2020-August 2021. Data was collected from 220 patients suffering from ARDS.Patients meeting the inclusion criteria were identified, and their demographic information, clinical characteristics, and management details were extracted. Relevant data points included age, gender, comorbidities, etiology of ARDS, severity of illness scores, Pediatric Index of Mortality 2 - PIM2, oxygenation parameters, initiation and duration of non-invasive ventilation (NIV), complications during NIV therapy, outcomes and length of PICU stay.


Results: Data were collected from 220 patients from both genders suffering from ARDS. In the NIV success group, the mean age was 7.5± 2.1 years compared to 8.3± 2.5 years in the NIV failure group. The mean weight was slightly lower in the success group (24.5 kg ± 4.2) compared to the failure group (25.1 kg ± 4.5). Regarding ARDS severity, the majority of patients in both groups had moderate ARDS, with 46.2% and 44.4% in the success and failure groups, respectively. Among patients with mild ARDS, 10% experienced NIV failure, while in the moderate group, the failure rate increased to 25%. Significantly, patients with severe ARDS had the highest NIV failure rate at 40%.


Conclusion: It is concluded that non-invasive ventilation (NIV) failure rates differ significantly among children with acute respiratory distress syndrome (ARDS), with higher rates observed in severe ARDS cases.

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