“POST-STROKE MOOD DISORDERS -A HOSPITAL BASED CROSS-SECTIONAL OBSERVATIONAL STUDY ON SOCIODEMOGRAPHIC, DIAGNOSTIC AND ANATOMICAL PATTERNS"

Main Article Content

Amrendra Kumar Singh
Naresh Solanki
Rahul Mishra
Umesh Pathak

Keywords

Clinical profile, Depression, Mood disorder, Sociodemographic

Abstract

Background: A number of patients developed psychiatric problems of diverse nature after stroke. Most of studies have focused on post-stroke depression and thus the hospital prevalence for individual mood disorders have not been explored yet. The goal of current study is to investigate hospital prevalence, sociodemographic patterns and anatomical distribution of mood disorders following stroke.


Method: The study was conducted on ninety patients developing mood disorders after stroke. Detailed socio-demographic characteristics, clinical profile along with psychiatric assessment were recorded in proforma specially designed for the study and analyzed using SSPS v26.


Results: Most of subjects (31,51.6%) were in the age range of 61-80 years. There was male preponderance (21,35%). Most patients were residing at rural areas (54, 90%) and were belonging to lower middle socio-economic status (28, 46%). Majority of subjects were unemployed (29,48.3%). Maximum subjects developed post-stroke depression (40, 66.6%) followed by mixed anxiety and depression (14, 23.3%). Rest of patients suffered from dysthymia (5,8.3%) and manic disorder (1,1.6%).


Conclusions: The post-stroke mood disorders are, generally, unrecognized and untreated, which has adverse impact on process of stroke rehabilitation. Better awareness and comprehension of the post-stroke mood disorders may aid in the early detection and management of them. A detailed psychiatric evaluation is mandatory in all patients of stroke to rule out psychiatric illness

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References

1. Hatano S. Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ. 1976; 54: 541–553.Medline
2. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990–2020: global burden of disease study. Lancet. 1997; 349: 1498–1504
3. Aigner A et al. Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults. Stroke. 2017 Jul;48(7):1744-1751. doi: 10.1161/STROKEAHA.117.016599. Epub 2017 Jun 15
4. José M. Ferro et al Neuropsychiatric sequelae of stroke Article in Nature Reviews Neurology • April 2016 DOI: 10.1038/nrneurol.2016.46
5. Hackett, M. L. et al Neuropsychiatric outcomes of stroke. Lancet Neurol. 13, 525–534 (2014).
6. Linden DE, Fallgatter AJ. Neuroimaging in psychiatry: from bench to bedside. Front Hum Neurosci. 2009;3:49. Published 2009 Dec 23. doi:10.3389/neuro.09.049.2009
7. Sukaina Rizvi et al Post Stroke Psychiatric Syndromes Published: August 17, 2018 Volume 9 Issue - 5 August 2018 DOI: 10.19080/PBSIJ.2018.09.555771.
8. Folstein MF et al “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–98.
9. 13. Robert G. Robinson, MD et al Poststroke Depression: A Review Can J Psychiatry. 2010 Jun; 55(6): 341–349
10. Robinson, R. G. & Jorge, R. E. Post-stroke depression: a review. Am. J. Psychiatry 173, 221–231 (2016). Mar 1;173(3):221-31. doi: 10.1176/appi.ajp.2015.15030363.
11. Nagaraja D et al. Feasibility study of stroke surveillance: Data from Bangalore, India. Indian J Med Res. 2009;130:396-403.
12. K.PARK, Park’s Textbook of PREVENTIVE AND SOCIAL MEDICINE, 25th edition, page no (744). Jabalpur, published by M/s BANARSIDAS BHANOT (Jabalpur), 482001(M.P.)
13. Vincent-Onabajo GO, Muhammad MM, Ali MU, Masta MA. Influence of Sociodemographic and Stroke-related Factors on Availability of Social Support among Nigerian Stroke Survivors. Ann Med Health Sci Res. 2015 Sep-Oct;5(5):353-7. doi: 10.4103/2141-9248.165258. PMID: 26500793; PMCID: PMC4594349.
14. Ayerbe L, et al. Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis. Br J Psychiatry. 2013;202(1):14–21.
15. Pooja Rajashekaran, et al, Post-stroke depression and lesion location: A hospital based crosssectional Study Indian J Psychiatry. 2013 Oct-Dec; 55(4): 343–348.
16. Sergio E. Starkstein MD (1990): relationship between anxiety disorders and depressive disorders in patients with cerebrovascular injury. Arch. Gen. Psychiatry: 47: 246-251.
17. Kim JS. Post-stroke Mood and Emotional Disturbances: Pharmacological Therapy Based on Mechanisms. J Stroke. 2016; 18(3):244–255.
18. Burvill P, Johnson G, Jamrozik K, Anderson C, Stewart-Wynne E. Risk factors for post-stroke depression. Int J Geriatr Psychiatry. 1997 Feb;12(2):219-26. doi: 10.1002/(sici)1099-1166(199702)12:2<219::aid-gps581>3.0.co;2-e. PMID: 9097215.
19. Mitchell AJ, Sheth B, Gill J, Yadegarfar M, Stubbs B, Yadegarfar M, Meader N. Prevalence and predictors of post-stroke mood disorders: A meta-analysis and meta-regression of depression, anxiety and adjustment disorder. Gen Hosp Psychiatry. 2017 Jul;47:48-60. doi: 10.1016/j.genhosppsych.2017.04.001. Epub 2017 Apr 3. PMID: 28807138.
20. Suk Yun Kang, Jong Won Paik, Restlessness with Manic Episodes due to Right Parietal Infarction Mov Disord. 2010 May; 3(1): 22–24.