LEVEL OF VITAMIN B12 IN IRON DEFICIENCY ANEMIA STUDY FROM LARKANA, PAKISTAN

Main Article Content

Ishfaque Ahmed Mugheri
Mehar Ali Kazi
Ali Muhammad Shahani
Zoya
Mahwish
Dr Beenish Ghafar Memon

Keywords

iron deficiency anemia, vitamin B12-deficiency anemia

Abstract

Introduction: According to most research, anemia affects 10% to 45% of the elderly. The etiology is often complex and diverse.


Aim: This study aims to evaluate the level of vitamin B12 in iron deficiency anemia in elderly residents of the Larkana region.


Materials and Methods: A total of 280 people were included from which 140 were IDA Patients and 140 were control male and female both were included in this study with a mean age of 26.23 years. Blood Sample was collected for Complete blood count and vitamin B12 level. Only Larkana region participants were included in this study


Results: 50.71% of 280 were reported with low levels of vitamin B12 with confirmed IDA from which 46 (32.85%) females were reported with a low level of vitamin B12 and 25 (17.85) male was reported with a low level of vitamin B12 level who were confirmed IDA Patients. The mean level of B12 in patients was 230.9±46.23 with a P-value of 0.003.


Conclusion: Vitamin B12 level was low in iron deficiency anemia patients. It was more reported low level in females as compared to males.

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References

1. Johnson-Wimbley, T. D., Graham, D. Y. Diagnosis and management of iron deficiency anemia in the 21st century. Therap Adv Gastroenterol. 2011;4(3):177-184.
2. Balasubramaniyam, K., Balakrishnan, G., Thalenjeri, P., Rao, V. A descriptive study of myriad risk factors in anemia of varied severity among reproductive female patients visiting a tertiary care setup in coastal Karnataka. Biomedicine. 2023; 43(02):706-712.
3. Allali, S., Brousse, V., Sacri, A. S., Chalumeau, M., de Montalembert, M. Anemia in children: prevalence, causes, diagnostic work-up, and long-term consequences. Expert Rev Hematol. 2017;10(11):1023-1028.
4. Walter, T. Effect of iron-deficiency anemia on cognitive skills and neuromaturation in infancy and childhood. Food Nutr Bull. 2003;24(4 Suppl): S104-S110.
5. Lukowski, A.F., Koss, M., Burden, M.J., Jonides, J., Nelson, C.A., Kaciroti, N., et al., Iron deficiency in infancy and neurocognitive functioning at 19 years: evidence of long-term deficits in executive function and recognition memory. Nutr Neurosci. 2010;13(2):54-70.
6. D. Rajkumar, Dineshkumar, J., Arunprasath, T. S. Anaemia in infants and young children- Risk factor analysis: Case control study. Biomedicine. 2022;42(1):169-172.
7. Guralnik, J. M., Eisenstaedt, R. S., Ferrucci, L., Klein, H. G, Woodman, R. C. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;104:2263-2268.
8. Stauder, R., Valent, P., Theurl, I. Anemia at older age: Etiologies, clinical implications, and management. Blood. 2018;131:505-514.
9. Bhasin, A., Rao, M.Y. Characteristics of anemia in elderly: A hospital based study in South India. Indian J Hematol Blood Transfus. 2011;27:26-32.
10. Sharma, D., Suri, V., Pannu, A.K., Attri, S.V., Varma, N., Kochhar, R., et al., Patterns of geriatric anemia: A hospital based observational study in North India. J Family Med Prim Care. 2019;8:976-980.
11. Bisht, N., Sofia, N. S. Prevalence and pattern of anemia in elderly A hospital based study. Int J Curr Res Med Sci. 2017; 3:27-35.
12. Juárez-Cedillo, T., Basurto-Acevedo, L., Vega-García, S., Manuel-Apolinar. L., Cruz-Tesoro, E., Rodríguez-Pérez, J. M., et al., Prevalence of anemia and its impact on the state of frailty in elderly people living in the community: SADEM study. Ann Hematol. 2014; 93(12): 2057-2062.
13. Le, C. H. The prevalence of anemia and moderate-severe anemia in the US population (NHANES 2003-2012). PloS one. 2016;11(11):e0166635.
14. Zakai, N. A., McClure, L. A., Prineas, R., Howard, G., McClellan, W., Holmes, C. E., et al., Correlates of anemia in American blacks and whites: the REGARDS renal ancillary study. Am J Epidemiol. 2009;169(3): 355-364.
15. Gaskell, H., Derry, S., Moore, R., McQuay, H. Prevalence of anaemia in older persons: systematic review. BMC. Geriatrics. 2008;8:1-7.
16. 13. Janus J, Moerschel SK. Evaluation of anemia in children. Am Fam Physician 2010 15;81(12):1462-71.
17. 14. Lanzkowsky P. Classification and Diagnosis of Anemia During Childhood. In: Lanzkowsky P. Manual of Pediatric Hematology and Oncology. 4th Ed. Elsevier Press, USA, 2005, pp. 4.
18. 15. Worldwide prevelance of anemia 1993 - 2005- WHO Global Database on Anemia. Editors: Bruno de Benoist, Erin McLean, Ines Egli, Mary Cogswell. Publication date: 2008 ISBN: 978 92 4 15966 7.

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