AEFI (ADVERSE EVENTS FOLLOWING IMMUNIZATION) AMONG CHILDREN LESS THAN 2 YEARS FOLLOWING PENTAVALENT VACCINE– A CROSS-SECTIONAL STUDY IN INDIA

Main Article Content

Pragya Dixit MD
Praveen Prashant MD
Vivek Gera MD
Abhishek Bansal MSc

Keywords

Vaccination, Immunization, Adverse Events Following Immunization, pentavalent vaccine, AEFI

Abstract

Introduction: Despite significant progress in vaccine-preventable disease control, Immunization is not free of controversies. Vaccine safety is increasingly becoming important because of alleged safety issues that can derail vaccine programs worldwide.


Aims: To study AEFI (Adverse Events Following Immunization) following the Pentavalent vaccine among children under two years old getting immunized at the session site.


Methods and Material: The study was a population-based cross-sectional study. A total of 209 children got vaccinated at the selected sub-centers for one year. The investigator contacted the mothers of the vaccinated children through two home visits. A pre-designed, pre-tested, semi-structured schedule was used to gather data. Categorical data was presented as a percentage (%). The descriptive analysis of data was depicted in graphs and percentages after statistical analysis.


Results: It was observed that AEFI incidence rate per 1000 doses was higher following the first dose of pentavalent vaccine (312.05), followed by the second dose (290.78) and third dose (271.42), fever [31.3% (1st dose), 29.1% (2nd dose), 27.1% (3rd dose)] was the most common AEFI observed. All the mothers (100%) were told that the vaccine was responsible for the occurrence of AEFI in their children and wished to continue vaccinating their children for further doses.


Conclusion: All the AEFI observed were minor. The benefits of vaccines outweighed the AEFI observed, as the mothers were willing to continue vaccinating their children even after the occurrence of AEFI.

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