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Muhammad Amjad Hussain
Muhammad Sajid
Sana Hafeez
Muhammad Sarfraz
Rida Rashid
Asia Riaz
Muhammad Tahir


colorectal cancer, gender, age, lifestyle, colonoscopy


Background: In the rapidly evolving landscape of education, the integration of technology has become pivotal for fostering effective learning environments. This study investigates the impact of adaptive learning platforms on educational outcomes, with a focus on secondary school settings. The increasing prevalence of digital tools in classrooms necessitates a comprehensive understanding of their influence on student performance and engagement.

Objective: The objective of this study was to relations of colorectal cancer with gender, age and lifestyle difference over age 45 years screened by colonoscopy in Lahore from 2022-2023.

Method: The study investigated colorectal cancer patterns at Shalamar Hospital's Oncology Department using a retrospective cohort design with a sample size of 40 individuals aged 45 and above who underwent colonoscopy screenings during the study period. Shalamar Hospital in Lahore served as the setting for this research. Inclusion criteria encompassed age and colonoscopy screenings at the Oncology Department, while exclusion criteria involved patients under 45 and those with a history of colorectal cancer. Data collectors, trained to maintain privacy, extracted information from available records, focusing on age, gender, colonoscopy findings, colorectal cancer diagnosis, and lifestyle factors. Descriptive statistics summarized the data, and inferential statistics assessed associations between colorectal cancer and gender, age, and lifestyle. Ethical considerations and patient privacy were prioritized throughout the study. The findings aimed to contribute insights into colorectal cancer trends at Shalamar Hospital, guiding potential tailored screening and prevention strategies.

Results: The correlations between colorectal cancer and various factors are presented in Table 3. The risk associated with being male and obesity were significantly higher. Age played a critical role, with the highest risk observed in the 45-54 age group. In contrast, regular physical activity and being female showed a lower association with colorectal cancer risk. Dietary habits, specifically high consumption of red/processed meat, and high intake of fruits/vegetables, were also significant factors. Smoking emerged as the factor with the highest odds ratio, underscoring its substantial impact on colorectal cancer risk.

Conclusion: The research findings have substantial implications for the proposed strategies aimed at preventing and screening colorectal cancer. The increased prevalence of colorectal cancer among those with a familial predisposition to the disease, a medical history of gastrointestinal disorders, or the presence of polyps emphasizes the need for early detection and targeted screening protocols in these at-risk groups. The correlation between lifestyle factors such as smoking, dietary habits, and obesity and the heightened susceptibility to colorectal cancer underscores the need for public health interventions that promote modifications in lifestyle. Moreover, the limited understanding of the hazards and indications of colorectal cancer underscores the imperative need for educational campaigns that advocate for timely screening and disseminate information. In summary, the results of this study suggest that a comprehensive approach is necessary to combat colorectal cancer. This approach aims to reduce the incidence of this widespread disease and enhance the welfare of those afflicted by integrating customized medical interventions with broader public health initiatives.

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3. Parikh D, Mittal M, Al-Juburi A, Garcia J, Sacramento C. The Dynamic Global Incidence of Acute Appendicitis: A Systematic Review of International Temporal Trends. 2010.
4. Chin CC, Kuo YH, Yeh CY, Chen JS, Tang R, Changchien CR, et al. Role of body mass index in colon cancer patients in Taiwan. World journal of gastroenterology. 2012;18(31):4191-8.
5. Skotnicki A, Lissitchkov TJ, Mamonov V, Buevich E, Kuliczkowski K, Goranov S, et al. Efficasy, safety, and pharmacokinetics results of a phase II, double-blinded, randomized, cross-over study with Biostate in subjects with hemophilia A (the SWIFT-HA Study). Haemophilia (2012) 18 (Suppl 3) 1-208. 2012.
6. Smith MH. Cancer and Epidemiology literature. breast cancer. 2012;10(6):492-7.
7. Bardou M, Barkun AN, Martel M. Obesity and colorectal cancer. Gut. 2013;62(6):933-47.
8. Robsahm TE, Aagnes B, Hjartåker A, Langseth H, Bray FI, Larsen IK. Body mass index, physical activity, and colorectal cancer by anatomical subsites: a systematic review and meta-analysis of cohort studies. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 2013;22(6):492-505.
9. Sinicrope FA, Foster NR, Yothers G, Benson A, Seitz JF, Labianca R, et al. Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy. Cancer. 2013;119(8):1528-36.
10. Anker A, Welponer T, Judeeba S, Geibel J, Nadeem M, Observer NA, et al. 2015 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Nashville, Tennessee, USA, 15–18 April 2015. Surg Endosc. 2015;29:S410-S547.
11. Organization WH. Index medicus for the WHO Eastern Mediterranean Region: with abstract: IMEMR current content. 2015.
12. Adachi T, Hinoi T, Kinugawa Y, Enomoto T, Maruyama S, Hirose H, et al. Lower body mass index predicts worse cancer-specific prognosis in octogenarians with colorectal cancer. Journal of gastroenterology. 2016;51(8):779-87.
13. Crawford J. Colorectal Cancer Screening Behaviours of South Asian Immigrants in Canada: An Exploratory Mixed Methods Study: University of Toronto (Canada); 2016.
14. Crawford J, Ahmad F, Beaton D, Bierman AS. Cancer screening behaviours among S outh A sian immigrants in the UK, US and C anada: a scoping study. Health & social care in the community. 2016;24(2):123-53.
15. Hanyuda A, Ogino S, Qian ZR, Nishihara R, Song M, Mima K, et al. Body mass index and risk of colorectal cancer according to tumor lymphocytic infiltrate. International journal of cancer. 2016;139(4):854-68.
16. Bell S, Kong JC, Wale R, Staples M, Oliva K, Wilkins S, et al. The effect of increasing body mass index on laparoscopic surgery for colon and rectal cancer. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2018;20(9):778-88.
17. Meijers WC, Maglione M, Bakker SJL, Oberhuber R, Kieneker LM, de Jong S, et al. Heart Failure Stimulates Tumor Growth by Circulating Factors. Circulation. 2018;138(7):678-91.
18. Van Blarigan EL, Fuchs CS, Niedzwiecki D, Zhang S, Saltz LB, Mayer RJ, et al. Association of Survival With Adherence to the American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors After Colon Cancer Diagnosis: The CALGB 89803/Alliance Trial. JAMA oncology. 2018;4(6):783-90.
19. Auyeung AB, Ma W, Gallant R, Wang Y, Ni H, editors. Conference for Healthcare and Medical Students (ICHAMS). BMC Proceedings; 2020.
20. Lee DW, Cho S, Shin A, Han SW, Kim TY. Body mass index and body weight change during adjuvant chemotherapy in colon cancer patients: results from the AVANT trial. Sci Rep. 2020;10(1):19467.
21. ElFar OA, Billa N, Lim HR, Chew KW, Cheah WY, Munawaroh HSH, et al. Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes. Bioengineered. 2022;13(6):14681-718.
22. Fuchs J, Schellerer VS, Brunner M, Geppert CI, Grützmann R, Weber K, et al. The impact of body mass index on prognosis in patients with colon carcinoma. International journal of colorectal disease. 2022;37(5):1107-17.
23. Galy O, Markofski MM, Lopez-Bueno R, Choi S-W, Oh S, Chun S, et al. Vitamin D and Exercise Are Major Determinants of Natural Killer Cell Activity, Which Is Age-and Gender-Specific. Modern Lifestyle and Health: How Changes in the Environment Impacts Immune Function and Physiology. 2022.
24. Haji Sarbini HNA. A Study on Work-Life Balance and'Maternal Bodies' Post-Maternity Leave in Brunei: University of York; 2022.
25. Padron-Monedero A, Collaborators GCC. Global, regional, and national burden of colorectal cancer and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. 2022.
26. Saleem S, Aleem I, Zeshan M, Bakar MA, Atiq A, Tahseen M, et al. Body Mass Index and Other Risk Factors Effects on Colon Cancer Prognosis in Pakistan. Journal of Cancer & Allied Specialties. 2022;8(2).
27. Basile D, Rosati G, Bergamo F, Garattini SK, Banzi M, Zampino M, et al. Prognostic Value of Body Mass Index in Stage II/III Colon Cancer: Posthoc Analysis From the TOSCA Trial. Clinical colorectal cancer. 2023;22(2):190-8.
28. Ferrari E, Vecchi E, Mattei G, Belloli G, Diegoli G, Monte P, et al. The shape of water-preliminary data from a cluster of patients infected by Mycobacterium saskatchewanense in Haemodialysis setting in Emilia-Romagna, Northern Italy. Population Medicine. 2023; 5(Supplement).
29. Gallois C, Shi Q, Meyers JP, Iveson T, Alberts SR, de Gramont A, et al. Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023;41(4):803-15.
30. Khamjan NA, Ahmed FA, Madkhali NM, Ayyoub LA, Dighriri RY, Kariri KA, et al. Evaluation of the Knowledge of the Most Common Cancers Among Health Students at Jazan University, Saudi Arabia: A Cross-Sectional Study. Cureus. 2023;15(9).
31. Lopes S, Sousa ABd, Cohen JC, Gomes B. How were place of death trends for cancer patients affected by the COVID-19 pandemic? An international death certificate study. Population Medicine. 2023;5(Special Issue Supplement/2023):A413.
32. Mangili S, Ferraguzzi G, Capolongo S. Assessing the quality of the built environment in dementia: a framework to evaluate long-term care facilities. Population Medicine. 2023;5(Supplement):55-.
33. Maqbool M, Khan A, Shahzad A, Sarfraz Z, Sarfraz A, Aftab H, et al. Predictive biomarkers for colorectal cancer: a state-of-the-art systematic review. Biomarkers. 2023;28(6):562-98.
34. Murad MA, Sagga AK, Sagga BK, Anwer F, Malik HN, Hameed S, et al. Assessing Awareness and Utilization of Preventive Services, Complications, and Risk Factors Among Diabetic Patients in Jeddah, Saudi Arabia: Preventive Services among Diabetic Patients. Pakistan Journal of Health Sciences. 2023:124-9.
35. Riccio M, Greco S, Profeta V, Lorini C, Persiani N, Remigis S, et al. The integrated pathways of care in the social and healthcare services: the AgICOT experience in Teramo, Italy. Population Medicine. 2023;5:53-.
36. Sultan H, Khan UA, Riaz S. The Impact Of Psychosocial Factors On Medication Adherence Among Ulcerative Colitis Patients In Lahore, Pakistan. Journal of Positive School Psychology. 2023:858-69.
37. Vilsan J, Maddineni SA, Ahsan N, Mathew M, Chilakuri N, Yadav N, et al. Open, Laparoscopic, and Robotic Approaches to Treat Colorectal Cancer: A Comprehensive Review of Literature. Cureus. 2023;15(5).
38. Tralongo AC, Caspani F, Proserpio I, Volpi L, Campiotti L. Body mass index (BMI) influence on Cetuximab-induced antibody-dependent cellular cytotoxicity in advanced colon cancer. Internal and emergency medicine. 2023;18(1):297-303.

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