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Mahalingam Jeyakumar
Kulanthaivel Langeswaran
Saranya Arumugam
Bharatha Rathna Pillappan
Durai Deepika


Silver nanoparticles, Antifungal, Cassia alata, Human Fibroblast cell line


The primary objective of the present study is to synthesis and characterization silver nanoparticles using Cassia alata aqueous flower extract and investigate the antifungal activity and cytotoxicity study. Cassia alata aqueous flower extract have been effectively used for the synthesis of silver nanoparticles and demonstrated the efficacy of Cassia alata flower as natural renewable and low costing bioreduction agent of silver. The characterizations of AgNPs such as UV-visible, FTIR, SEM, EDX and XRD. We have synthesized AgNPs of 20 nm in size with spherical shape using aqueous extract of Cassia alata. AgNPs synthesized by flower extract were very distinct with very small size, crystalline nature and clearly proved their biomedical importance by exhibiting strong antifungal activity against skin pathogens. In addition cell line study reveals that low concentration of AgNPs was showed a 98% cell viability. Thus AgNPs possess important applications in biomedical or pharmaceutical industry for the preparation of antifungal skin ointments.

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