PATTERN OF ANTIBIOTIC RESISTANCE IN STROKE PATIENTS WITH UTI AND ITS DETERMINANTS

Main Article Content

Salma Zeb
Sumaira Bakhtiar
Zafar Mehmood
Laila Zeb
Muhammad Bilal Awan
Zia Ullah Chamkani

Keywords

Stroke, Urinary Tract Infection, Antibiotic Resistance, Microorganisms

Abstract

Background: Stroke is the world's second leading cause of mortality and morbidity. Stroke survivors usually have UTIs along with other infections as they weaken the immune system. UTIs are common after a stroke and usually result in death or disability.


Objective: The main objective of this study is to discover and characterise the pattern of antibiotic resistance in UTIs among 80 stroke patients.


Study Design:  Descriptive cross-sectional study


Place and Duration: This Study was conducted at the Department of Medicine, Lady Reading Hospital, and Peshawar between September 2022 and February 2023


Material and Methods: The study included 80 patients over the Age of 18 of both genders. Urine cultures were collected before antibiotics were administered to UTI-symptomatic stroke patients. Relevant data was entered in a pre-designed proforma to adjust for confounders and bias.


Results: The study had 80 patients, 45 (56.25%) male and 35 (43.75%) female. Patients had a mean age of 62.4±10.3 years. 70% of patients had ischemic strokes, while 30% had hemorrhagic strokes. The average NIHSS score was 9.7±3.6. Many patients (35%) had recurrent strokes and 95% needed bladder catheterisation. Most patients (72.5%) had diabetes. E. coli caused 45 (56.25%) UTIs. (90%)  were sensitive to Carbapenems, nitrofurantoin, and fosfomycin only.


Conclusion: This study, focusing on urinary tract infections (UTIs) in stroke patients, has disclosed essential elements of patient demographics, clinical profiles, causative microorganisms, and treatment resistance trends.

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