THE SCIENCE OF HOPE: A COMPREHENSIVE REVIEW OF COVID-19 VACCINE PROGRESS

Main Article Content

Ashish Srivastava
Versha Chaturvedi
Pranay Wal
Parul Srivastava
Ankita Wal
Anil Yadav

Keywords

SARS-CoV-2, COVID-19, coronavirus, vaccine

Abstract

It is expected that the SARS-CoV-2 (severe acute respiratory syndrome-CoV-2) virus started a pandemic in 2020 that had affected the health of people everywhere in the world. Scientists are still trying to find COVID-19 vaccines and medicines that work. In this review article the study on the COVID-19 candidates for the vaccine that are currently going through clinical trials, in addition to the top candidates that are going through pre-clinical development and research at the moment. Five main bases were used to make these candidates There is a live-attenuated vaccine, an mRNA-based vaccine, DNA vaccines, an inactivated virus, and a viral-vector-based vaccine. Making a fast vaccine against other coronaviruses like SARS-CoV and MERS-CoV are similar to SARS-CoV-2 is dangerous for many reasons. The most important things that need to be done quickly are finding out how dangerous a new virus is and if it might have an antigen, choosing the best experimental models and delivery methods for the vaccine, doing the immune response study, setting up the clinical trials, and figuring out if the vaccine is safe and effective.

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