SOLITARY RECTAL ULCER DISEASE IN PATIENTS PRESENTING WITH LOWER GASTROINTESTINAL BLEEDING: A STUDY AT THE GASTROENTEROLOGY WARD, HAYATABAD MEDICAL COMPLEX, PESHAWAR

Main Article Content

Dr. Salman Afridi
Dr. Muhammad Younas
Dr. Syed Hira Hassan
Dr. Fida Muhammad Khan
Dr. Shafqat Ali
Dr. Asif Khan
Dr. Aafaq Ahmad
Dr. Nowshad Khan

Keywords

Solitary rectal ulcer disease, lower gastrointestinal bleeding, diagnostic modalities, management outcomes

Abstract

Background: Solitary rectal ulcer disease (SRUD) is a condition that causes solitary ulcers or nodules in the rectum. It mostly affects adults, with a slight male a majority. SRUD is caused by a combination of factors, including recurrent straining during defecation, rectal prolapse, and anomalies in pelvic floor dynamics.


Aim: The aim of this research is to look at the clinical presentation, diagnostic methods, and therapeutic results of patients with SRUD who present with LGIB.


Study design: Descriptive Retrospective study.


Duration and Place of the study: This study was conduction at Gastroenterology Ward, Hayatabad Medical Complex, Peshawar between 10th September 2022 to 10th October 2023


Material and Methods: The 110 patients in this research varied in age from 18 to 93 years old and were admitted to the Gastroenterology Ward between September 10th, 2022 and October 10th, 2023 with a main complaint of LGIB. Patients with SRUD were included in the research after their medical records were evaluated. Demographic data, clinical characteristics, endoscopic results, histological data, and treatment outcomes were all examined.


Results: The 110 patients in this study ranged in age from 18 to 90, with 31.8% between 31 and 45. Second largest was 46–60 (27.3%), followed by 18–30 (22.7%). Only 13.6% of patients were 61–75, and 4.5% were 76 or older. The study included 54.5% male and 45.5% female subjects. In 63.6% of 110 instances, hematochezia was the main symptom. 22.7% of patients had stomach pain thereafter. Less prevalent were constipation (9.1%) and tenesmus (2.7%).


Conclusion: This research offers significant contributions by examining the demographic attributes, first manifestations, coexisting medical conditions, endoscopic observations, histological characteristics, and therapeutic results pertaining to patients diagnosed with SRUD. The results of this study align with other research studies, underscoring the need of promptly identifying and effectively addressing this disease.

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References

1. Price AB, Morson BC. Inflammatory bowel disease: the surgical pathology of Crohn's disease and ulcerative colitis. Human pathology. 1975 Jan 1;6(1):7-29.
2. Hreinsson JP, Gumundsson S, Kalaitzakis E, Björnsson ES. Lower gastrointestinal bleeding: incidence, etiology, and outcomes in a population-based setting. European journal of gastroenterology & hepatology. 2013 Jan 1;25(1):37-43.
3. D’Hoore A. Total Rectal Prolapse, Internal Prolapse–Solitary Rectal Ulcer Syndrome and Rectocele. InAnorectal and Colonic Diseases: A Practical Guide to Their Management 2009 Jan 1 (pp. 627-649). Berlin, Heidelberg: Springer Berlin Heidelberg.
4. Cappell MS, Friedel D. The role of sigmoidoscopy and colonoscopy in the diagnosis and management of lower gastrointestinal disorders: endoscopic findings, therapy, and complications. Medical Clinics. 2002 Nov 1;86(6):1253-88.
5. CHOI JM, KIM JH. Management of Urinary and Bowel Dysfunction in Multiple Sclerosis. Primer on Multiple Sclerosis. 2016 Jan 29:233.
6. Barnert J, Messmann H. Diagnosis and management of lower gastrointestinal bleeding. Nature Reviews Gastroenterology & Hepatology. 2009 Nov;6(11):637-46.
7. Oakland K, Chadwick G, East JE, Guy R, Humphries A, Jairath V, McPherson S, Metzner M, Morris AJ, Murphy MF, Tham T. Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology. Gut. 2019 May 1;68(5):776-89.
8. Whitehurst BD. Lower gastrointestinal bleeding. Surgical Clinics. 2018 Oct 1;98(5):1059-72.
9. Cunningham C. Lower gastrointestinal surgery. Fundamentals of Surgical Practice. 2011 Mar 17:430.
10. Khairat S, Marc D, Crosby W, Al Sanousi A. Reasons for physicians not adopting clinical decision support systems: critical analysis. JMIR medical informatics. 2018 Apr 18;6(2):e8912.
11. McGahan M, Kucharski G, Coyer F, Paper WA. Nurse staffing levels and the incidence of mortality and morbidity in the adult intensive care unit: a literature review. Australian Critical Care. 2012 May 1;25(2):64-77.
12. Sun C, Hull T, Ozuner G. Risk factors and clinical characteristics of rectal prolapse in young patients. J Visc Surg. 2014 Dec;151(6):425-9.
13. Jadelis K, Miller ME, Ettinger Jr WH, Messier SP. Strength, balance, and the modifying effects of obesity and knee pain: results from the Observational Arthritis Study in Seniors (OASIS). Journal of the American Geriatrics Society. 2001 Jul;49(7):884-91.
14. Harbord M, Eliakim R, Bettenworth D, Karmiris K, Katsanos K, Kopylov U, Kucharzik T, Molnár T, Raine T, Sebastian S, de Sousa HT. Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 2: current management. Journal of Crohn's and Colitis. 2017 Jul 1;11(7):769-84.
15. Park SH, Song CW, Kim YB, Kim YS, Chun HR, Lee JH, Seol WJ, Yoon HS, Lee MK, Lee JH, Bhang CS. Clinicopathological characteristics of colon cancer diagnosed at primary health care institutions. Intestinal research. 2014 Apr 29;12(2):131-8.
16. Bulloch G, Seth I, Alphonse S, Sathe A, Jennings M, Sultan D, Rahmeh R, McNab AA. Prevalence of obstructive sleep apnea with floppy eyelid syndrome: a systematic review and meta-analysis. Ophthalmic Plastic and Reconstructive Surgery. 2023 Mar 16;39(3):243-53.
17. Cox J, Isip R, Reid M, Hulme D, Marra A. Predictors of Hospital Readmission in Patients Undergoing Creation of an Intestinal Ostomy. Journal of Wound, Ostomy and Continence Nursing. 2023 May 1;50(3):215-21.
18. Rentmeester LL, Burton DW, Fitzgerald RL, Clark RF. 2014 ACMT annual scientific meeting—march 28–30, 2014 Phoenix, AZ, USA. J. Med. Toxicol. 2014;10:65-99.
19. Vanella G, Capurso G, Burti C, Fanti L, Ricciardiello L, Lino AS, Boskoski I, Bronswijk M, Tyberg A, Nair GK, Angeletti S. Gastrointestinal mucosal damage in patients with COVID-19 undergoing endoscopy: an international multicentre study. BMJ open gastroenterology. 2021 Feb 1;8(1):e000578.
20. Abid S, Khawaja A, Bhimani SA, Ahmad Z, Hamid S, Jafri W. The clinical, endoscopic and histological spectrum of the solitary rectal ulcer syndrome: a single-center experience of 116 cases. BMC Gastroenterol. 2012 Jun 14;12:72.
21. Pollock A, Baer G, Campbell P, Choo PL, Forster A, Morris J, Pomeroy VM, Langhorne P. Physical rehabilitation approaches for the recovery of function and mobility following stroke. Cochrane Database Syst Rev. 2014 Apr 22;2014(4):CD001920.
22. Sangrasi AK, Leghari AA, Memon A, Talpur AK, Qureshi GA, Memon JM. Surgical site infection rate and associated risk factors in elective general surgery at a public sector medical university in Pakistan. Int Wound J. 2008 Mar;5(1):74-8.

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