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Pragya Dixit MD
Praveen Prashant MD
Vivek Gera MD
Abhishek Bansal MSc


Vaccination, Immunization, Adverse Events Following Immunization, pentavalent vaccine, AEFI


Introduction: Despite significant progress in vaccine-preventable disease control, Immunization is not free of controversies. Vaccine safety is increasingly becoming important because of alleged safety issues that can derail vaccine programs worldwide.

Aims: To study AEFI (Adverse Events Following Immunization) following the Pentavalent vaccine among children under two years old getting immunized at the session site.

Methods and Material: The study was a population-based cross-sectional study. A total of 209 children got vaccinated at the selected sub-centers for one year. The investigator contacted the mothers of the vaccinated children through two home visits. A pre-designed, pre-tested, semi-structured schedule was used to gather data. Categorical data was presented as a percentage (%). The descriptive analysis of data was depicted in graphs and percentages after statistical analysis.

Results: It was observed that AEFI incidence rate per 1000 doses was higher following the first dose of pentavalent vaccine (312.05), followed by the second dose (290.78) and third dose (271.42), fever [31.3% (1st dose), 29.1% (2nd dose), 27.1% (3rd dose)] was the most common AEFI observed. All the mothers (100%) were told that the vaccine was responsible for the occurrence of AEFI in their children and wished to continue vaccinating their children for further doses.

Conclusion: All the AEFI observed were minor. The benefits of vaccines outweighed the AEFI observed, as the mothers were willing to continue vaccinating their children even after the occurrence of AEFI.

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